Joerg Gruenwald, Ph.D.
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 Aged garlic extract and its constituents inhibit Cu++-induced oxidative modification of low density lipoproteins. In: PM 63(3):263-264. 1997.
Imai J et al., Antioxidant and radical scavenging effects of aged garlic extracts and its constituents. In: PM 60(5):417. 1994.
Jain AK, Can garlic reduce levels of serum lipids? In: JAMA 94:632-635. 1993.
Jain RC, Vyas CR, (1974) Brit Med J 2:730.
Jung F, Kiesewetter H, Mrowietz C, Pindur G, Heiden M, Miyashita C, Wenzel E, Akutwirkungen eines zusammengesetzten Knoblauchpraparates auf die Fliepfahigkeit des Blutes. In: ZPT 10(3):87. 1989. |
Gary Null and Amy McDonald
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 Aged garlic extract Prolongs Longevity and Improves Spatial Memory Deficit in Senescence-Accelerated Mouse. Moriguchi T; et al. Biological and Pharmaceutical Bulletin, 1996 February, 19(2):305-307.
Results of this study showed that the chronic dietary administration of aged garlic extract improved spatial learning in senescence-accelerated mice.
Ginseng Root Prevents Learning Disability and Neuronal Loss in Gerbils with 5-minute Forebrain Ischemia. Wen TC; et al. Acta Neuropathologica, 1996, 91(l):15-22. |
David W. Grotto, RD, LDN
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 In another study involving 261 patients, those taking garlic extract for sixteen weeks had lowered their cholesterol levels by twelve percent and their triglycerides by seventeen percent. A ten-month study evaluated the effect of aged garlic extract (AGE) on the lipid profiles of men with moderately high cholesterol. Platelet adhesion and fibrinogen (makes blood sticky, increasing risk of clotting) was reduced by approximately thirty percent in subjects taking AGE. |
Jonny Bowden, Ph.D., C.N.S.
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 One recent research article demonstrated the ability of aged garlic extract to inhibit the proliferation of colorectal cancer cells. And yet another study demonstrated the ability of another compound from garlic—diallyl disulfide—to inhibit leukemia cells in a test tube.
Garlic can even help fight the common cold. In one study published in Advances in Natural Therapy, a group of seventy patients was given a high-quality standardized garlic supplement for twelve weeks while another group of seventy-two patients was given a placebo. |
Bill Sardi
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 Various garlic preparations exhibit anti-cancer properties, including fresh crushed garlic cloves, fresh garlic extract, aged garlic, garlic oil, and other sulfur compounds derived from garlic.
The question is, which is the best way to consume garlic: fresh, cooked or aged? [Critical Review Food Science Nutrition 44:479-88, 2004]
Garlic processing
A study was designed to compare several garlic powders with various levels of alii in, a precursor of active sulfur compounds, for their ability to prevent cancer. Rodents were fed diets with three garlic powders with various alliin contents. |
| Current Cancer Drug Targets 3: 67-81, 2003] Aged garlic extract (AGE) has been shown to inhibit both the growth and migration of tumor cells in a laboratory dish. [International J Molecular Medicine 9:641-3, 2002]
In order to confirm the effects of AGE on colon/rectal adenomas (benign epithelial tumors having a glandular origin and structure), researchers provided 2.4 and 0.16 milliliters of AGE per day to patients diagnosed with adenomas. The number and size of these precancerous tumors were determined before and 12 months after intake by direct observation with a colonoscopy. |
C. P. Khare
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 Diallyl disulphide is a constituent that is antibacterial even when diluted to 1:125, 00°-
Due to these active principles, the garlic extract showed antibacterial activity inhibiting the growth of E. coli, Salmonella typhosa, Shigella dysentriae and Micrococcus pyogenes var. aureus.
Scientists were also able to kill Helicobacter pylori by using garlic extract. (H. pylori is considered to be involved in the development of peptic ulcer and stomach cancer.) (Gale Maleskey et al.)
The garlic extract also showed an antifungal effect on yeast and moulds. |
Tori Hudson, N.D.
