Dr. Edward F. Group III, DC, ND, DACBN
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| In this chapter, my goal is to teach you how to heal yourself by activating your own internal self-healing mechanism. The body is the best healing instrument in the world. Our bodies are designed to eliminate any disease!
Disease or poor health typically occurs when your body becomes so contaminated with toxic residue that your internal self-healing mechanism becomes suppressed. To reactivate your self-healing mechanism, you must begin cleansing and purifying your body from years of toxin buildup. |
Elaine Magee
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 In the control group, neither lycopene nor vitamin E alone significantly reduced cancer cells. What mechanism might enable lycopene and vitamin E to have synergy in reducing prostate cancer growth? Nobody knows the answer yet, but "most likely the mixture acts by optimizing the mechanisms of both compounds alone," explains Wytske van Weerden, PhD, the lead researcher of the study at Erasmus University in Rotterdam, the Netherlands.
Vitamins C and E work with beta-carotene to lower LDL cholesterol. |
Melody Petersen
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 He added that the problem was "mechanism based as we worried it was." Scientists often refer to a drug's mechanism when they explain how it works. They now knew there was something about how Vioxx worked in the body that was harming some patients' hearts.
Merck's message to doctors and the American public was a different one, however. In press releases the company explained away the heart attacks suffered by the patients taking Vioxx in the study. Executives said that Merck had done other studies that had not found an increased risk of heart problems in patients taking Vioxx. |
Dr. Edward F. Group III, DC, ND, DACBN
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| Disease or poor health typically occurs when your body becomes so contaminated with toxic residue that your internal self-healing mechanism becomes suppressed. To reactivate your self-healing mechanism, you must begin cleansing and purifying your body from years of toxin buildup. You also must follow my recommendations in this book and eliminate the root cause of these toxins from your daily life.
I recommend the following the 4-Step Body Cleanse process to free your entire body of built-up toxic residue.
Dr. |
Joerg Gruenwald, Ph.D.
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 Drug Interactions: Although reports are sketchy, and most involve animal subjects and in vitro research, there is a strong possibility that Feverfew may interact with antithrombotic medications such as aspirin and warfarin. The mechanism of action is believed to be inhibition of arachidonic acid, which is a precursor for prostaglandins that are involved in the clotting mechanism.
DOSAGE
Mode of Administration: Feverfew preparations are used both internally and externally.
Preparation: To make an infusion, use 2 teaspoonfuls of the drug per cup, allow to draw for 15 minutes. |
Mark Lynas
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 This mechanism is confirmed by computer models of current and likely future climate. A team led by Martin Hoerling of the US National Oceanic and Atmospheric Administration found that Africa was literally split in half by global warming.1 The northern half is likely to see a recovery in rainfall, whilst the southern half gets progressively drier. Hoerling's team did not use just one computer model to get this result: they saw the same mechanism repeatedly take place in sixty different simulations using five different models, making their prediction very robust in scientific terms. |
Joerg Gruenwald, Ph.D.
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| The mechanism of action is believed to be inhibition of arachidonic acid, which is a precursor for prostaglandins that are involved in the clotting mechanism.
DOSAGE
Mode of Administration: Feverfew preparations are used both internally and externally.
Preparation: To make an infusion, use 2 teaspoonfuls of the drug per cup, allow to draw for 15 minutes. To make a strong infusion, double the amount and allow to draw for 25 minutes.
