Dr. Abram Hoffer, MD, FRCP (C) and Dr. Harold D. Foster, PhD
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 The vitamin B-3 had no direct effect on tumor volume in these animals; however, it decreased 86% after irradiation in niacinamide-treated mice, and remained 79% lower at 4 weeks. Mitotic activity also remained low in niacinamide-treated animals after irradiation, but returned to pre-irradiation levels in non-treated mice. Kjellen suggested, therefore, that niacinamide might have a role in the treatment of malignant tumors.
Other authors also have suggested that niacinamide increases the toxicity of irradiation against tumors in mice. M.R. Horsman and colleagues1?-^ and D.J. |
by Michael Murray, N.D. and Joseph Pizzorno, N.D.
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| On the other end of the spectrum, opponents are quick to point out the concern that irradiation produces altered food molecules, destroys most of the vitamins, and alters the fatty acid structures in food.
Even though there is a worldwide standard for food irradiation safety that was accepted in 1963 by the Codex Alimentarius Commission, a joint body of the U.N. Food and Agriculture Organization and the World Health Organization, our feeling is that the science conducted so far on food irradiation is far from complete. |
Gabriel Cousens, M.D.
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 In addition, food irradiation plants are unsafe. Radioactive accidents have already happened at the few food-irradiation plants that exist in this country and worldwide.
In attempting to determine what to do about food irradiation, the FDA reviewed 441 toxicity studies. The chairperson in charge of new food additives at the FDA, Dr. Marcia van Gemert, testified that all 441 of the studies were flawed. The FDA, however, determined that at least five studies were acceptable under 1980 toxicological standards. |
Bill Sardi
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 Journal Nutrition 134:3182-3S, 2004]
However, laboratory experiments also show that growth-inhibiting doses of vitamin E (alpha tocopherol succinate), vitamin C and vitamin A administered before and after irradiation enhance the effect of x-ray radiation on cancer cells and protect normal cells against some radiation damage. Vitamin A and beta-carotene at high doses, administered daily before x-ray-irradiation produces more than a 90% cure rate in mice with implanted breast cancer cells, whereas treatment with radiation alone or antioxidants alone are ineffective. |
Abram Hoffer, PhD, MD, FRCP(C) and Dr. Jonathan Prousjy, DPHE, DSC, ND, FRSH
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 Selenium given to hairless pigmented mice protected them against damage from ultraviolet irradiation. Both a lotion containing 0.02% L-selenomethionine and oral administration of water containing 1.2 p.p.m. were protective. These dosages did not cause any toxic reactions. This study concluded that "SeMet is effective in protecting against skin cancer induced by UV irradiation, both by retarding the onset and reducing the number of lesions." They were also "effective in reducing the acute damage induced by UV irradiation-inflammation (sunburn), blistering, and pigmentation (tanning). |
KC Craichy
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 In 1992, the FDA approved irradiation of poultry; and in 1997, it approved irradiation of red meats. There are many foods now that are being delivered to our supermarkets that have gone through this process. The food irradiation industry and the FDA claim that the food itself is not radioactive or contaminated. However, somewhat contradictorily, the FDA has also reported that irradiated food can increase the risks for developing tumors in laboratory animals; this report was made public in 1968. |
Mary-Ann Shearer
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 An additive not generally regarded as such is irradiation or radurization. irradiation is a preservation treatment that uses very large doses of ionizing radiation, which produces a change in food in order to ensure a longer shelf life. The materials used to irradiate food are cobalt 60 or cesium 137, common nuclear waste products. irradiation is not new and has been around without our knowledge since 1916 when the first fruit experiments were conducted on strawberries. |
Gabriel Cousens, M.D.
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| Some of these radiolytic products are unique to the irradiation process and have not been adequately identified or tested for toxicity.
Irradiating food destroys somewhere between 20 and 80 percent of the vitamins, including A, B2, B3, B6, B12, folic acid, C, E, and K. Amino acids and essential fatty acids are also destroyed. Enzymes, of course, are destroyed, as are the bio-photons.
In addition, food irradiation plants are unsafe. Radioactive accidents have already happened at the few food-irradiation plants that exist in this country and worldwide. |
KC Craichy
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| In 1992, the FDA approved irradiation of poultry; and in 1997, it approved irradiation of red meats. There are many foods now that are being delivered to our supermarkets that have gone through this process. The food irradiation industry and the FDA claim that the food itself is not radioactive or contaminated. However, somewhat contradictorily, the FDA has also reported that irradiated food can increase the risks for developing tumors in laboratory animals; this report was made public in 1968. |
by Michael Murray, N.D. and Joseph Pizzorno, N.D.
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| In addition to reducing the risk for foodborne illness, food irradiation considerably reduces losses due to spoilage. On the other end of the spectrum, opponents are quick to point out the concern that irradiation produces altered food molecules, destroys most of the vitamins, and alters the fatty acid structures in food.