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 The major growth inhibitory component in garlic extract is allicin, and garlic products that have the highest amount of allicin are the most desirable for treatment. Look specifically for products with high allicin and the stabilized form of allicin. Garlic is diverse in its uses for vaginitis because it is both antibacterial and antifungal.49'50 I recommend garlic vaginal suppositories for both Candida (yeast) vaginitis and bacterial vaginosis. A clove peeled carefully so as not to nick the garlic can be inserted into the vagina for 6 to 8 hours. |
David W. Grotto, RD, LDN
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| A ten-month study evaluated the effect of aged garlic extract (AGE) on the lipid profiles of men with moderately high cholesterol. Platelet adhesion and fibrinogen (makes blood sticky, increasing risk of clotting) was reduced by approximately thirty percent in subjects taking AGE.
REDUCED RISK OF PREECLAMPSIA DURING PREGNANCY: Researchers in London found that garlic may help to boost the birth weight of babies and decrease preeclampsia complications at birth.
CANCER: Nearly thirty studies have shown that garlic has some cancer-preventive effect. |
| The effect of the aged garlic extract, "Kyolic," on the development of experimental atherosclerosis. Arterosclerosis. 1997;132:37-42.
Fleischauer, AT, Arab L. Garlic and cancer: a critical review of the epidemiologic literature. / Nutrition. 2001; 131:1032S-1040S.
Gonzalez C et al. Fruit and vegetable intake and the risk of stomach and oesophagus adenocarcinoma in the European Prospective Investigation into Cancer and
Nutrition (EPIC-EURGAST). Int J Cancer. 2006 May 15;118( 10):2559-2566.
Hsing AW, Chokkalingam AP, Gao YT, et al. |
| Changes in platelet function and susceptibility of lipoproteins to oxidation associated with administration of aged garlic extract. / Cardiovasc Pharmacol. 1998;31:904-908.
Ginger www.mayoclinic.com/heaIth/ginger/NS_patient-ginger; www.umm.edu/altmed/consherbs/gingerch.html#overview
Altman RD and Marcussen KC. Effects of ginger extract on knee pain in patients with osteoarthritis. Arthritis Rheum. 2001 ;44( 11) :2461-2462.
American Association for Cancer Research 97th annual meeting, April 1-5, 2006, Washington, D.C. Study author J. Rebecca Liu, M.D. |
Joerg Gruenwald, Ph.D.
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| Solid garlic extract - an extraction of the chopped bulbs with ethanol or methanol is allowed to evaporate.
Aqueous extract - fresh bulbs are macerated in cold water (1:1).
Fermented garlic - the minced drug is soaked over a long duration in a water-ethanol mixture, volatile agents escape and the garlic becomes odorless. Steam distillations and tinctures are also possible.
Daily Dosage: The average daily dose is 4 gm of fresh garlic or 8 mg of essential oil. One fresh garlic clove, 1 to 2 times daily.
Storage: Garlic should be hung in plaits in a dry place. |
Marshall Editions
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 Take 600 mg of an aged garlic extract twice a day. Passionflower, which can be taken at 250 mg in capsule form or 1 ml in tincture form, helps to decrease blood pressure associated with stress. Dandelion leaf, when taken at 300 mg or 2 ml three times a day, acts as a gentle, natural diuretic to lower blood pressure.
HOMEOPATHY
Due to its chronic nature, high blood pressure is best treated by a combination of complementary and conventional therapies. If mild symptoms have recently developed, consult a homeopathic practitioner as a first resort to bring blood pressure down to a desirable level. |
James F. Balch, M.D. and Mark Stengler, N.D.
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 General Recommendations
Study
Researchers at UCLA Medical Center completed a one-year, double-blind, randomized clinical study with people taking aged garlic extract. Researchers found that people taking aged garlic extract had significantly less coronary plaque formation than did those in the placebo group. Also, the group supplementing the garlic tended to have lower blood homocysteine and cholesterol levels. |
Thomson Healthcare, Inc.