Dosage: The recommended daily dosage is 50 mg to 1.2 gm of leaf powder. In folk medicine, 3 cups of the infusion are taken per day. |
Mark Lynas
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| So could such a mechanism plausibly repeat in the twodegrees-warmer world? Most studies conclude that the height of the Eemian interglacial saw temperatures between 1 and 2°C higher than today's, suggesting that it may be a useful analogue for a warmer climate in the future. And if it did take China's monsoon climate longer to make the transition from cool/dry to warm/wet 129,000 years ago, as some scientists believe, this does suggest a possible causal mechanism behind the droughts and rising temperatures that have struck northern China in recent years. |
Michael T. Murray and Michael R. Lyon
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 The basic underlying mechanism in the chronically obese mice and Pima Indians with the thrifty gene is a natural craving for carbohydrates that causes consumption of them whenever they are available, even if hunger is not present. They also possessed the ability to make more insulin and store the excess calories consumed as fat. Pima Indians with the thrifty genotype also easily develop resistance to insulin when they consume excess carbohydrates. What this additional mechanism produces is an even greater ability to store fat and as a result enables them to live through famines. |
Bill Sardi
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 While gamma tocopherol is a very similar molecule to alpha tocopherol, it appears to inhibit cancer cell growth by a mechanism apart from its antioxidant properties. [FASEB Journal 16: 1952-54, 2002]
Then there is the other family of vitamin E, the tocotrienols, primarily derived from palm and rice bran oil in dietary supplements. The body naturally concentrates these compounds in adipose tissue, the main type of tissue that constitutes the breast. |
| Drug versus natural therapy: same mechanism ... 96 Reasons why chemotherapy doesn't work ... 97
Most tumors are not sensitive to the drugs... 98
Drug resistance ... 98
Overcoming cancer resistance ... 98
Glutathione ... 99
Natural inhibition of drug resistance ... 100 Garlic and chemotherapy drug resistance ... 100 Electric pulses ... 100
CO
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Treatmen
P78- 1C
The future of chemotherapy ... 101 Gene targeted drugs ... 101 The outrageous cost of gene-targeted drugs Selective chemotherapy... 104
When treatment is over, now what? ... 104
A man fights for the life of his wife ... |
| Actually, a defective mechanism in the mitochondria is the problem. [Mol Cancer 1:9, 2002] Acidity surrounding the tumor cell is caused by metabolism within the cell, and not by lack of oxygen. [Neoplasia 5:135-45, 2003]
Mitochondria produce up to 80% of the energy needs of a cell. Mitochondrial dysfunction is related to a diverse number of adult-onset diseases including cancer, diabetes, deafness, stroke and other maladies.
The DNA in mitochondria is more vulnerable to mutations than the DNA in the nucleus of the cell. |
Thomson Healthcare, Inc.
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| Anti-Inflammatory Effects: Cat's Claw appears to inhibit Tumor Necrosis Factor alpha, as well as function as an antioxidant, which may explain its mechanism of action in treating inflammatory disorders such as osteoarthritis, arthritis, and gastritis in traditional settings in South America (Hardin, 2007). In addition, the sterol components of Cat's Claw (beta-sitosterol, stigmasterol, and campesterol) have been found to have anti-inflammatory activity (Senatore et al, 1989). |
Bill Sardi
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| Their mechanism - to alter the human immune system to selectively attack tumor cells - may disrupt normal immune surveillance against infection and may induce undesirable autoimmune reactions. Furthermore, vaccines are only expected to be efficient against small tumors and they may not shrink tumor size. Cancer vaccines may be more useful in the early stages of cancer. [Toxicology 214: 151-61, 2005]
Cancer vaccines are a fertile area for research, but currently are not a practical answer for most types of solid tumors. |
Thomson Healthcare, Inc.
