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PYY3-36 appetite control nasal spray may be effective, yet still misused by consumers

Mike Adams, the Health Ranger
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This is similar to the promise of the herbal-based, appetite control suppressant known as 'Hoodia'. It’s from the Hoodia Gordonii succulent and it is now widely sold as capsules or tinctures for appetite control. This is the promise of the Nastech PYY3-36 Nasal Spray, and it is potentially a very promising treatment for obesity (and would even help those with diabetes as well). In fact, this could potentially become a huge success as a prescription drug. It could be a blockbuster seller.

Hunger Free Forever: The New Science of Appetite Control

Michael T. Murray and Michael R. Lyon
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Unfortunately, in overweight and obese individuals, this complex system of appetite control becomes altered. As a result, they possess an increased appetite drive along with frequent and excessive food cravings. They become more sensitive to both internal and external signals to eat, and they are less able to experience a strong sense of satiety when they have eaten adequate amounts of food.
People without weight problems benefit from a complex and properly working system of appetite control composed of compounds that circulate in the blood such as various hormones, peptides, neurotransmitters, and glucose, all of which are sensed and acted upon by the brain. People of normal weight don't tend to experience frequent and unhealthy food cravings, and they usually feel hungry at appropriate times. They are also inclined to feel satisfied when they have eaten modest-sized food portions that don't promote weight gain.
Because it appears the diet drinks confuse the appetite control centers to trigger hunger rather than promote satiety. health with dramatically increased rates of obesity, type 2 diabetes, and virtually ever other chronic disease. IS OBESITY INHERITED? Yes and no. While there is no actual "fat gene," virtually all of us have inherited a powerful tendency toward obesity. It actually begins at the moment of conception as the genetic code from our parents combine. This tendency is mostly in the form of survival mechanisms built into our normal physiology.
Much of the effect of blood sugar fluctuations on appetite control can be traced to specialized immune cells, called glial cells, that surround every brain cell. Glial cells are important in sensing the level of glucose in the blood. Every time blood sugar drops rapidly in a short span of time, glial cells send powerful signals to brain regions such as the hypothalamus, which are interpreted as a desire to initiate food intake. Because of insulin resistance and its accompanying poor glucose regulation, overweight people spend their days riding a virtual blood sugar roller coaster.
Think of the appetite control center having an "off button for appetite that will only respond to insulin. With insulin resistance, the appetite never really gets shut down. Insulin Resistance and Blood Sugar Control Obviously one of the key abnormalities in insulin-resistant individuals is their loss of precise control over blood sugar. To a large extent because of their frequently increased blood sugar levels, these "diabetics in training" experience the same kinds of accelerated aging and tissue damage that occurs in diabetics, but at a slower pace.

Five appetite control foods that suppress cravings without adding calories

Mike Adams, the Health Ranger
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Emergency appetite control food #2 The next best strategy is to turn to green vegetables such as lettuce, cabbage, bokchoy, and other leafy vegetables. They have so few calories that in my own diet, I don't even count them. That's right: I allow myself to eat an unlimited quantity of any green leafy vegetables without even recording the number of calories I have consumed. In my book, they are "free" foods. It takes just as many calories for your body to digest them as you get out of the foods themselves.
Emergency appetite control food #5: Here's an easy one: apples. Yep, apples. Eat the largest apple you can find. Sure, you'll get some calories and some carbs, but the apple will fill you up for quite a while, and that will stop you from eating far more calorie-dense foods. Let me explain why this is such an effective strategy. If you're crazy hungry, it's very easy to reach for some processed foods (bag of chips, for example) and start munching away until you've consumed 1000 calories or more. And that's about half the total calories you need for the entire day!
Emergency appetite control food #1 Fresh drinking water. That's right: water is a powerful appetite suppressant and if you drink an 8-ounce glass of water when you first start feeling hungry, you will find that it suppresses your appetite in nearly every case. If you just drink a full glass of water and have the discipline to wait 10 minutes, you will find that your appetite is either completely gone or dramatically reduced. Your next choice, if water does not do the trick for you, is to purchase a 32-ounce quart of natural, organic vegetable broth.
Emergency appetite control food #4: The last food is pickles. That's right, pickles. But I am not talking about the pickles you find at a regular grocery store. Nearly all pickles you find in grocery stores contain artificial food coloring. They have a yellowish tint to them that has been added through the use of chemical colors. This is not a natural ingredient and so it is something you want to avoid purchasing.
Emergency appetite control food #3 This is one of my favorites: I call it my "instant banana pudding" recipe, but of course, it's nothing at all like store-bought pudding. You'll need a blender for this one. Add a quart of soy milk to the blender, then a couple of scoops of unsweetened banana-flavored simply natural spirutein soy protein powder. (Sources are listed in the downloadable book, "Secret Sources." Add stevia powder as the sweetener.