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| Two types of commercial supplements (powdered Garlic and Aged garlic extract) were tested against each other and placebo. The Garlic failed to reduce LDL-C more than 10 mg/dL (0.26 mmol/L) when used for 6 months. In addition, no statistically significant effects were seen with Garlic in terms of HDL-C, triglyceride levels, or the ratio of total cholesterol to HDL-C. Based on various observations made, the authors conclude that Garlic in "reasonable" doses in any form is unlikely to generate lipid benefits (Gardner 2007). |
| Although additional studies are needed, the authors elucidate these possible links and suggest a possible anti-dementia benefit in tandem with heart disease benefits identified with Aged garlic extract (AGE) particularly (Borek 2006).
Hyperlipidemia
Note: There are contradicting results regarding the lipid-lowering effect of Garlic, which may be attributed to lack of manufacturing standardization of the products used in the studies. The fresh Garlic may contain higher amounts of the active ingredient, allicin, which is inactivated upon cooking. |
| The authors concluded that more in-depth and appropriate studies are needed before definitive conclusions or recommendations about garlic's cardio-protective powers in humans can be made (Rahman, 2006)
A small trial examining the effects of Aged garlic extract (AGE) on endothelial dysfunction in people with cardiovascular risk factors or established vascular disease generated mixed results. |
| Atherosclerosis
A pilot trial that evaluated the ability of Aged garlic extract (AGE) to retard the progression of calcification in the coronary arteries found incremental benefits for high-risk patients also on stable statin and aspirin therapy, for example. Nineteen of the 23 patients were enrolled in the placebo-controlled, double-blind, one-year trial. Nine were randomized to take 4 mL of AGE (1200 mg), and 10 to take the equivalent amount of placebo. |
| Regular ingestion of food products containing garlic should not pose a problem. If garlic extract is taken with concomitant use of antiplatelet agents, monitor bleeding time and signs and symptoms of excessive bleeding. Garlic supplements should be discontinued at least 10 days prior to elective surgery (German et al, 1995).
Coleus forskolii: Concurrent use may result in increased risk of bleeding. Clinical Management: Caution is advised in the concomitant use of garlic and Coleus forskolii (forskolin). Regular ingestion of food products containing garlic should not pose a problem. |
| Regular ingestion of food products containing garlic should not pose a problem. If garlic extract is taken with concomitant use of indomethacin, monitor for signs and symptoms of excessive bleeding. Garlic supplements should be discontinued at least 10 days prior to elective surgery.
Thrombolytic agents: Concurrent use may result in increased risk of bleeding. Clinical Management: Concomitant use of garlic and thrombolytic agents is not recommended. Regular ingestion of food products containing small amounts of garlic should not pose a problem. |
Herbert Ross, DC with Keri Brenner, L.Ac.
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 As an alternative to garlic extract, you can also take either liquid garlic (available at health food stores) or fresh garlic cloves.
Caprylic acid, a naturally occurring fatty acid found in coconut oil, has been shown to be an effective antifungal agent. In one study, patients taking 3.6 grams of caprylic acid daily for two weeks completely eliminated their Candida overgrowth. A typical dose is 1 to 2 grams daily, taken with meals. |
Jack Challem
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 A cell study at the Philadelphia Biomedical Research Institute tested the effects of green tea extract and aged garlic extract on sickle-cell dehydration, which exacerbates blood-cell damage and may increase clotting. Epigallocatechin gallate, a major antioxidant component of green tea extract, almost completely inhibited sickle-cell dehydration. The garlic extract reduced dehydration by 30 percent.
Taken together, these studies show that people suffering from sickle-cell anemia risk multiple nutrient deficiencies and often have extremely high vitamin requirements. |
Gary Null and Amy McDonald
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| Results of this study showed that the chronic dietary administration of aged garlic extract improved spatial learning in senescence-accelerated mice.
Ginseng Root Prevents Learning Disability and Neuronal Loss in Gerbils with 5-minute Forebrain Ischemia. Wen TC; et al. Acta Neuropathologica, 1996, 91(l):15-22.
