Jonny Bowden, Ph.D., C.N.S.
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 Think about the popular term for male sexual performance problems—erectile dysfunction, or ED. Coincidentally, ED also stands for endothelial dysfunction—a condition that involves circulatory problems. The two are intimately connected.
"I've never seen a case of erectile dysfunction where there wasn't also endothelial dysfunction," says Mark Houston, M.D., director of the Hypertension Institute in Nashville.
Endothelial dysfunction happens when the inner cells of the blood vessels don't behave properly. |
Dawson Church
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 The EEG readouts demonstrate the regions of their brains that are functioning normally, and those with various degrees of dysfunction. The illustration below indicates the progress made by those subjects that received EFT. It shows that before treatment began, most areas of their brain revealed high or very high levels of dysfunc-tionality Only a small portion of their frontal lobes shows normal or slightly dysfunctional patterning.
Before Treatment of a
Severe Anxiety Disorder After 4 Sessions
..normal ratio of wave frequencies (according to databases)
..slightly dysfunctional ratio
.. |
Jonny Bowden, Ph.D., C.N.S.
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| Endothelial dysfunction is often a predictor of later vascular events like heart attacks and strokes.) What's the connection to sexual performance? Simple: circulation.
"I've almost never seen a case of erectile dysfunction that didn't also have a component of the other ED—endothelial dysfunction," says Mark Houston, M.D. "They frequently go together."
Let's be clear. Impotence has multiple causes. If you're not turned on by your partner, if you're depressed, or if you've got a ton of things on your mind, you may not be in the mood for love. |
Jonny Bowden, Ph.D., C.N.S.
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 Fast-forward a couple thousand years for the kicker: Research published recently in the Journal of Urology examined the long-term intake of pomegranate juice on erectile dysfunction (in an animal model). The results suggest for the first time that free radicals (oxidative stress) are a contributing factor in erectile dysfunction and that due to its powerful antioxidant capabilities, pomegranate juice just may be a "natural Viagra."
Red Wine
Plato may have been on to something when he said, "Nothing more excellent or valuable than wine was ever granted by the gods to man. |
Jonny Bowden, Ph.D., C.N.S.
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| Endothelial dysfunction happens when the inner cells of the blood vessels don't behave properly. It almost always involves problems in circulation and is a great predictor of strokes and heart attacks. Whether in the inner part of the arteries (endothelium) or in the sex organs, poor circulation and impaired blood flow show up as dysfunction—and both are helped greatly by getting your heart pumping and your tissues flooded with blood and nutrients. Plus the improved mood, outlook, and physical appearance that go with regular exercise never hurt anyone in the bedroom department. |
| I've almost never seen a case of erectile dysfunction that didn't also have a component of the other ED—endothelial dysfunction," says Mark Houston, M.D. "They frequently go together."
Let's be clear. Impotence has multiple causes. If you're not turned on by your partner, if you're depressed, or if you've got a ton of things on your mind, you may not be in the mood for love. It's unlikely that horny goat weed, even with maca and L-arginine, are going to make you suddenly fall in lust with Miss Anderson in accounting, particularly if you can't stand her to begin with. |
Shannon Brownlee
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 The choice of the word "dysfunction," writes Parry, "refocused the condition from being associated with a lack of potency (i.e. virility) to the more enlightened concept of physical loss of function that could be simply reversed." All to the good.
What was tricky about condition branding erectile dysfunction was that while the marketing campaign allowed some men to get treated for their flagging sex lives, it undoubtedly caused others to suddenly begin worrying unnecessarily that they had a medical problem. |
Jonny Bowden, Ph.D., C.N.S.
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| And especially in people with high blood pressure, vitamin C improves endothelial dysfunction (a dysfunction of the cells that line the inner surface of all blood vessels) in people with hypertension.
A diet high in fruits and vegetables can do wonders for high blood pressure. So can certain foods. Celery, for example (see page 186) can lower blood pressure when you con- O sume four sticks a day, as can garlic. (For more 03 on how garlic works its magic, see my book The ^
150 Healthiest Foods on Earth. |
Jack Challem
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 Eating foods that are high in sugar, refined carbohydrates, and trans fats induces endothelial dysfunction within minutes, and endothelial dysfunction is common in people with prediabetes, diabetes, and weight problems.
Inflammation is now regarded as the fundamental cause of coronary heart (artery) disease. Chronic low-grade inflammation damages the heart's major blood vessel walls, and the body deposits cholesterol in an effort to protect the arteries. Sustained inflammation weakens the cholesterol deposits, making them more likely to rupture and cause deadly clots in smaller blood vessels. |
| Erectile dysfunction. The inability to maintain an erection is a common complication of prediabetes and more so with full-blown diabetes. Erectile dysfunction may be a sign of more serious circulatory problems.
Early puberty. Although scientists have not figured out exactly why, a high-sugar diet often leads to early puberty in boys and girls. Today, adolescents start puberty at least one year earlier than adolescents did a century ago. It is very likely that high blood-sugar and insulin levels increase the activity of testosterone and estrogen.
