Kelly Patricia O'Meara See book keywords and concepts | Novartis Pharmaceuticals Website "Clinical pharmacology."
11 Novartis Pharmaceuticals Website "Antidepressant Medications."
12 Shire Pharmaceuticals Website AdderallXR "Causes of ADHD." http://www. adderallxr.com.
13 Food and Drug Administration Website "Clinical Pharmacology" AdderallXR.
14 "Lilly Announces Important Strattera Label Update" September 29, 2005, Lilly Strattera Website, htlp://newsroom.lilly.com.
15 Food and Drug Administration Website "Clinical Pharmacology" Strattera, http://www.fda.gov. | Gary Null and Amy McDonald See book keywords and concepts | Department of Clinical and Experimental Medicine and pharmacology, Section of pharmacology, University of Messina, Messina, Italy. espina@unime.it J Clin Psychopharmacol. 2002 Aug;22(4):419-23
The effect of fluoxetine on the steady-state plasma concentrations of risperidone and its active metabolite 9-hydroxyrisperidone (9-OH-risperidone) was evaluated in 10 patients with schizophrenia or schizoaffective disorder. Patients stabilized on risperidone (4-6 mg/day) received additional fluoxetine (20 mg/day) to treat concomitant depression. | Melody Petersen See book keywords and concepts | The nation's academic pharmacologists held these pill peddlers in such low esteem that they refused to allow any industrial scientist to become a member of the American Society for pharmacology and Experimental Therapeutics, which had been founded by Dr. John Jacob Abel. Dr. Abel operated a laboratory at Johns Hopkins University and is widely regarded as the father of American pharmacology.
"It is well known that the advertisers of drugs and medicines have often failed to confine their statements to actual facts," Dr. | Ann N. Martin See book keywords and concepts | Medical schools often use dogs to teach basic physiology and pharmacology. Nancy Harrison, MD, from the association, Doctors Against Dog Labs, writes, "In dog labs, students or instructors typically anesthetize a dog, cut open the dog's chest and use its beating heart to demonstrate principles of physiology and pharmacology. At the end of the demonstrarion, they kill the dog."2 Dr. Harrison explains, "Like other concerned physicians, I am working to persuade the medical school I care most about? | Connie Bennett, C.H.H.C. with Stephen T. Sinatra, M.D. See book keywords and concepts | Amphetamine-Sensitized Rats Show Sugar-Induced Hyperactivity (Cross-Sensitization) and
Sugar Hyperphagia." pharmacology, Biochemistry and Behavior 74, no. 3 (2003): 635-39.
Barnard, Neal. Breaking the Food Seduction. New York: St. Martin's Press, 2003.
BBC. "Fast Food 'as Addictive as Heroin.' " BBC website.
Blum, Kenneth, E. P. Noble, P. J. Sheridan, A. Montgomery, T. Ritchie, P. Jagadeeswaran, H. Nogami, A. H. Briggs, and J. B. Cohn. "Allelic Association of Human Dopamine D2 Receptor Gene in Alcoholism." Journal of the American Medical Association 263, no. 15 (1990): 2055-60. | Joerg Gruenwald, Ph.D. See book keywords and concepts | ACTIONS AND pharmacology compounds
Volatile oil (0.5-0.9%): chief components 1,8-cineole, alpha-and beta-pinene, p-cymene
Tannins (4%)
Resins (7%)
Hydroquinone glycosides: arbutin (0.2-0.7%) Cyanogenic glycosides: tetraphylline B (barterin)
INDICATIONS AND USAGE
Damiana preparations are used as an aphrodisiac and for prophylaxis and treatment of sexual disturbances.
PRECAUTIONS AND ADVERSE REACTIONS
No health hazards or side effects are known in conjunction with the proper administration of designated therapeutic dosages.
LITERATURE
Auterhoff H, Haufel HP, (1968) Arch Pharm 301:537. | | In experimental pharmacology, aconitin is used due to its ability to trigger cardiac arrhythmia.