This study examined the neuroprotective effects of ginseng roots in 5-minute ischemic gerbils. Red ginseng powder, crude ginseng saponin, crude ginseng non-saponin, and pure ginsenosides Rbl, Rgl and Ro were administered 7 days prior to ischemia. |
Elaine Magee
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 Studies on a particular form of supplement, AGE (aged garlic extract), have some encouraging results to report. Two small studies from Pennsylvania State University in University Park and UCLA found that AGE reduced total cholesterol by 7 percent and 3 percent, respectively, and reduced LDL cholesterol by 8 percent and 22 percent. |
Gary Null and Amy McDonald
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| The researchers found beneficial effects of aged garlic extract (AGE) and S-allyl cysteine (SAC) on Abeta-induced apoptosis and reactive oxygen species (ROS) generation in a rat cell line.
The Green Tea Polyphenol (-)-Epigallocatechin Gallate Attenuates Beta-Amy-loid-Induced Neurotoxicity in Cultured Hippocampal Neurons. Choi YT; Jung CH. Life Sciences, 2001 December, 21:70(5):603-614.
Green tea polyphenols have protective effects against betaA-induced neuronal apoptosis, which may be beneficial for the prevention of Alzheimer's disease.
Oxidative Stress and Alzheimer Disease. |
Richard Beliveau, Ph.D. and Denis Gingras, Ph.D.
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 Garlic, in particular, seems exceptionally toxic to these cancer cells; even at a one part per thousand dilution, garlic extract succeeds in significantly slowing cancer cell growth (Figure 18).
To summarize, the lowest incidence of cancer in individuals eating the most fruits and vegetables is directly related to the content of these fruits and vegetables in anti-cancer compounds; the presence of these compounds restricts the development of the microtumours that occur spontaneously in our tissues. |
Mike Adams
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 Kyolic Reserve for an aged garlic extract, Coenzyme CIO, Resveratrol, Super EPA / DHA with Sesame Lignans & Olive Fruit Extract, Super Curcumin with Bioperine, Grapeseed Extract with Resveratrol and Blueberry Extract (www.LEF.org)
•* CoffeeBerry (www.NewChapter.info)
Spirulina (www.Cyanotech.com)
Heart Synergy (www.NordicNaturals.com) <•* Baseline Nutritionals Proteolytic Enzymes (www.BaselineNutritionals.com)
Amazon Blood Support (www.Rain-Tree.com)
Carpal Tunnel Syndrome
Carpal Tunnel Syndrome is another so-called disease that doesn't even exist. Certainly the symptoms do exist. |
| Healing foods for high cholesterol
***** fenugreek ***** thyme ***** garlic ***** matsutake ***** wheat grass ***** hawthorn berry ***** dandelion ***** reishi mushroom
Healing herbs for high cholesterol
***** evening primrose oil ***** cod liver oil ***** guar gum ***** kelp ***** psyllium ***** spirulina ***** chlorella
Products to consider for high cholesterol:
•* Fresh blueberries or Blueberry Extract, Policosanol, Kyolic Reserve, an aged garlic extract, Super EPA / DHA with Sesame Lignans and Olive Fruit Extract (www. LEF.org)
<*" GCW Antioxidant Defense System PURPLE (www. |
| Kyolic Reserve, an aged garlic extract, Maitake SX Fraction and Echinacea (www. LEF.org)
Sambucol (www.Sambucol.com) <*" Oregano Force (www.NewChapter.info) <•* Power Immune (www.Fitura.com)
Amazon A-V (www.Rain-Tree.com/amazon-antiviral-support.htm)
Arcozon (http://AmazonDreams.AmazonHerb.net)
SilverlOO colloidal silver (www.SilverlOO.com)
Baseline Nutritionals Super ViraGon (www.BaselineNutritionals.com)
Immune Support Liquid Concentrate (www.Eidon.com) '** DefensePlus (www.NutriBiotic. |
Mike Adams, the Health Ranger
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 I have fresh garlic in huge amounts, as well as garlic extract, just in case anything happens, I have enough for not just myself, but enough for my staff and anyone involved in my life.
Mike: Wonderful. Wonderful advice, and there are products out there, aged garlic as well, and I think Kyolic has a product.
Wolfe: Kyolic has a great product out there.
Mike: So garlic is number one. What is your second?
Wolfe: The second would be echinacea, and echinacea is a flower. It's a traditional kind of Native American herb, very well renowned for its immune system supporting properties. |
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