Mike Adams, the Health Ranger
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 REPPED: This is part three of our investigative report into Hoodia Gordonii, a natural appetite suppressant. (If you missed part 2, click here to read it.) In this part, we're exploring how hoodia works to control appetite and actually help people lose weight. Understanding hoodia is easier when you consider your own weight loss goals: how much easier do you think losing weight would be if you didn't have to battle hunger?
For most people, that's the whole solution right there. Turn off the hunger and almost anybody can lose weight. |
Mike Adams, the Health Ranger
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 Now imagine what you could achieve in terms of weight loss by taking advantage of this natural appetite suppressant. That's exactly what we'll discuss in the next installment of this investigative report series on Hoodia Gordonii.
Continue with part 3. |
Jonny Bowden, Ph.D., C.N.S.
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 The scientists working on the product reasoned that if you could trick your body into releasing CCK before a meal, you'd have a natural appetite suppressant.
While there have certainly been other "appetite suppressants" on the market, many intestinal injury in addition to protecting against gut permeability. Researchers have also found that zinc carnosine encourages cells to travel to a simulated wound area and trigger increased cell proliferation, suggesting that zinc carnosine improves wound healing. |
Mike Adams, the Health Ranger
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| This is why eating an apple is such an effective appetite suppressant.
Normally, to get your hypothalamus to turn off the hunger switch, you'd have to eat a moderate amount of food. And your hypothalamus isn't very quick on the draw either: it takes around 20 minutes to figure out what you've eaten, and by that time, you've probably eaten another 800 calories. So by the time your hunger signal gets turned off, you've already overeaten yet again.
This chemical fools your hypothalamus
Hoodia, however, contains a chemical that gets picked up by your hypothalamus which thinks it's glucose. |
Thomson Healthcare, Inc.
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 Unproven Uses: Hoodia gordonii is traditionally used in South Africa for its appetite suppressant properties. Paradoxically, it is also used as appetite stimulant. Hoodiais also used for indigestion, hypertension, diabetes, stomachache, abdominal pain, and peptic ulceration. contraindications
None are known. precautions and adverse reactions
No reliable information is available. Safety in pregnancy and nursing has not been established. drug interactions
No human drug information is available. dosage
No information is available. |
| New oxypregnane glycosides from appetite suppressant herbal supplement Hoodia gordonii. Steroids. 2007 Jun;72(6-7):524-34.
Rader JI, Delmonte P, Trucksess MW. Recent studies on selected botanical dietary supplement ingredients. Anal Bioanal Chem. 2007 Mar 28.
Van Wyk B-E, Gericke N (2000) People's Plants: a guide to useful plants of southern Africa. Briza Publications, Pretoria. |
| Hypertensive crisis resulting from an MAO inhibitor and an over-the-counter appetite suppressant. Ann Emerg Med; 11:482-484. 1982.
Theoharides TC. Sudden death of a healthy college student related to ephedrine toxicity from a ma huang-containing drink. J Clin Psychopharmacol. Oct;17(5):437-439. 1997.
Tinkelman DG & Avner SE. Ephedrine therapy in asthmatic children: clinical tolerance and absence of side effects. JAMA; 237:553. 1977.
Tokola O, Laitinen LA, Aho J et al: Drug treatment of motion sickness: scopolamine alone and combined with ephedrine in real and simulated situations. |
Gary Null and Amy McDonald
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 Phenylalanine is also an appetite suppressant for many people. If they're given correctly there seems to be no toxicity associated with amino acids and they're much cheaper than antidepressants or anti-anxiety prescription medications."
Dr. Walt Stoll has a different approach: "In my clinical experience, I have found that emotional disorders are often linked to the inability to completely break down proteins, during the digestive process, into their amino acids. |
Jonny Bowden, Ph.D., C.N.S.
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 A cup of lentil soup as an appetizer is a great natural appetite suppressant.
8. Sea vegetables: These are rich in minerals and are great at detoxifying heavy metals and pesticides. They are also very alkalizing and can help offset the acid load from the Standard American Diet of grains, meats, and dairy. These might seem a little scary at first, but they are great to sprinkle on a salad, soup, or veggie dish, or you can always visit a Japanese restaurant a few times a week for some nori-wrapped delicacies.
9. |
Mike Adams, the Health Ranger
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 It is sad that this mess overshadows the other part of the question, which is whether or not hoodia gordonii works as an appetite suppressant even if you have the real thing. Because there has been so much counterfeiting and so much adulterated hoodia being sold to consumers, most people who have used hoodia didn't notice any effect. They think that hoodia doesn't work, but they probably weren't taking real hoodia in the first place.
I believe that hoodia holds potential for being a highly effective appetite suppressant. |
Marshall Editions
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 Hoodia: The sap or the roots and stems of hoodia have traditionally been used as an appetite suppressant, which may be due to a compound called P57AS3. Research into the positive effects of this plant and compound is still in the early stages so it is too soon to tell if this plant will live up to its reputation.