Amputation. |
Too Profitable to CureBrent Hoadley, Ph.D.
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| The severity and frequency of hypoglycemic episodes determine the amount of brain dysfunction and concomitant effect on the diabetic.
• Often, if brain dysfunction is severe and outside intervention is unavailable, death or a myriad of other tragic events occur.
We'll now take a look at a few individuals, remembering that it is their dependence on insulin that binds them together as victims.
Justin's Tale
Justin M. began his fateful day just as he had many others. |
Brenda Watson and Leonard Smith
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 Autoimmunity confuses many people, but it's simply an inappropriate immune response to the body's own tissue that can eventually lead to tissue damage and dysfunction. The immune system can become dysfunctional in two ways—overstimulation and suppression. Synthetic chemicals can do both, depending on the specific chemical at hand. An overworked
(overstimulated) immune system, for instance, may prompt the system to turn on itself, activating allergies or autoimmune diseases. |
| They create a heavy burden, triggering a general dysfunction of major systems and body chemistry. Because toxins generally impair the body's ability to function normally, they can be an underlying cause of fatigue, headaches, hormonal imbalances, mood swings, depression, muscle and joint pain, skin conditions, brain fog, problems thinking clearly, neurological dysfunction, low immunity, and much more. This, in turn, opens the door wide open to endless and sometimes life-threatening illness. |
Dr. Timothy Scott
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 Sexual Dysfunction
Sexual dysfunction may impact a larger percentage of antidepressant users than any other symptom. Though the packaging inserts for Prozac and Zoloft report only 2% and 7% of those taking these drugs developing sexual problems, respectively, independent studies suggest much, much higher rates of problems.37 A review of the research that included several randomized, controlled trials (the ideal design for investigating this subject) found that among those taking SSRI antidepressants (which include Prozac and Zoloft), between 30% and 60% experienced sexual dysfunction. |
Melody Petersen
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 The exhibit claimed that "half of all the people in the United States experience some degree of brain dysfunction at some time in their lives." It also explained the cause of this dysfunction. For example, this was its explanation for anxiety: "Chemical imbalances in the brain—often involving the neurotransmitter serotonin—are almost certainly involved."
Pfizer then told visitors to the museum exhibit what they could do about these chemical imbalances. "More medications than ever before are available," it explained. |
Joan Liebmann-Smith, Ph. D., and Jacqueline Nardi Egan
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 And cold intolerance can be a sign of another hormone-related disorder, hypothalamic dysfunction, which affects the hypothalamus, a gland that helps regulate body temperature, appetite, weight, and emotions. Hypothalamic dysfunction can itself be a sign of a tumor, infection, head trauma, or malnutrition.
Feeling cold much of the time can also be a sign that you're anemic. About 20% of people with iron-deficiency anemia suffer from cold intolerance. On rare occasions, sensitivity to cold can be a warning sign of bone cancer or leukemia (cancer of the blood and blood marrow). |
Jack Challem
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| That's because the same nutritional and biochemical problems that cause endothelial dysfunction also lead to erectile dysfunction.
To form an erection, blood vessels in the penis must dilate and fill with blood. This ability of blood vessels to dilate depends on the activity of nitric oxide, a molecule that regulates blood vessel tone. The body makes nitric oxide from L-arginine, a constituent of protein. The conversion of L-arginine to nitric oxide requires the enzyme nitric oxide synthase, which depends on vitamin C. |
Mark Sircus
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 How much of this dysfunction is related to magnesium deficiency is anyone's guess but when upward of 70% of all people are deficient in this precious metal of life it is not too hard to make the connection.
Magnesium and DHEA
DHEA -S levels were significantly lower in the men with sexual dysfunction.7
For normal sexual function, we need both healthy organs and a balanced, working endocrine system, producing the necessary hormones. Cholesterol cannot be synthesized without magnesium and cholesterol is a vital component of many hormones. |
James Dowd and Diane Stafford
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 The longer a patient has had high blood pressure, the higher the uric acid level and the greater the degree of kidney dysfunction. According to statistics, African Americans have more kidney dysfunction stemming from high blood pressure. Furthermore, a person whose kidneys aren't working well has a limited ability to handle dietary acidosis, which contributes to forming uric acid kidney stones.
Why are there more kidney stones today? The answer is urbanization of diets. |
J. Douglas Bremner
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 The Evaluation of Losartan In The Elderly (ELITE II) study randomized 3,152 elderly patients over age sixty with heart failure and left ventricular dysfunction to the ARB losartan or the ACE inhibitor captopril.27 There were no differences in mortality (11.7% vs. 10.4%), although fewer patients stopped medication in the ARB group (9.7% vs. 14.7%), primarily because of dry cough with the ACE inhibitors. These drugs do not help African Americans with left ventricular dysfunction, however.
