Jonny Bowden, Ph.D., C.N.S. See book keywords and concepts | In a recent article in the Circulation Journal Quly 2004) titled "Effects of green tea intake on the development of coronary artery disease," researchers from the department of medicine at Chiba Hokusoh Hospital, Nippon Medical School, Chiba, Japan, concluded that "the more green tea patients consume, the less likely they are to have coronary artery disease."
Green tea may be helpful for anyone who wants to lose weight. | Russell L. Blaylock, M.D. See book keywords and concepts | Higher levels of this factor predict a lower risk of coronary artery disease.
Apolipoprotein B
This is a primary molecule in LDL structure. Elevated levels are associated with increased cardiovascular disease risk.
Ratio of Apo B/Apo A-l
A high ratio has been associated with a high incidence of coronary artery disease. Several studies have shown that this ratio is particularly valuable in predicting a family history of coronary artery disease.
Fibrinogen
This is a globulin associated with blood coagulation. | Dr. Abram Hoffer, MD, FRCP (C) and Dr. Harold D. Foster, PhD See book keywords and concepts | Anger increases coronary artery disease, premature coronary artery disease, myocardial infarction, and hypertension. These adverse side effects of adrenaline are very dangerous. Contrary activity, which decreases the intensity of such emotions, is therapeutic.
Severe muscular activity and exhaustion depletes the body of adrenaline, and after the 'survival' run, both animals seem to be relatively unconcerned over what has happened. With humans the situation is usually different. | Jonny Bowden, Ph.D., C.N.S. See book keywords and concepts | In a recent article in the Circulation Journal Quly 2004) titled "Effects of green tea intake on the development of coronary artery disease," researchers from the department of medicine at Chiba Hokusoh Hospital, Nippon Medical School, Chiba, Japan, concluded that "the more green tea patients consume, the less likely they are to have coronary artery disease."
Green tea may be helpful for anyone who wants to lose weight. | Shannon Brownlee See book keywords and concepts | The cardiologist performed a stress test, then catheterization, and told Campbell by phone that the patient had severe, three-vessel coronary artery disease and needed immediate bypass surgery. The surgery was done the next day. When Campbell received the written report from her catheterization, two months after her surgery, he was shocked to see that the cardiologist had indicated that the patient had only mild to moderate coronary artery disease and that her chest pain was not caused by her heart. | Joan Liebmann-Smith, Ph. D., and Jacqueline Nardi Egan See book keywords and concepts | PAD is caused by a buildup of fatty plaque in the legs, much like the fat deposits seen in the heart in coronary artery disease (CAD) or the brain in cerebrovascular disease. And like people with CAD, people with PAD are at very increased risk of heart attacks and strokes.
Some other PAD signs are leg cramps when walking and coldness in the extremities. (See Leg Cramps During the Day and Cold Hands and Feet, below.) Having diabetes increases the risk of PAD. | Dr. Steven R. Gundry See book keywords and concepts | Let's start with coronary artery disease, and vascular disease in general, which results from "calluses" accumulating in our blood vessels. Traditional thinking holds that the Western high-fat diet causes fat to stick to our arteries. Maybe so, but why doesn't this fat stick to all of our arteries? Why just the ones in which blockage is lethal or at least incapacitating?