Even though there is a worldwide standard for food irradiation safety that was accepted in 1963 by the Codex Alimentarius Commission, a joint body of the U.N. |
| On one end of the spectrum, proponents say that food irradiation is safe and, in fact, necessary to make the food supply safer. In addition to reducing the risk for foodborne illness, food irradiation considerably reduces losses due to spoilage. On the other end of the spectrum, opponents are quick to point out the concern that irradiation produces altered food molecules, destroys most of the vitamins, and alters the fatty acid structures in food. |
Phyllis A. Balch, CNC
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 Irradiated food must be labeled with the international symbol for irradiation.
While organizations like the World Health Organization and the American Medical Association endorse irradiation, there are consumer activists who feel emphasis should be placed on raising healthier livestock and uncontaminated fruits and vegetables. Detractors also say that irradiation kills bacteria by blowing up their genes, which can create free-radical molecules that, in turn, contribute to disease and the aging process. |
Dr. Abram Hoffer, MD, FRCP (C) and Dr. Harold D. Foster, PhD
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| This suggestion also applies to people exposed to irradiation from any other source.
Niacin may play a role in reducing the number of birth defects. H. Gotoh and colleagues, for example, reported that nicotinamide significantly decreased urethane-induced malformations when given intraperitoneally to pregnant mice.2"* Beyond this, M.E. Scheulin and colleagues found that niacin also reduced the negative impacts of adriamycin, a widely used agent in chemotherapy, on the heart.25 As a result, they suggested that niacin may offer some cardioprotection during long-term adriamycin chemotherapy. |
Thomson Healthcare, Inc.
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 A total of 194 women receiving breast or chest-wall irradiation were included in the study. Skin dermatitis was scored weekly during the trial by patients and by healthcare providers. Aloe vera gel did not protect against radiation therapy-induced dermatitis (Williams, 1996).
A double-blind, placebo-controlled study with 108 breast cancer patients that were treated with a minimum 50cGy radiation dose to the breast or chest wall were evaluated for dermatitis scores following the use of topical Aloe vera. |
Dr. Abram Hoffer, MD, FRCP (C) and Dr. Harold D. Foster, PhD
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| Other authors also have suggested that niacinamide increases the toxicity of irradiation against tumors in mice. M.R. Horsman and colleagues1?-^ and D.J. Chaplin and coworkers20 found that nicotinamide was the best drug for increasing sensitivity to radioactivity as compared to a series of analogues. This vitamin probably worked because it enhanced blood flow to the tumor.21
Nicotinamide also appears to enhance the effects of chemotherapy. |
| The effects of topical and oral L-selenomethionine on pigmentation and skin cancer induced by ultraviolet irradiation. Nutrition and Cancer, 1992;17:123-33.
SAFETY
Risks and Benefits
As with any form of therapy, vitamin B-3 needs to be evaluated on the basis of its risks and benefits. In a recent issue of the Journal of Orthomolecular Medicine, Dr Hoffer has reviewed the literature on the negative and positive side effects of vitamin B-3.1 |
Phyllis A. Balch, CNC
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| While organizations like the World Health Organization and the American Medical Association endorse irradiation, there are consumer activists who feel emphasis should be placed on raising healthier livestock and uncontaminated fruits and vegetables. Detractors also say that irradiation kills bacteria by blowing up their genes, which can create free-radical molecules that, in turn, contribute to disease and the aging process. They also say there is a possibility that irradiation will lead to new strains of radiation-resistant bacteria. |
Thomson Healthcare, Inc.
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| Ribaya-Mercado JD, Garmyn M, Gilchrest BA, et al: Skin lycopene is destroyed preferentially over beta-carotene during ultraviolet irradiation in humans. J Nutr 125(7): 1854-1859. 1995.
Riso P, Pinder A, Santangelo A, et al: Does Tomato consumption effectively increase the resistance of lymphocyte DNA oxidative damage? Am J Clin Nutr 69(4)712-718. 1999.
Sengupta A, Das S. The anti-carcinogenic role of lycopene, abundantly present in Tomato. Eur J Cancer Prevention 8(4):325-330. 1999.
