Hydroxytyrosol

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You Don't Have to be Afraid of Cancer Anymore Bill Sardi See book keywords and concepts

A special extra concentrated olive extract yields a potent antioxidant called hydroxytyrosol, known as Hidrox™ commercially. Some time ago, olive oleuropin, a precursor to hydroxytyrosol was introduced in the US as a dietary supplement. But it is poorly absorbed compared to hydroxytyrosol. Wine: an extract from grapes Consuming grapes, grape juice and raisins promote health. But only wine produces exceptional health qualities. Wine is simply an alcohol extract of grape skins.

Gut 46:191-9, 2000] An antioxidant within olive oil called hydroxytyrosol is believed to provide the colon-cancer preventive effect in olive oil. [European Journal Cancer Prevention 11: 351-58, 2002] Hydrogenated fats, usually found in baked goods, also increase the risk for colon cancer and should be avoided. [Nutrition & Cancer 39: 170-75, 2001] Omega-6 oil, such as provided in corn and safflower oil, is known to enhance the growth of tumor cells, whereas omega-3 oils, such as from fish or flaxseed oil, have the opposite effect. This has also been found specifically for colon cancer.

Handbook of Medicinal Plants Amarjit S. Basra See book keywords and concepts

For example, we have been able to demonstrate that hydroxytyrosol, administered to rats as the only bioactive component of an olive mill waste water extract, is dose-dependently absorbed and is able to increase their plasma antioxidant capacity.27 Furthermore, very low doses of hydroxytyrosol, i.e., 414 g per rat, are able to inhibit passive-smoking-induced oxidative stress in rats, as demonstrated by a reduced urinary excretion of the F2-isoprostane 8-/.vo-PGF2 (iPF2-III).28 Finally, a dose-dependent inhibition of the rate of 8-;.

Triacylglycerols: Hydrocarbons Nonglyceric esters Tocopherols Sterols Polyphenols (50-800 mgkg-1): hydroxytyrosol Oleuropeine Tyrosol Caffeic acid Terpenic acids Pigments Chlorophylls Hydroxytyrosol esters Synaptic acid Syringic acid Vanillic acid Ligstroside Carotenoids temperatures lower than 25 to 30°C yield a high-quality oil that is also rich in phenolic constituents.

O-methyl-transferase (COMT)-derived metabolite of hydroxytyrosol, suggesting that this phenol enters into cellular compartments where it exerts its antioxidant activity.29 CONCLUSION The excessive and unmatched production of free radicals and reactive oxygen species contributes to the onset of certain pathologies such as atherosclerotic heart disease and cancer. This leads to the recommendation of a diet high in fruits and vegetables, in other words, plant food with a large proportion of antioxidant vitamins, flavonoids, and polyphenols.

Furthermore, very low doses of hydroxytyrosol, i.e., 414 g per rat, are able to inhibit passive-smoking-induced oxidative stress in rats, as demonstrated by a reduced urinary excretion of the F2-isoprostane 8-/.vo-PGF2 (iPF2-III).28 Finally, a dose-dependent inhibition of the rate of 8-;.to-PGF2 excretion was observed in human volunteers who ingested olive oils added with increasing amounts of phenolics; interestingly, the urinary levels of 8-i5o-PGF2 inversely correlated with those of homovanillyl alcohol, i.e.

The antioxidant activities of olive oil phenolics, particularly those of the complex phenol oleuropein and its derivative hydroxytyrosol, have been revealed through a variety of experimental cellular and animal models, including transition metal ion- and chemically induced oxidation of LDL and the generation of reactive oxygen species such as superoxide, trichloro-methylperoxyl radicals and hypochlorous acid.24 Further antioxidant activities of olive oil phenolics are their ability to interfere with enzymatic activities relevant to human pathology.

Olive phenol hydroxytyrosol prevents passive smoking-induced oxidative stress, Circulation, 102: 2169-2171. 29. Visioli, F., Caruso, D., Galli, C, Viappiani, S., Galli, G., and Sala, A., 2000, Olive oils rich in natural catecholic phenols decrease isoprostane excretion in humans, Biochem Biophys Res Commun, 278: 797-799; Caruso, D., Visioli, F., Patelli, R., Galli, C, and Galli, G., 2001, Urinary excretion of olive oil phenols and their metabolites in humans, Metabolism, 50: 1426-1428. 30. Mancini, M. and Rubba, P., The Mediterranean diet in Italy, in A.P. Simopoulos and F. Visioli (eds.

Health and Nutrition Secrets Russell L. Blaylock, M.D. See book keywords and concepts

One special flavonoid, called hydroxytyrosol, is especially protective. The typical Western diet is severely deficient in N-3 oils and heavily laden with N-6 oils. The ratio of N-6 to N-3 oils varies from 10:1 to as high as 45:1. It has been estimated that we consume fifty times more N-6 fats than are necessary for good health. Most diets in my native state of Mississippi are in the latter range. Mississippi has the record in gross obesity in the United States and, as a result, extremely high rates of heart attacks, strokes, and cancer.

The New Optimum Nutrition Bible Patrick Holford See book keywords and concepts

My favorite natural anti-inflammatory regime is a combination of omega-3 fats, boswellia, hop extract, hydroxytyrosol from olives, glucosamine, and MSM. Look for combinations of these nutrients and herbal extracts (see Resources). _To keep your bones and joints in good health_ • Keep fit and supple and see an osteopath or chiropractor once a year. Reduce your meat consumption to avoid excessive protein. • Get out of the "stress cycle" and keep stimulants to a minimum. • Make sure your diet is rich in minerals from seeds, nuts, and root vegetables.

One of these is an extract from olives called hydroxytyrosol. This is what is called a polyphenol. Other plant foods containing polyphenols include green tea, grape skins, and onions, all of which contain quercetin, but none is as powerful as this extract of olives. Compared with that of vitamin C, its ORAC rating, a measure of antioxidant power, is more than ten times higher. Try 400 mg a day.

Every_Persons_Guide_To_Antioxidants John R. Smythies See book keywords and concepts

Antioxidant phenols include thymol and carvacuol (thyme), ferulic acid (many herbs), gallic acid (mitgall), hydroxytyrosol (olive oil), fisetin, morin, and many others. Antioxidant polyphenols are found in oranges (as cryptoxanthin) and many other fruits, tea, coffee, chocolate, licorice, and white wine. Other related plant antioxidants include rhein (rhubarb) and aloe-emodin (aloe). Antioxidant peptides (small, proteinlike molecules) include camosine (which is particularly associated with the glutamate receptor in the brain) and anserine.

Olive oil contains a number of antioxidant compounds (including beta-tyrosol, hydroxytyrosol, caffeic acid, and vanillic acid); the concentration of these substances is higher in extra virgin oil than in refined products. The bitter principle of olive oil (oleuropein) also protects LDLs against fat oxidation. A potent phenolic antioxidant in olive oil has the effect of preventing blood platelets from sticking together and reduces the production of inflammation-producing thromboxanes (relatives of prostaglandins).

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