PIN WORMS
DIAGNOSIS
Pinworms are the most common type of parasitic infection of the intestines. Contrary to popular belief, they are not carried by household pets. The white, thread-like worms are about 0.4 inches (1 cm) long and live in the bowel. |
Brigitte Mars, A.H.G.
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 Also Known As
English: Brazilian cocoa, uabano, uaranazeiro German: kletterstrauch Guarani: wara'na Tupi: wara'na
Part Used
Seed
Physiological Effects
Analgesic, antibacterial, antioxidant, aphrodisiac, appetite suppressant, astringent, carminative, diuretic, febrifuge, hyperglycemic, refrigerant, stimulant, thermogenic, vasodilator
Medicinal Uses
Guarana has about two and a half times the caffeine content of coffee; however, it is absorbed more slowly into the gastrointestinal tract, so it has a gentler, longer-lasting effect. |
Thomson Healthcare, Inc.
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| Determination of the appetite suppressant P57 in Hoodia gordonii plant extracts and dietary supplements by liquid chromatography/electrospray ionization mass spectrometry (LC-MSD-TOF) and LC-UV methods. J AOAC Int. 2006 May-Jun;89(3):606-ll.
Dall'acqua S, Innocenti G. Steroidal glycosides from Hoodia gordonii. Steroids. 2007 Jun;72(6-7):559-68. Epub 2007 Mar 27.
MacLean DB, Luo LG. Increased ATP content/production in the hypothalamus may be a signal for energy-sensing of satiety: studies of the anorectic mechanism of a plant steroidal glycoside. Brain Res. 2004 Sep 10; 1020(1-2): 1-11. |
Ann M. Coulston and Carol J. Boushey
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 Drugs should also be considered, but whether currently available drug therapies, such as the appetite suppressant, sibutramine, or an inhibitor of fat absorption, orlistat, are more or less effective in individuals with single-gene obesity than those with polygenic obesity is unknown. However, as with any severe obesity, when lifestyle changes and pharmaceutical approaches are inadequate to ameliorate morbidity, surgical treatment of the obesity may be considered. |
Thomson Healthcare, Inc.
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| P57AS3 (P57), an oxypregnane steroidal glycoside, is the only reported active constituent from this plant as an appetite suppressant. Intracerebroventricular (i.e.v.) injections of the purified P57AS3 demonstrated that the compound has a likely central (CNS) mechanism of action. There is no evidence of P57AS3 binding to or altering activity of known receptors or proteins, including Na/K-ATPase, the putative target of cardiac glycosides. The compound increases the content of ATP by 50-150% in hypothalamic neurons. In addition, third ventricle (i.e.v. |
Phyllis A. Balch, CNC
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 Fennel removes mucus and fat from the intestinal tract and is a natural appetite suppressant.
þ Fenugreek is useful for dissolving fat within the liver.
þ Gotu kola aids in reducing body mass and aids in adrenal processes that facilitate carbohydrate metabolism. It also increases energy.
Q Guarana and kola nut are appetite suppressants.
Q Guggul, an ancient Ayurvedic herbal remedy, helps to normalize blood cholesterol and triglyceride levels. It also has a mildly stimulating effect on the thyroid. |
Craig Pepin-Donat
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 Cold remedies like Sudafed® and decongestants like AcuTrim®, which is also used as an appetite suppressant, contain stimulants that boost physical performance. They can also cause heart palpitations, weight loss, hypertension, hallucinations and convulsions.20
The athletic field isn't the only place where people are looking to improve performance. While middle-aged men across the country leapt at the chance to take prescription drugs like Viagra®, Cialis® or Levitra® to improve sexual performance, others looked to more natural supplements like horny goat weed. |
| One of the most popular ingredients to hit the supplement scene is the appetite suppressant Hoodia gordonii, a cactus found in the Kalahari Desert. The story the manufacturers are pitching is that Hoodia is eaten by African Bushmen to control their hunger as they travel through the desert. Now this is the stuff of sales and marketing legend. Surely, if it comes from a far-off, mysterious land and works for the Bushmen, it will work in our toxic, overstuffed society. Some manufacturers even suggest that the nonexistent rate of obesity in indigenous populations is a result of eating Hoodia. |
Michael T. Murray and Michael R. Lyon
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 Moderate to intense exercise may have an appetite suppressant effect. þIndividuals who exercise during and after weight reduction are better able to maintain the weight loss than those who do not exercise. þExercise helps diminish anxiety and reduces depression, two major factors that drive people to the refrigerator in their search to find a sense of comfort.
While the immediate effect of exercise is stress on the body, with regular exercise the body adapts; it becomes stronger, functions more efficiently, and has greater endurance. |
Mike Adams, the Health Ranger
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 In my view, hoodia is listed here more for marketing purposes than as a highly effective appetite suppressant. I think the glucomannan is going to be a far better appetite suppressant than the hoodia gordonii found in this formula.
So, let's move on to the next ingredient, and that is sodium carboxymethylcellulose. This is also present at 100 mg, and it's another form of fiber that takes up space in your stomach, makes you feel full, and helps lower the effective glycemic index of other foods you consume.