PYY3-36 appetite control nasal spray may be effective, yet still misused by consumers

Mike Adams, the Health Ranger
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In this article, I will be discussing the PYY3-36 appetite control Nasal Spray made by a company called Nastech. This is an upcoming prescription drug product still in Phase II testing that could someday offer tremendous potential to help people lose weight. But it's not all smooth sailing yet; there are some potential dangers and pitfalls along the way. Those will be discussed here as well. The first thing to realize about this Nastech product is that it's not really a prescription drug at all, in my view.
It’s from the Hoodia Gordonii succulent and it is now widely sold as capsules or tinctures for appetite control. This is the promise of the Nastech PYY3-36 Nasal Spray, and it is potentially a very promising treatment for obesity (and would even help those with diabetes as well). In fact, this could potentially become a huge success as a prescription drug. It could be a blockbuster seller. But now let's look at some of the problems this product could bring to the forefront if it becomes a huge success.

Hunger Free Forever: The New Science of Appetite Control

Michael T. Murray and Michael R. Lyon
See book keywords and concepts
Perhaps the biggest impact of increased food volume as it leads to reduced caloric intake relates to its effect on producing distension of the stomach. In fact, the air in Dr. Rolls's milkshakes (see "The Satiety Effect of Air," page 67) produced greater distension of the stomach and therefore influenced subjective responses related to hunger and appetite. In both animal and human studies, the degree of gastric distension is known to affect food intake, particularly by effecting the feeling that you have had enough.

The 150 Healthiest Foods on Earth: The Surprising, Unbiased Truth About What You Should Eat and Why

Jonny Bowden, Ph.D., C.N.S.
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Hence melons and soups do a better job of appetite control than solid food plus a glass of water. No one really knows why.) Cantaloupe Lowers the Risk of High Blood Pressure and Stroke But cantaloupe's not a great food just because it's high-volume and low-calorie, though that certainly gives it points. It's also a potassium and vitamin A heavyweight. One little cup of melon cubes gives you a whopping 427 mg of potassium (not to mention a little calcium and magnesium). A ton of studies show that people who eat potassium-rich foods have lower rates of heart disease and stroke.

Nutrition in the Prevention and Treatment of Disease

Ann M. Coulston and Carol J. Boushey
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Variability of appetite control mechanisms in response to 9 weeks of progressive overfeeding in humans. Int. J. Obes. 30, 1160-1162. 8. Hull, H. R., Radley, D., Dinger, M. K., and Fields, D. A. (2006). The effect of the Thanksgiving Holiday on weight gain. Nutr. J. 5, 1-6. 9. Hull, H. R., Hester, C. N., and Fields, D. A. (2006). The effect of the Holiday season on body weight and composition in college students. Nutr. Metab. 3, 44-50. 10. Van Staveren, W. A., Deurenberg, P., Burema, J., DeGroot, L. C, and Hautvast, J. G. (1986).
Various mechanisms through which genetic susceptibility to weight gain have been proposed include low resting metabolic rate, low level of lipid oxidation rate, low fat-free mass, and poor appetite control [36]. Genetic research holds considerable promise for understanding the development of obesity and identifying those at risk for obesity. However, the rapid increase in rates of obesity has occurred over too brief a time period for there to have been significant genetic changes in the population.

