Jonny Bowden, Ph.D., C.N.S.
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 It was the ability of arthritis drugs like Vioxx and Celebrex to inhibit COX-2 that made them effective. Unfortunately, at least in the case of Vioxx, side effects were dangerous enough to cause it to be withdrawn from the market. Anthocyanins have no such side effects. Though the anthocyanin content in strawberries isn't as high as that in cherries or raspberries, it's still significant. And anthocyanins have significant antioxidant activity as well.
A cup of strawberries has only about 50 calories and delivers about 3 g of fiber. |
Andreas Moritz
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 Steroids, arthritis drugs, and NSAID's
A medical investigation in the United States has shown that three times more people die from legal prescription drugs than from illegal narcotic drugs, such as heroin and cocaine. This study does not account for the contra-indications of the drugs, which kill at least 30,000 a year in the U.S. These are people who take medications, but have conditions (including drug allergies) that would cause these drugs to be dangerous for them. |
| In the same context, COX-2 inhibitors—prescription arthritis drugs designed to be safer than NSAIDS— have been found to actually raise heart attack risk and cause strokes.
Based on the results from these studies, the treatment of heart failure should not involve the use of drug-based blood thinners, such as aspirin. It is relatively easy to keep the blood thin through a balanced vegetarian diet, drinking sufficient quantities of water, avoiding diuretic foods and beverages, keeping regular mealtimes and bedtimes, and cleansing the liver, kidneys and colon. |
| Stroke, heart attack, blood clots in the lung, deep vein blood clots in the leg, all can result just from taking this drug. arthritis drugs have never been properly tested for safety. Vioxx, Celebrex, Bextra, Aleve, and aspirin are just plain poisons. Another arthritis drug, infliximab (Remicade), is on alert for causing cancer.
Amazingly, many people have been so blinded by clever advertising campaigns and brainwashing that they have no clue they are being methodically poisoned in order to support and sustain the most lucrative business in the world besides oil, the pharma-medical industry. |
Jonny Bowden, Ph.D., C.N.S.
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| The popularity of arthritis drugs like Vioxx and Celebrex was based on their unique ability to block only the pain and inflammation messages of COX-2 while leaving the noninflammatory COX-1 alone. Unfortunately, there were some really unpleasant side effects associated with Vioxx, and it was taken off the market. But anthocyanins produce a similar effect with none of the problems of drugs. Cherries (and raspberries) have the highest yields of pure anthocyanins. In one study, the COX inhibitory activity of anthocyanins from cherries was comparable to those of ibuprofen and naproxen. |
Jonny Bowden, Ph.D., C.N.S.
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 Some years ago, a popular class of arthritis drugs was developed that were known as COX-2 inhibitors; they inhibited the pain-signaling COX-2 molecules without touching the non-inflammatory COX-Is. The problem was, there were some really serious side effects with some of these drugs—such as the increased risk of blood clotting and heart attack—and at least one, Vioxx, was taken off the market. But anthocyanins produce a similar effect with none of the side effects.
Cherries (and raspberries) have the highest yields of pure anthocyanins. |
Mike Adams, the Health Ranger
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 If people knew the truth about the anti-inflammatory benefits of cherries, the sales of arthritis drugs would plummet...)
In talking to the CEO of FruitFast, I learned they were about to launch a nationwide radio advertising campaign to offer this 30-day supply of their CherryFlex product to the public. Through phone negotiations, I was able to encourage the FruitFast company to hold off on their national radio advertising campaign and, instead, reserve 20,000 bottles of CherryFlex exclusively for NewsTarget readers! But this offer is only good for the next few days, while supplies last. |
Mike Adams, the Health Ranger
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 Chemotherapy doesn't work, antidepressant drugs cause weight gain, diabetes drugs cause liver damage, statin drugs damage the heart, antipsychotic drugs caused suicidal behavior, arthritis drugs cause heart attacks, blood pressure drugs cause circulation deficiencies... need I go on? There's hardly a popular drug in the arsenal of Big Pharma that isn't fraudulently marketed, promoted and prescribed. |
Jonny Bowden, Ph.D., C.N.S.
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| It was the ability of arthritis drugs like Vioxx and Celebrex to inhibit COX-2 that made them effective. Unfortunately, at least in the case of Vioxx, side effects were dangerous enough to cause it to be withdrawn from the market. Anthocyanins have no such side effects.
Research conducted at Michigan State University investigated a range of fruits and berries for the level and activity of anthocyanins found in each. The yield of pure anthocyanins in raspberries was the second highest of all the fruits tested (cherries were first, but not by much). |
Mike Adams, the Health Ranger
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 You'll get a dose of antidepressants, antibiotics and arthritis drugs with every smooth sip! And if that thought makes you shudder, don't sweat it, there are also anti-convulsants in the water. Perhaps this is what allows Los Angeles residents to handle the traffic there.