A recent study in the U.K. followed patients prospectively using a database of 1.18 million patients. |
Mark Sircus
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| Additional symptoms that may be associated with this disease: swallowing difficulty, speech impairment, loss of function or feeling in the muscles, muscle contractions, muscle atrophy, uncoordinated movement, dysfunctional movement, joint pain, hoarseness or changing voice, fatigue, facial paralysis, eyelid drooping, bowel or bladder dysfunction, breathing difficulty. From the National Institutes of Health (NIH) National Library of Medicine (NLM) MEDLINEplus Medical Encyclopedia.
34 WHO, 2002; (www.who.int/mediacentre/factsheets/fsl38/en/print. |
| Marked Elevation of Myocardial Trace Elements in Idiopathic Dilated Cardiomyopathy Compared With Secondary dysfunction. Department of Cardiology, Catholic University, Rome Italy Journal of the American College of Cardiology. Vol. 33, No. 6, 1999, pp. 1578-1583: A large increase (> 10,000 times for mercury and antimony) of TE concentration has been observed in myocardial but not in muscular samples in all patients with IDCM. Patients with secondary cardiac dysfunction had mild increase (<5 times) of myocardial TE and normal muscular TE. |
J. Douglas Bremner
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| ACE inhibitors and ARB drugs have been shown to be helpful if you have what is called left ventricular dysfunction (when your heart is not pumping correctly), or if you have had a heart attack.23-25 The Losartan Intervention For Endpoint Reduction in Hypertension study (LIFE) was conducted in 1,195 patients with high blood pressure, diabetes, and left ventricular failure (heart-pump failure). Patients were given the ARB losartan or the beta-blocker atenolol. This study showed a 26% reduction in fatal and nonfatal strokes and heart attacks with losartan compared to atenolol. |
Michael Pollan
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 Renner documents how Price eventually came to see the problem of diet and health as a problem of ecological dysfunction. By breaking the links among local soils, local foods, and local peoples, the industrial food system disrupted the circular flow of nutrients through the food chain. Whatever the advantages of the new industrial system, it could no longer meet the biochemical requirements of the human body, which, not having had time to adapt, was failing in new ways.
Whether or not you're willing to travel quite that far with Dr. |
Erich Grotewold
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 Moore, et al, 1995) and proinflammatory cytokine-mediated myocardial dysfunction (Ferdinandy et al., 2000; W. Wang et al., 2002). Another potential source of RNS derives from dietary nitrite, which reacts with the acidic gastric juice to produce nitrous acid, which decomposes to oxides of nitrogen. Nitrous acid and its products are able to nitrosate amines, deaminate DNA bases, and nitrate aromatic compounds including tyrosine. |
Tori Hudson, N.D.
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 OVERVIEW OF ALTERNATIVE TREATMENTS
An alternative approach to menstrual cramps due to primary dysmenorrhea needs to provide effective pain relief while at the same time correcting the underlying dysfunction that is creating the pain. Because it is a functional problem and not a disease state that is causing the pain, we can truly focus on a holistic approach by looking for aggravating factors in the diet, lifestyle, environment, and emotional realm. |
| In this context, it is not surprising that in Walberg's study, 86 percent of female competitive bodybuilders not on birth control pills reported menstrual dysfunction, and in Kleiner's, 81 percent of female elite bodybuilders had contest-related amenorrhea for one or two months precontest.
The picture is similar for competitive female runners whose caloric intake is inadequate or falls below the constant energy demanded by their sports. |
| Carotenemia has been linked with menstrual dysfunction and amenorrhea in some women, generally in association with weight loss. In 1968, elevated carotene levels were observed in 9 of 12 women with anorexia nervosa who did not ingest excessive amounts of carotenes.8 An additional study also found that patients with amenorrhea and weight loss had carotenemia.9 Another group of researchers found elevated serum carotene levels in women with anorexia nervosa, but not in women with normal or abnormal menstrual function. |
Benjamin H. Natelson, M.D.
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 Prior to the development of brain magnetic resonance imaging (the well-known test usually called an MRI), MS was diagnosed only if a person had at least two episodes of totally different neurological dysfunction separated in time from each other. The symptom in one episode might be weakness or numbness on one side of the body, while the other episode might involve an experience of double vision due to weakness in the nerves of an eye. But brain MRI has made diagnosing MS simpler. Now a doctor looks at an image that shows the brain from front to back and side to side. |
Michael T. Murray
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 Foot ulcers are common in individuals with diabetes due to the microvascular changes leading to a lack of blood supply, peripheral neuropathy, poor wound healing, and immune system dysfunction leading to chronic infections in the feet. More than 50 percent of cases of lower-limb amputation in the United States (70,000 each year) are due to diabetic foot ulcers.
Immune system dysfunction often begins to occur long before a diagnosis of diabetes is made. In fact, a recurrent vaginal or skin yeast infection is the clue that leads to the detection of diabetes in many cases. |
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