Why are these distinctions important? | Elaine Magee See book keywords and concepts | V4 c walnuts and macadamia nuts: almost 15%
Protein
Folic acid
V4 c peanuts: almost 30% of RDI
1/4 c peanuts: 9 g protein; V4 c Brazil nuts: 5 g; V4 c other nuts: 2-4 g
"Frequent nut consumption is associated with lower rates of coronary artery disease," explains Joan Sabate, MD, MPH, DrPH, a professor of nutrition at the Loma Linda University School of Public Health in California. And according to Dr. Sabate, nut-rich diets improved the cholesterol levels of participants in dietary intervention trials. | Ron Garner See book keywords and concepts | Fat storage around the mid-section, or abdominal obesity, is associated with a high risk of coronary artery disease, which can include high blood pressure, adult onset diabetes, and high levels of fats in the blood.34
An overweight problem can be due to eating too many calories, liver congestion, glandular malfunction, and the fluid that the body retains to dilute toxins. The most offending foods are trans fats and sugars. | Dr. Steven R. Gundry See book keywords and concepts | If you're trying to lose weight, I cannot emphasize too much how important high doses of folic acid and B vitamins in general are in reducing the buildup in your bloodstream of the amino acid homocysteine, which has been directly linked to increased coronary artery disease, stroke, and Alzheimer's disease. A word of warning: More than 300-500 mg of vitamin B6 (pyridoxine) can cause severe neurologic problems. | David W. Grotto, RD, LDN See book keywords and concepts | Effect of an Indo-Mediterranean diet on progression of coronary artery disease in high risk patients. Lancet. 2002; 360:1455-1461. Surette ME, Koumenis IL, Edens MB, Tramposch KM, Clayton B, Bowton D, Chilton FH. Inhibition of leukotriene biosynthesis by a novel dietary fatty acid formulation in patients with atopic asthma: a randomized, placebo-controlled, parallel-group, prospective trial. Clin Ther Mar. 2003; 25(3):972-979.
Suzuki S et al. Daily omega-3 fatty acid intake and depression in Japanese patients with newly diagnosed lung cancer. Br J Cancer. 2004 Feb;23:90(4):787-793. | | Drinking Concord grape juice significantly increased good cholesterol (HDL) and significantly lowered two markers of inflammation in people with stable coronary artery disease.
CANCER: A number of studies have shown a link between grapes and cancer prevention, including the ability to inhibit growth of cancer cells.
Specific cancer types that have been tested include breast, colon, stomach, and leukemia. A rat study found that consumption of Concord grape juice significantly inhibited breast cancer tumor growth. | Dr. Steven R. Gundry See book keywords and concepts | But Lp(a) is such a good spackling compound that it just keeps piling on any damaged area, which means that people with Lp(a) usually develop severe premature coronary artery disease. Why has this gene persisted if it's so lethal? By now you should know. Individuals who carried the gene in vitamin C-sparse areas were able to patch up their leaky blood vessels, enabling them to live long enough to reproduce. Once these individuals had replaced themselves, their genes couldn't care less if they die of a heart attack.
My advice? Get your Lp(a) level measured with a simple blood test. | | So impressive are these "brown" and "green" fats, that when patients with coronary artery disease were given a diet containing 30 percent fat, consisting of canola oil and olive oil enriched with extra ALA, and compared to patients who followed the low-fat American Heart Association (AHA) diet, the trial was halted after three years. Why? Because the results for those in the high green and brown fats group were so dramatically better it was considered unethical to have the others continue on the AHA diet.7 So has the AHA changed its dietary recommendations? No way. | | In fact, a recent Utah study showed that following this last technique just once a month dramatically reduced the development of coronary artery disease in already very healthy Mormons.4 Every time you try one of these options, you'll activate the hormesis response. But please be realistic. Just as you shouldn't be heading down Black Diamond ski runs on your first day on the slopes, these techniques are useful after you have evolved your eating patterns over time. Also, don't abuse these tools in an effort to lose weight. | | If they lose this weight, I can tell they're on track; if not, I'll know some-
Father-Daughter Teamwork
III I I |
I first met Melissa in the hospital waiting room after operating on her 88-year-old grandmother for severe coronary artery disease and a narrowed aortic valve. Grandma was going to be fine, but I didn't like what I saw with Melissa. As a 20-year-old college student, she was 5' 2" tall and weighed more than 300 pounds. Her father, Robert, was also closing in on 300 pounds. Each clenched a large, low-fat Frappuccino. | David W. Grotto, RD, LDN See book keywords and concepts | The antiinflammatory effects of purple grape juice consumption in subjects with stable coronary artery disease. Arterioscler Thromb Vase Biol. 2004 Nov;24(ll):el79-180.