I just wonder, with all the drugs in the water, will you soon need a prescription to drink it? Will drug companies charge royalties for drinking the water? Will Bush take credit for it and explain this was his plan all along to provide "free drugs" to voters? |
Joe Graedon, M.S. and Teresa Graedon, Ph.D.
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 Aspirin is one of the most common culprits, but many other arthritis drugs can also contribute to the problem. If you suspect that a medicine is causing ringing, hissing, or whooshing, please discuss this with your physician promptly.
Drug-Induced Tinnitus • • •
Q. / am desperate to find some way to alleviate my arthritis pain without experiencing unbearable tinnitus. I have taken aspirin for some time, and it has been quite effective. If a joint flares up, I increase the dose for a few days. Then I heard your radio show where you mentioned that aspirin can contribute to tinnitus. |
Leslie Taylor, ND
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 Richard Rutter, noted Peruvian ethnobotanist, insists that iporuru is wide-
PLANT CHEMICALS
BIOLOGICAL ACTIVITIES AND CLINICAL RESEARCH
Scientists are just learning how iporuru reduces inflammation in research with animals: a mechanism similar to several leading arthritis drugs. ly used as an effective aphrodisiac and geriatric tonic for males. Throughout Peru it is regarded as a remedy for impotency as well as for balancing blood sugar levels in diabetics. |
| COX-1 inhibitors are a new (and highly profitable) class of arthritis drugs being sold today by pharmaceutical companies. Another research group in Brazil documented significant antiinflammatory effects in rats using various models,15-17 and researchers in 2002 noted a significant pain-relieving effect in rats.18 The pain-relieving and antiinflammatory effects were even verified when an ethanol extract was applied topically in rats, again validating traditional use. |
Greg Critser
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 The advisory committee charged with arthritis drugs looked at the rate of Arava-linked liver injury reported in the FDA's adverse-event reporting system (AERS) and found the risk-benefit ratio of the drug to be "acceptable." Graham undertook the same evaluation — and more — and disagreed. Citing the fact that only 1 to 10 percent of severe adverse events are ever reported to the agency in the first place, he performed a complex calculation showing that Arava's rate of injury was likely much higher. Then he got even more aggressive. |
Joe Graedon, M.S. and Teresa Graedon, Ph.D.
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| Dietary Supplements
With all the bad news about prescription arthritis drugs it is hardly any wonder that dietary supplements have become hugely successful in the health-food stores. In fact, they have jumped from the fruit-and-nut locales to the pharmacy and even big-box discount stores like Wal-Mart and Costco. Sales of glucosamine and chondroitin have been spectacular, exceeding $700 million annually. Can it last? |
| Aspirin and other arthritis drugs (nonsteroidal antiinflammatory drugs, or NSAIDs, like naproxen and ibuprofen) can cause ringing in the ears. |
H. Winter Griffith, M.D.
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 May be used alone or in combination with certain other arthritis drugs.
DOSAGE & USAGE INFORMATION
How to take:
Injection—The drug is self-injected under the skin (subcutaneously). Follow your doctor's instructions and the directions provided with the prescription on how and where to inject. Do not use the medication unless you are sure about the proper method for injection. Store medication in the refrigerator (do not freeze) until you plan to use it. After each use, throw away the syringe and any medicine left in it (ask your pharmacist about disposal methods). |
| May be used alone or in combination with certain other arthritis drugs (e.g., methotrexate).
Treats Crohn's disease, moderate to severe ankylosing spondylitis, and psoriatic arthritis. May be used for other disorders as determined by your doctor.
DOSAGE & USAGE INFORMATION
How to take:
• Etanercept and adalimumab injection—The drug may be self-injected under the skin (subcutaneously). Follow your doctor's instructions and the directions provided with the prescription on how and where to inject. Do not use the medication unless you are sure about the proper method for injection. |
Marcia Angell, M.D.
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 A study sponsored by the drug company that makes it, Pharmacia (since acquired by Pfizer), ostensibly showed that Celebrex caused fewer side effects than two older arthritis drugs. These results were published, along with a favorable editorial, in The Journal of the American Medical Association. Not until after publication did the editors learn that the results were based on only the first six months of a yearlong trial. When the entire trial was analyzed, there was no advantage to Celebrex. The editorialist was understandably outraged. The Washington Post quoted him as saying, "I am furious. . |
Bill Gottlieb
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 A nutrient that can stop the body-hurting side effects of the most commonly used arthritis drugs ... An herbal cocktail that can end a case of the flu fast... A food supplement that can prevent a hangover (just take a teaspoon before going to bed) . . . An aromatherapy spray that can keep you from getting carsick ... A supplement paste that can minimize blistering of poison ivy and poison oak, so you hardly know you have it.
Plus: An herb that can help stop the capillary damage of diabetes . . . An acupressure "neck release" that can help speed the healing of bursitis ... |
Earl Mindell, R.Ph., Ph.D.