Sharma SK, LeMaguer M. Lycopene in Tomatoes and Tomato pulp fractions. Ital J Food Sci 8(2): 107-113. 1996. |
| Gamma irradiation, on the other hand, controls Salmonella and E coli 0157:H7 on alfalfa sprouts at doses approved for irradiating meat (which are higher than the 1.0 kiloGray dose used for fruits and vegetables) without affecting germination of seeds and constitutes the best preventive measure now available for decontaminating sprouts and other agricultural products (Taormina et al, 1999; Stephenson, 1997). One case of human listeriosis has been linked to consumption of alfalfa tablets (Farber et al, 1990). |
| All patient received 5-fluorouracil and cisplatin plus mediastinal irradiation. Blood chemistries, lymphocyte counts, and gut barrier functions were completed before treatment and on days 7, 14, and 28. Glutamine prevented a reduction in lymphocyte count on day 7 (p<0.05) but there were no differences between groups on days 14 and 28. Blast formation of lymphocytes was maintained by glutamine on days 7 and 14 (p<0.05). Urinary excretion of phenolsulfonphthalein was greater in the control group on day 7 only (p<0.05). |
| Another in vitro study demonstrated a protective effect of Grape Seed proanthocyanidins against peroxidation of polyunsaturated fatty acids (PUFA) by UV-C irradiation (Bouh-amidi et al, 1998). Mice fed Grape Seed proanthocyanidin extract (GSPE) had a decrease in 12-O-tetradecanoylphorbol-13-acetate (TPA) induced production of reactive oxygen species, DNA fragmentation in hepatic and brain tissues and lipid peroxidation. |
| Phase III randomized trial of Calendula officinalis compared with Trolamine for the prevention of acute dermatitis during irradiation for breast cancer. J Clin Oncol; 22: 1447-1453. 2004.
Pyrek J. Roczniki Chemii 51:1141, 2331, 2493, 1977.
Samochowiec E et al. Wiad Parazytol 25(1):77, 1977. Samochowiec L. Pharmacological study of saponosides from Aralia mandshurica Rupr et Maxim and Calendula officinalis. In: Herba Pol; 29(2):151-155, 1983.
Vecherko LP et al. Khim Prir Soed 11(3):366, 1975.
Weiss RF. Herbal Medicine. Ab Arcanum, Gothernburg, Sweden, 1985.
Wilkomirski B. |
Abram Hoffer, PhD, MD, FRCP(C) and Dr. Jonathan Prousjy, DPHE, DSC, ND, FRSH
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| This study concluded that "SeMet is effective in protecting against skin cancer induced by UV irradiation, both by retarding the onset and reducing the number of lesions." They were also "effective in reducing the acute damage induced by UV irradiation-inflammation (sunburn), blistering, and pigmentation (tanning)." Selenium is a good antioxidant. It is synergistic with vitamin E, the body's best known fat-soluble antioxidant. The daily recommended dose is 200 meg. We have given 600 meg and more to certain patients for many years and have seen no toxic side effects. |
| We would, therefore, suggest that the three best known natural antioxidants - ascorbic acid, vitamin E, and selenium -be used to protect people against the toxic effect of excessive ultraviolet irradiation.
Selenium is also a preventive nutrient. Selenium given to hairless pigmented mice protected them against damage from ultraviolet irradiation. Both a lotion containing 0.02% L-selenomethionine and oral administration of water containing 1.2 p.p.m. were protective. These dosages did not cause any toxic reactions. |
Andreas Moritz
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 Choose to have healthier menus, using organic foods, and transition to organic ingredients (no pesticides, antibiotics, hormones, irradiation or genetically engineered ingredients). Read the food labels and look out especially for the following chemicals:
• Sunset yellow (El 10 or FD&C Yellow 6) is a dye used in, among other foods, orange jellies and squashes, apricot jam and packet soups. It's also in Smarties, and at least one variety of Lucozade (a popular British and now also American sports drink). |
Dr. Steve Blake
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 However, ultraviolet light and other forms of irradiation including visible light destroy riboflavin, as shown in Figure 1-8.
Riboflavin is destroyed by light and ultraviolet light
( uv )
\\\
Visible
Ultraviolet light light
Figure 1-8 Riboflavin is destroyed by light and UV light.
Vitamin B3—Niacin, Feel the Burn
The disease pellagra has been known since the introduction of corn to Europe in the 1700s. The connection between pellagra and niacin was confirmed in 1937 by an American scientist who was searching for the cause of pellagra. |
Phyllis A. Balch, CNC
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| They also say there is a possibility that irradiation will lead to new strains of radiation-resistant bacteria.
Price is another issue—irradiation increases the cost of food production, which is always passed on to the consumer. In the opinion of Jack Challem, a nutrition reporter and author, "Irradiation is just another way of tampering with a food supply that has already been tampered with far too much. |
Kevin Trudeau
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 Formaldehyde, cancer-causing benzene, and mold toxins form because of irradiation. irradiation is being done to most of our food supply. This is why you must be eating 100 percent organic food. The multinational corporations are not interested in your health, but are only interested in their profits, and from my inside information I personally know that the food industry is purposely making us sick so that it can profit from the sale of drugs.
To buy this book go to www.naturalcures.com, or you can simply call 1-800-787-8780, or go to www.drrapp.com. |
Connie Bennett, C.H.H.C. with Stephen T. Sinatra, M.D.
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 On the other hand, regular crops are contaminated with pesticides, other chemicals, and irradiation, and undergo genetic modification. Organic foods are exposed to fewer nitrates and other harmful residues. sf Organic foods are healthier for children in their growth years. Some foods that kids favor, such as peanut butter, raisins, and peaches, have among the highest levels of pesticide residue, and these pesticides can cause neurological damage in children.
¦ Organic foods taste better, thanks to the better-balanced soils in which they're grown. |
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