Falchi M et al. Comparison of cardioprotective abilities between the flesh and skin of grapes. J Agric Food Chem. 2006 Sep 6;54(18):6613-6622.
Fuhrman B, Volkova N, Coleman R, Aviram M. (2006, August). Grape powder polyphenols attenuate atherosclerosis development in apolipoprotein E deficient (E0) mice and reduce macrophage afherogenicity./Nutr. 136(8), 2272.
Jung KJ, Wallig MA, Singletary KW. (2006, February). | Tom Bohager See book keywords and concepts | Contributing factors include stress, obesity, poor diet and eating habits, family history, gallbladder disease, and coronary artery disease.
Typically, individuals with diverticulosis do not have physical symptoms, but symptoms can include tenderness on the left side of the abdomen that is relieved by a bowel movement or passage of gas, cramping, nausea, or constipation or diarrhea.
Diverticulitis can develop from diverticulosis. Diverticulitis is a condition in which the diverticula become inflamed, are perforated, or rupture. Tissue surrounding the colon can become infected. | David W. Grotto, RD, LDN See book keywords and concepts | Cereal fiber and whole-grain intake are associated with reduced progression of coronary-artery atherosclerosis in postmenopausal women with coronary artery disease. Am Heart J. 2005; 150:94-101.
Ruibal-Mendieta NL et al. Spelt (Triticum aestivum ssp. spelta) as a source of bread-making flours and bran naturally enriched in oleic acid and minerals but not phytic acid. JAgric Food Chem. 2005 Apr 6;53(7):2751-2759.
Ruibal-Mendieta NL et al. Spelt (Triticum spelta L.) and winter wheat (Triticum aestivum L. | Jonny Bowden, Ph.D., C.N.S. See book keywords and concepts | Carnitine also appears to really improve exercise capacity in people with coronary artery disease. In one study, the walking capacity of patients with intermittent claudication—a painful cramping sensation in the muscles of the legs due to decreased oxygen supply—improved significantly when they were given oral L-carnitine. In another study, patients with peripheral arterial disease of the legs were able to increase their walking distance by ninety-eight meters when supplemented with carnitine, almost twice what those given a placebo were able to do. | Thomson Healthcare, Inc. See book keywords and concepts | Dwivedi S, Jauhari R, Beneficial effects of Terminalia arjuna in coronary artery disease. Indian Heart J, 49:507-10, 1997 Sep-Oct.
Hansel R, Keller K, Rimpler H, Schneider G (Ed), Hagers Handbuch der Pharmazeutischen Praxis, 5. Aufl., Bde 4-6 (Drogen), Springer Verlag Berlin, Heidelberg, New York, 1992-1994.
Kandil EE, Nassar MI, A tannin anti-cancer promoter from Terminalia arjuna. Phytochemistry, 53:1567-8, 1998 Apr.
Kaur S, Graver IS, Kumar S, Antimutagenic potential of ellagic acid isolated from Terminalia arjuna. Indian J Exp Biol, 53:478-82, 1997 May. | | Another study mentioned in the review found that oral administration of vitamin C reversed endothelial vasomotor dysfunction in patients with coronary artery disease (CAD), with benefits observed after 30 days (Witte and Clark, 2006).