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 Indian studies have shown that curcumin is as strong an anti-inflammatory as many of the arthritis drugs sold by prescription and over the counter. In fact, in double-blind studies with arthritis patients, curcumin produced significant improvement comparable with phenylbutazone, a prescription nonsteroidal anti-inflammatory (NSAID) medication. The advantage of curcumin over the NSAID is that there are no known side effects, while NSAIDs in general can cause stomach distress, bleeding ulcers, and other problems. |
The Editors of Prevention Magazine Health Books
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 Several substances can increase your need for the vitamin, including alcohol, tobacco, aspirin and other nonsteroidal anti-inflammatory drugs, oral contraceptives, pancreatic extracts, estrogen, antacids, arthritis drugs such as methotrexate and medications prescribed for convulsions, malaria and bacterial infections.
Iron
Daily Value: 18 milligrams
Qood Food Sources: Beef, Cream of Wheat cereal, baked potatoes, soybeans, pumpkin seeds, clams
' 1 here's no doubt that many of us can use more iron than we're getting. Roughly 20 percent of Americans are deficient in this mineral. |
Michael T. Murray, N.D., Joseph E. Pizzorno, N.D.
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 Head-to-head studies using arthritis drugs have shown that glucosamine sulfate produces better results without side effects.
• Chondroitin sulfate and cartilage preparations are poorly absorbed.
• Physical therapy and exercise can help relieve osteoarthritis.
• Topically applied menthol or capsaicin preparations can help reduce the pain of osteoarthritis. osteoarthritis are given no treatment. One group of researchers studied the natural course of osteoarthritis of the hip over a ten-year period. |
the Editors of PREVENTION
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 Research on newer, better arthritis drugs is ongoing and incredibly promising. For now, though, it's standard practice for doctors to prescribe one of the many nonsteroidal anti-inflammatory drugs (NSAIDs) to ease the pain and inflammation of rheumatoid arthritis, says Dr. Lisse. For osteoarthritis, they start with acetaminophen to relieve pain, but if that doesn't work, they go on to NSAIDs.
The problem is that while NSAIDs may mask the pain, they can and do cause intestinal bleeding that lands thousands of people in the hospital each year. |
Joe Graedon and Teresa Graedon
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 For the interaction of anticoagulants with other arthritis drugs, see page 257.
INSTRUCTIONS
Aspirin may be taken with food or milk to reduce stomach upset, always with a full eight ounces of liquid. Pregnant women should take aspirin only under the doctor's supervision. Children with flu or chickenpox must avoid aspirin because it increases the risk of Reye's syndrome.
INTERACTION
Both aspirin and warfarin are effective anticlotting agents, although they work through different pathways. Large doses of aspirin can significantly increase bleeding in people taking warfarin. |
Russell L. Blaylock, M.D.
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 These include most of the commonly used arthritis drugs such as ibuprofen. Glucocorticoids are some of the most powerful eicosanoid blocking drugs known. By blocking "bad" eicosanoid production, one bypasses the negative effects of interfering with normal glutamate function. Unfortunately, the available drugs do not selectively block all of the "bad" eicosanoids. One group of particularly bad eicosanoids, called leukotrienes, are not blocked. |
Joe Graedon and Teresa Graedon
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| Other arthritis drugs may also interact. Symptoms of Heart and Kidney Problems
Notify your doctor of sudden weight gain, swollen legs and feet, change in the color of the urine, unusual back pain, fatigue, cough, or breathlessness. Elevated serum creatinine may mean kidney trouble. Monitor blood pressure frequently.
Never take or stop medication without your doctor's advice. |
| NTERACTION
Some of the arthritis drugs on this list can drastically diminish the effectiveness of blood pressure medicines such as Capoten and Vasotec. Indocin can wipe out the blood-pressure-lowering power of these drugs; ibuprofen can interact similarly with Capoten. Even aspirin given with or before Vasotec can reduce that drug's benefit for treating congestive heart failure. |
| Antifungal Drug
Diflucan
Aspirin and arthritis drugs (salicylates)
Cholesterol Drug
Lopid
Cortisonelike Drugs
Aristocort Cortef cortisone Decadron Kenacort etc.
Diuretics
Dyazide HydroDIURIL etc.
LEVELS OF HAZARD: life threatening dangerous troublesome
Diabetes Drugs
Phenylbutazone brand name
Diabinese
Dymelor
Orinase generic name chlorpropamide acetohexamide tolbutamide
DESCRIPTION
These pills are prescribed for non-insulin-dependent diabetics. |
| Other arthritis drugs may also interact. Symptoms of Heart and Kidney Problems
Notify your doctor of sudden weight gain, swollen legs and feet, change in the color of the urine, unusual back pain, fatigue, cough, or breathlessness. Elevated serum creatinine may mean kidney trouble. Monitor blood pressure frequently.
Never take or stop medication without your doctor's advice. |
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