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| In a separate study, an infusion of Stevia was tested in a cell cycle test model (Allium cepa meristems) to determine if the mechanism of action involved c-mitotic effects. No adverse effect on the cell cycle was observed with the administration of Stevia suggesting that the contraceptive effects may not be due to changes in the chromosome cycle (Schvartzman et al, 1977). clinical trials
Diabetes
Investigators studied the acute effects of stevioside in 12 patients with type 2 diabetes, hypothesizing that supplementation with stevioside could cause a reduction in postprandial blood glucose. |
Shannon Brownlee
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 His patient—we'll call her Jean Crofton—is lying on a slim, ten-foot-long bed called a catheterization table, which is mounted on a mechanism that allows the doctor to move the patient back and forth under an X-ray machine. Crofton is awake but groggy from a sedative. She lies quietly as two nurses shave and scrub both sides of her groin before draping her entire body first in sterile blue paper and then a large plastic sheet. A Moody Blues melody fills the room from Altschuler's iPod speakers as he and a technician don gloves and paper gowns. |
Bill Sardi
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| Another mechanism by which butyrate thwarts colon cancer is its gene-signaling capabilities. Butyrate works like a gene-targeted drug, similar to the way widely heralded drugs like Erbitux and Herceptin work. Butyrate causes a coil-like structure called histories to tightly wrap around genes, switching genes that control cancer growth "off." Butyrate is gene therapy. [Oncological Research 14: 427-38, 2004]
—? Butyrate also works as a natural COX-2 inhibitor, working in a similar fashion to COX-2 inhibiting drugs, but without the cardiovascular side effects. |
Joerg Gruenwald, Ph.D.
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| Inhibition of 5- and 12-lipoxygenase by a non-redox mechanism. In: PM 62(5):397-401. 1996.
Willaman JJ and Hm-Li L (1970) Lloydia 33 (3A):1.
Further information in:
Chan, EH et al, (Eds), Advances in Chinese Medicinal Materials Research, World Scientific Pub. Co. Singapore 1985.
Frohne D, Pfander HJ, Giftpflanzen - Ein Handbuch fur Apotheker, Toxikologen und Biologen, 4. Aufl., Wiss. Verlagsges. mbH Stuttgart 1997.
Hansel R, Keller K, Rimpler H, Schneider G (Hrsg.), Hagers Handbuch der Pharmazeutischen Praxis, 5. Aufl. |
Thomson Healthcare, Inc.
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| Study of the mechanism whereby anthocyanosides potentiate the effect of catecholamines on coronary vessels. Fitoterapia; LVI (2):67-72. 1985a
Bettini V, Guerra B, Martino R et al. Contractile responses of isolated rat stomach to stimulation of post-ganglionic cholinergic fibers in the presence of Vaccinium myrtillus anthocyanosides. Fitoterapia; LVII (4):211-216. 1986
Bettini V, Mayellaro F, Pilla I et al. Mechanical responses of isolated coronary arteries to barium in the presence of Vaccinium myrtillus anthocyanosides. Fitoterapia; LVI (1):3-10. 1985
Bettini V, Mayellaro F, Ton P et al. |
Joerg Gruenwald, Ph.D.
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| Wittstock U, Lichtnow KH, Teuscher E, Effects of cicutoxin and related polyacetylenes from cicuta virosa on neuronal action potentials: a comparative study on the mechanism of the convulsive action. In: PM 63(2): 120-124. 1997.
Wittstock U, Lichtnow KH, Teuscher E, Effects of polyacetylenes from Cicuta virosa on the electrical activity of molluscan giant neurones. In: PM 61 (Abstracts of 43rd Ann Congr):84. 1995.
Wittstock U, Wurz G, Hadacek F, Greger H, Teuscher E, Biocative polyacetylens from Cicuta virosa. In: PM 58(7):A722. 1992. |
Bill Sardi
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| This is a survival mechanism.
So anemia, paleness and fatigue are commonly experienced by cancer patients. One study shows that 26% of cancer patients being treated with chemotherapy were anemic. [Value Health 8: 149-56, 2005] Another study indicates up to 63% of patients undergoing chemotherapy were anemic. [Oncology 68: 3-11, 2005]
The modern remedy to this problem has been to use a hormone-like drug to stimulate red blood cell production. Drugs such as Procrit, Epogen and Aranesp are frequently used. |
Paul D. Blanc, M.D.