The Feel-Good Diet

Cheryle Hart, M.D., and Mary Kay Grossman, RD
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The symptoms most improved were appetite control, mood, anger, fatigue, muscle pain, and sleep. These studies show the importance of supplementing amino acid precursors to raise serotonin and dopamine levels. The sublingual delivery system is easier to follow and more efficient with fewer side effects. Study 1: Clinical Symptom Improvement Study Forty-two clients were followed over five weeks while using neurotransmitter supplement lozenges. Participants completed a fifty-one-point questionnaire relating to common signs and symptoms of serotonin and dopamine deficiencies.

Superfoods Rx Diet: Lose Weight with the Power of SuperNutrients

Wendy Bazilian, DRPH, MA, RD, Steven Pratt, MD, Kathy Matthews
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Leptin resistance makes appetite control a continuing challenge. Chronically elevated Cortisol in conjunction with adrenaline can also encourage your body to hold on to fat,3 and lead to elevated insulin levels or insulin resistance thereby favoring fat storage, particularly around the abdomen. These complex interactions throw yet other obstacles before you as you try to reduce fat and inches in, on and around your body. High Cortisol levels stimulated by stressful situations can also play a contributing role in bone loss over time. So how do you deal with stress?

The Food-Mood Connection: Nutrition-based and Environmental Approaches to Mental Health and Physical Wellbeing

Gary Null and Amy McDonald
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In the hypothalamus, there is loss of temperature and appetite control. It also affects the pituitary gland, the thyroid, adrenals, and sex hormones and stress reactions." Food Addiction_ Food addictions and food cravings often mask food allergies. Dr. Hyla Cass describes her experience treating patients suffering from food addiction as follows: "Some time ago, a psychologist who specializes in eating disorders began to send her clients to me because she had heard that antidepressant medications worked for these patients.

Many "natural" foods contain questionable taste additives like yeast extract

Mike Adams, the Health Ranger
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That's because MSG harms the normal function of your endocrine system and it disrupts your appetite control system. So even though you may be physically full from eating, your brain tells you you're still hungry and you overeat. If you've ever felt like you are eating unhealthy foods but couldn't stop eating them, it could be because you've been poisoning yourself with MSG. If you stop consuming foods with MSG, you may be able to rebalance this natural system and return to healthy, normal appetite control.

Processed Meat Unsafe For Human Consumption; Cancer Experts Warn of Dietary Dangers

Mike Adams, the Health Ranger
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MSG is a dangerous excitotoxin linked to neurological disorders such as migraine headaches, Alzheimer's disease, loss of appetite control, obesity and many other serious health conditions. Manufacturers use MSG to add flavor to dead-tasting processed meat products. Essentially, dead meat products look and taste dead (because they are), so meat companies use the following three ingredients to make them look fresh and taste interesting: Sodium nitrite makes the meat look red and fresh. (But it promotes cancer.) MSG makes the meat taste savory. (But it causes neurological disorders.

The 150 Healthiest Foods on Earth: The Surprising, Unbiased Truth About What You Should Eat and Why

Jonny Bowden, Ph.D., C.N.S.
See book keywords and concepts
Hence melons and soups do a better job of appetite control than solid food plus a glass of water. No one really knows why.) But honeydew's not a great food just because it's high-volume and low-calorie, though that certainly gives it points. It's also a potassium and vitamin A heavyweight. One little cup of melon balls gives you a whopping 404 mg of potassium (not to mention a little calcium and magnesium and 31 mg of vitamin C). A ton of studies show that people who eat potassium-rich foods have lower rates of heart disease and stroke.
Pennsylvania State University, has done a ton of research on appetite and appetite control. In study after study, Rolls found that people basically ate about 3 pounds of food a day, regardless of whether the food was high calorie or low calorie. After about 3 pounds, people stopped eating. They'd eat nearly identical servings of food (by weight), whether it was watermelon (high volume) or cheesecake (low volume).