Discrepancies exist between studies of subjects with adequate plasma levels of vitamin C and those obtaining vitamin C from diet or supplementation. For example, in a 2005 review, several studies with conflicting results are mentioned. | | Morita H, Tagushi J, Kurihara H et al: Genetic polymorphism of 5, 10-methylenetetrahydrofolate reductase (MTHFR) as a risk factor for coronary artery disease. Circulation; 95(8):2032-2036. 1997
Morgan SL, Oster RA, Lee JY et al. The effect of folic acid and folinic acid supplements on purine metabolism in methotrexate-treated rheumatoid arthritis. Arthritis & Rheumatism; 50(10):3104-3111. 2004
Mulinaire J: Epidemiologic associations of multivitamin supplementation and occurrence of neural tube defects. Ann N Y Acad Sci; 678:130-136. | Ann M. Coulston and Carol J. Boushey See book keywords and concepts | Cholesteryl ester transfer protein concentration is associated with progression of atherosclerosis and response to pravastatin in men with coronary artery disease (REGRESS). Eur. J. Clin. Invest. 34, 21-28.
245. Thompson, J. F., Wood, L. S., Pickering, E. H., Dechairo, B., and Hyde, C. L. (2007). High-density genotyping and functional SNP localization in the CETP gene. J. Lipid Res. 48, 434-443.
246. Barter, P. J., Brewer, H. B. Jr., Chapman, M. J., Hennekens, C. H., Rader, D. J., and Tall, A. R. (2003). | | Association of small low-density lipoprotein particles with the incidence of coronary artery disease in men and women. JAMA 276, 875-881.
82. Stampfer, M. J., Krauss, R. M., Ma, J., Blanche, P. H., Holl, L. G., Sacks, F. M., and Hennekens, C. H. (1996). A prospective study of triglyceride level, low-density lipoprotein particle diameter, and risk of myocardial infarction. JAMA 276, 882-888.
83. Reaven, G. M. (1988). 1988 Banting Lecture: Role of insulin resistance in human disease. Diabetes 37, 1595-1607.
84. Despres, J. P., Lamarch, B., Mauriege, P., Cantin, B., Dage-nais, G. R. | Hyla Cass, M.D. See book keywords and concepts | D-ribose can boost heart function in those with coronary artery disease, hypertension, and those on statins. It also is useful for treating fibromyalgia, where there are pains all over due to lack of oxygen in the muscles and surrounding tissue. Athletes, especially marathon runners, love it. Combine your D-ribose with L-carnitine (see page 131) and CoQ10 for a great boost in energy.
Caution: Since D-ribose can lower blood sugar, diabetics need to monitor their insulin levels when taking it. | Ann M. Coulston and Carol J. Boushey See book keywords and concepts | Plasma levels of plant sterols and the risk of coronary artery disease: The prospective EPIC-Norfolk Population Study. J. Lipid Res. 48, 139-144.
234. Devaraj, S., and Jialal, I. (2006). The role of dietary supplementation with plant sterols and stands in the prevention of cardiovascular disease. Nutr. Rev. 64, 348-354.
235. Hendriks, H. F., Brink, E. J., Meijer, G. W., Princen, H. M., and Ntanios, F. Y. (2003). Safety of long-term consumption of plant sterol esters-enriched spread. Eur. J. Clin. Nutr. 57, 681-692.
236. Homma, Y., Ikeda, I., Ishikawa, T., Tateno, M., Sugano, M. | | Antioxidant nutrient supplementation reduces the susceptibility of low density lipoprotein to oxidation in patients with coronary artery disease. J. Am. Coll, Cardiol. 30, 392-399.
70. Field, C. J. (2000). Use of T cell function to determine the effect of physiologically active food components. Am. J. Clin. Nutr. 71(6 suppl), 1720S-1750S.
71. Lourd, B., and Mazari, L. (1999). Nutrition and immunity in the elderly. Proc. Nutr. Soc. 58, 685-695.
72. Murata, T., Tamai, H., Morinobu, T. M. M., Takenaka, H., Hayashi, K., and Mino, M. (1994). | Tom Bohager See book keywords and concepts | Elevated triglyceride levels have been associated with coronary artery disease.
Recommendations for lowering triglyceride levels include dietary changes to lower fat intake and regular exercise. Enzymes can be used to improve digestion, particularly the digestion of fats; improve the breakdown of fats in the body; and improve cardiovascular health. |
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