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 Some plants have come up with an entirely different way of taking poorly soluble polymers and "packaging" them for export. This mechanism also has crirical implications for glue making, because it provides an important clue for a possible way to engineer an alternative to toxic chemical solvents. By suspending otherwise insoluble polymers as microscopic droplets, certain specialized plants can turn them into water-based solutions. Like resins, these water-suspended polymers also reach the plant's surface when needed, particularly after injury. |
Dr. Steve Blake
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 The most likely mechanism for this urinary loss is the competition between calcium and sodium for reabsorption in the tubules of the kidney.
If this extra 86 mg of calcium is absorbed from food sources in the intestines, then about 287 mg of extra dietary calcium is needed to account for this loss. Why is so much dietary calcium needed to replace smaller losses of urinary calcium? This is because calcium absorption from the intestines is not very efficient. |
Paul D. Blanc, M.D.
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| Nitroethane does not act as a poison through the same mechanism as acetonitrile. Acetonitrile breaks down to cyanide and blocks the body's ability to use oxygen, thus stopping critical life functions. Nitroethane, acting more rapidly, simply blocks the blood's ability to ttans-port oxygen in the first place. For example, in the case of a nitroethane-poisoned twenty-month-old who arrived at the hospital emergency room blue and short of breath, almost half of the blood's capacity to carry oxygen had been blocked. Fortunately, a chemical antidote was available and the infant survived. |
| All of the mustard toxins were found to share a common mechanism: they attack DNA, binding to this critical molecule and thus interfering with its function. Although this accounts for nitrogen mustard's potency in killing dividing cells, such as the cells of a tumor, it also gives nitrogen mustard the ability to cause genetic mutations. Thus the potential benefits of nitrogen mustard were also found to be linked to a new risk: second cancers appearing in long-term cancer survivors. |
| Cause and effect are nearly impossible to establish when a disease is common, potentially attributable to multiple factors, and no different in form whether caused by a suspect toxin or occurring through another mechanism. This is the case with stroke, for example, as well as heart attack and Parkinson's disease, all of which are common health problems that have been linked to carbon disulfide.
Moreover, despite carbon disulfide's many years of study, possible new dangers from it continue to emerge. |
| A key first step in dissecting any toxic mechanism requires teasing out its dose response. In the simplest relationship, increasing exposure with each test predictably induces a greater response. This srraight-line step-up, however, is far from universal.
Some substances manifesr a complex dose response. For example, once allergic sensitization occurs, minute exposure to an otherwise nontoxic material can induce a life-threatening response: anaphylaxis. |
| Although physicians were in favor of the new red phosphorous, the innovation proved less popular with consumers, because the striking mechanism was more complicated, requiring a special box for ignition. It was even less popular with manufacturers of the strike-anywhere matches; the red phosphorous was more expensive than the yellow, cutting into the profit margin of those who went so far as to substitute the red for the yellow.
In 1874 Denmark wisely banned the production and sale of yellow phosphorous matches, requiring use of the safer substitute. |
Jeffrey M. Smith
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 They attack fundamental processes, such as the cycle by which a cell divides and the mechanism for creating proteins from RNA.111 If these were damaged in human beings, it could have serious consequences and may cause disease. (Disrupting the cell cycle, for example, can lead to cancer.)
Since these metabolic activities are similar in plants and humans, a toxic viral protein that disables them in crops might attack that same process in people. Viral proteins from one kingdom have in fact been shown to be toxic to organisms from other kingdoms. |
| While the mechanism of how GM soy suppressed enzyme production is unclear, such a dramatic drop may certainly create problems with carbohydrate digestion.
One-month-old GM-fed mice also produced less zymogens, but the differences became negligible in subsequent ages. Zymogens are digestive enzymes in a pre-active state, which become active when released into the intestine by the pancreas. Until that time, they are held in the pancreas in zymogen granules. The size of these granules was consistently smaller in GM-fed mice, with the highest difference of 39% in month five. |
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