Nutrition in the Prevention and Treatment of Disease

Ann M. Coulston and Carol J. Boushey
See book keywords and concepts
Replacement of dietary fat with sucrose polyester: Effects on energy intake and appetite control in nonobese males. Am. J. Clin. Nutr. 63, 891-896. 154. Kelly, S. M., Shorthouse, M., Cotterell, J. C, et al. (1998). A 3-month, double-blind, controlled trial of feeding with sucrose polyester in human volunteers. Br. J. Nutr. 80, 41-49. 155. Blundell, J. E., and Hill, A. J. (1986). Paradoxical effects of an intense sweetener (aspartame) on appetite. Lancet 1, 1092-1093. 156. Stellman, S. D., and Garfinkel, L. (1986). Artificial sweetener use and one-year weight change among women. Prev. Med.

The 150 Healthiest Foods on Earth: The Surprising, Unbiased Truth About What You Should Eat and Why

Jonny Bowden, Ph.D., C.N.S.
See book keywords and concepts
Pennsylvania State University, has done a ton of research on appetite and appetite control. In study after study, Rolls found that people basically ate about 3 pounds of food a day, regardless of whether the food was high calorie or low calorie. After about 3 pounds, people stopped eating. They'd eat nearly identical servings of food (by weight), whether it was honeydew (high volume) or cheesecake (low volume). Most important, the subjects in her studies felt just as full after the low-calorie meals as they did after the calorie-rich meals— provided both meals contained the same volume of food.

The Most Effective Natural Cures on Earth: The Surprising, Unbiased Truth about What Treatments Work and Why

Jonny Bowden, Ph.D., C.N.S.
See book keywords and concepts
Perhaps the most remarkable result was in appetite control," Preuss says. "The placebo group had no change, but the HCA group had a 16 percent reduction in the amount of food they ate per meal!" Remember, besides using the right form of HCA, you have to use the right dosage. Preuss and his research team have determined that the ideal dose for weight loss is likely to be about 2,800 mg a day of HCA. Super CitriMax (also known as HCA-SX) for example, is 60 percent HCA.

Superfoods Rx Diet: Lose Weight with the Power of SuperNutrients

Wendy Bazilian, DRPH, MA, RD, Steven Pratt, MD, Kathy Matthews
See book keywords and concepts
Here's another point to consider: Nuts, when added to a weight-reduction diet like the SuperFoodsRx Diet, seem not only to promote more weight loss and more permanent weight loss but also seem to improve insulin sensitivity,34 which could certainly be a factor in nuts' ability to help with appetite control and resulting weight loss. So there's no question that walnuts and their sidekicks are excellent additions to your SuperFoodsRx Diet for two reasons: They'll help you maintain your good health and, believe it or not, they'll help you lose weight.

101 Foods That Could Save Your Life!

David W. Grotto, RD, LDN
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And buckwheat studies with humans also are showing promise—for appetite control. A study in 2005 found that people felt fuller after consuming buckwheat compared to other grains. Tips on Using Buckwheat SELECTION AND STORAGE: • Bulk buckwheat should be free from condensation, clumping, or "webbing," a sure indication of pest infestation. • When buying prepackaged buckwheat, check the expiration date and make sure the bag is free of moisture. • Buckwheat can be stored up to a year in an airtight container if kept in a cool, dry place.

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This unique compilation of research is copyright (c) 2008 by the non-profit Consumer Wellness Center.

ABOUT THE CREATOR OF NATURALPEDIA: Mike Adams, the creator of this NaturalNews Naturalpedia, is the editor of NaturalNews.com, the internet's top natural health news site, creator of the Honest Food Guide (www.HonestFoodGuide.org), a free downloadable consumer food guide based on natural health principles, author of Grocery Warning, The 7 Laws of Nutrition, Natural Health Solutions, and many other books available at www.TruthPublishing.com, creator of the earth-friendly EcoLEDs company (www.EcoLEDs.com) that manufactures energy-efficient LED lighting products, founder of Arial Software (www.ArialSoftware.com), a permission e-mail technology company, creator of the CounterThink Cartoon series (www.NaturalNews.com/index-cartoons.html) and author of over 1,500 articles, interviews, special reports and reference guides available at www.NaturalNews.com. Adams' personal philosophy and health statistics are available at www.HealthRanger.org.

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