The next ingredient we have is glucosamine HCL. |
Brenda Davis and Tom Barnard
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 Chickweed is also used as an appetite suppressant. As far as appetite suppressants go, it is among the least harmful. Garcinia cambogia is another rising star in the weight loss world. It is used as both an appetite suppressant and a fat burner, and appears quite harmless.
Fat Blockers
The most popular "natural" fat blocker is chitosan, which is derived from chitin, a complex starch found in the exoskeleton of shellfish such as shrimp, lobster, and crabs. Like Xenical, it can reduce the absorption of fat-soluble vitamins and phytochemicals, very possibly doing more harm than good. |
Bottom Line Health
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| Nausea may occur but it's usually temporary.
Mistake 4: Not eating andA>r exercising properly. These two factors are the cornerstones of diabetes prevention and management. If people who are at risk for diabetes eat nutritiously and lose as little as 5% to 10% of body weight, they are better able to use their natural insulin to remove glucose from the blood.
Exercise is equally important. Prediabetics who engage in 30 minutes of moderate-intensity aerobic exercise five days per week can reduce their risk of progressing to diabetes by 58%. |
Mike Adams, the Health Ranger
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 That's right: water is a powerful appetite suppressant and if you drink an 8-ounce glass of water when you first start feeling hungry, you will find that it suppresses your appetite in nearly every case. If you just drink a full glass of water and have the discipline to wait 10 minutes, you will find that your appetite is either completely gone or dramatically reduced.
Your next choice, if water does not do the trick for you, is to purchase a 32-ounce quart of natural, organic vegetable broth. |
| You can also extend the effect of this by taking appetite suppressant supplements. Hoodia gordonii is one I've reviewed quite extensively, and it is currently increasing in popularity. My own experience is that hoodia tincture can help, but even hoodia doesn't shut off appetite completely.
Also, you don't want to starve yourself by eating these 100-calorie meals all day long. Remember, starvation is the fastest way to train your body to hold on to body fat. These are just items to get you past a difficult time when your appetite is unbearably intense. |
Mike Adams, the Health Ranger
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| I think the glucomannan is going to be a far better appetite suppressant than the hoodia gordonii found in this formula.
So, let's move on to the next ingredient, and that is sodium carboxymethylcellulose. This is also present at 100 mg, and it's another form of fiber that takes up space in your stomach, makes you feel full, and helps lower the effective glycemic index of other foods you consume.
The next ingredient we have is glucosamine HCL. This glucosamine works to lower the effective glycemic index of whatever carbohydrates you may have eaten. |
by Michael Murray, N.D. and Joseph Pizzorno, N.D.
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| Moderate to intense exercise may have an appetite suppressant effect.
• Individuals who exercise during and after weight reduction are better able to maintain the weight loss than those who do not exercise.
• Exercise helps diminish anxiety, and it reduces depression—two major factors that often lead to stress-induced eating to find a sense of comfort.
Osteoarthritis
Osteoarthritis (OA), also known as degenerative joint disease, is a form of arthritis (inflammation of a joint) caused by degeneration of cartilage. Cartilage serves an important role in joint function. |
Mike Adams, the Health Ranger
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| That alone makes you feel more full, which turns off the hunger signals in your brain, effectively making Trim Spa an appetite suppressant. It means you'll eat less at a meal if you take Trim Spa before the meal, and if you take several tablets of Trim Spa, you will have even more glucomannan in your stomach, meaning you have even less space remaining for foods that would add calories to your diet. And that's another point about glucomannan -- it has no calories whatsoever. It's just a fiber. It's just something that takes up space, like swallowing a giant water sponge. |
Jonny Bowden, M.A., C.N.S.
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 It's another appetite suppressant that few docs are using these days, but it is hawked on my friendly local Internet pharmacy for $99 per month.
Benzphetamine
A schedule 3 controlled substance, benzphetamine is closely related to amphetamine and has a high potential for abuse. The brand name commonly seen is Didrex. It's highly addictive and very expensive. One Internet site sells it for $99 a month. Avoid it like the plague.
All of these medications except phentermine are somewhat old-fashioned and are rarely used these days. Phentermine, however, remains very popular. |
H. Winter Griffith, M.D.
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 Appetite suppressants*
Decreased appetite suppressant effect.
Barbiturates*
Oversedation.
Carteolol
Decreased antihistamine effect.
Central nervous system (CNS) depressants*
Dangerous degree of sedation.
Cisapride
Decreased antihistamine effect.
Clozapine
Toxic effect on the central nervous system.
Continued on page 904 n
POSSIBLE INTERACTION WITH OTHER SUBSTANCES
INTERACTS WITH
COMBINED EFFECT
Alcohol:
Dangerous oversedation.
Beverages:
None expected.
Cocaine:
Decreased trimeprazine effect. Avoid.
Foods:
None expected.
Marijuana:
Drowsiness.
Tobacco:
None expected. |
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