PRECAUTIONS AND ADVERSE REACTIONS
The drug is highly toxic. Signs of poisoning can appear even with the administration of therapeutic dosages. The first sign of poisoning is a tingling of the mouth as well as of the fingers and toes, that then spreads over the entire body surface and changes into a furry sensation. Body temperature falls heavily. Queasiness, vomiting, diarrhea and urination occur. | | Further information in:
Chan H, But P (Eds.), pharmacology and Applications of Chinese Materia Medica, Vol 1, Ed. World Scientific Singapore 1986.
Frohne D, Pfander HJ, Giftpflanzen - Ein Handbuch fur Apotheker, Toxikologen und Biologen, 4. Aufl., Wiss. Verlags-Ges Stuttgart 1997.
Hansel R, Keller K, Rimpler H, Schneider G (Hrsg.), Hagers Handbuch der Pharmazeutischen Praxis, 5. Aufl., Bde 4-6 (Drogen), Springer Verlag Berlin, Heidelberg, New York, 1992-1994.
Lewin L, Gifte und Vergiftungen, 6. Aufl., Nachdruck, Haug Verlag, Heidelberg 1992. | | Chemistry, Biology, pharmacology and Clinical Perspectives. Vol II, JR Prous Science, Barcelona 1989.
Bruchert E, Heinrich SE, Ruf-Kohler P, (1991) Wirksamkeit von LI 1370 bei alteren Patienten mit Hirnleistungsschwache. Munch Med Wschr 133(Suppl 1):9-14.
Bundesgesundheitsamt, (1991) Empfehlungen zum Wirksamkeitsnachweis von Nootropika im Indikationsbereich "Demenz" (Phase LTT). Bundesgesundheitsblatt 7:342-350.
Caesar W, Alles iiber Ginkgo. In: DAZ 134(44):4363. 1994.
Delia Loggia R, Sosa S, Tubaro A, Bombardelli E, Antiinflammatory activity of Ginkgo biloba flavonoids. In: PM 59(7):A588. | | Not To Be Confused With: Linden flower should not be confused with Tilia tometosa and Tilia x euchlora
Other Names: Lime, Linn Flowers
ACTIONS AND pharmacology compounds: tiliae carbo
Extremely adsorbent charcoals effects: tiliae carbo
No information is available. compounds: tiliae folium
Flavonoids: including, among others, linarin (acacetin-7-rutinosides)
Tannins
Mucilage effects: tiliae folium
No information is available. | Thomson Healthcare, Inc. See book keywords and concepts | Other Names: Sweet Wood Bark, Sweet Bark, Bahama Cascarilla actions and pharmacology compounds
Volatile oil (1.5 to 3%): chief components are p-cymene, limonene, alpha-thujone, pinenes, linalool, myrcene, terpeni-nol-4
Diterpene bitter principles: including Cascarillin A (15%) Resins (25%) effects
Cascarilla is a stimulant and a tonic. indications and usage
Unproven Uses: Cascarilla is used for digestive disorders, diarrhea, and vomiting. precautions and adverse reactions
Health risks or side effects following the proper administration of designated therapeutic dosages are not recorded. | C. W. Randolph, M.D. See book keywords and concepts | Based on my background in pharmacology and medical tiaining, I developed a holistic approach to treat this condition of estrogen dominance. The approach has three components:
1. A diet specifically designed to reduce the body's estrogen levels.
2. Natural hormone replacement therapy to restore hormone equilibrium.
3. A select list of vitamins and supplements that have been proven to work synergistically to support optimal hormone balance. the results
After following the plan, hormone balance was restored in all of my patients, and their symptoms of estrogen dominance disappeared. | Joerg Gruenwald, Ph.D. See book keywords and concepts | Egan D, O'Kennedy R, Moran E, Cox D, Prosser E, Thornes RD, The pharmacology, metabolism, analysis, and applications of coumarin and coumarin-related compounds. In: Drug Metabolism Reviews 22(5):503-529. 1990.
Ellinger A, Zur pharmako-dynamischen Charakterisierung des Cumarins. In: Schmiedebergs Arch exp Pathol Pharmakol Suppl. Festschrift, S. 150-163. 1908.
Fentem JH, Fry JR, Thomas NW, Species differences in the hepatotoxicity of coumarin - a comparision of rat and Mongolian gerbil. In: Toxicology 71(1-2):129. 1992. | Marshall Editions See book keywords and concepts | Much of modern-day pharmacology owes a debt to herbal medicine as many of the drugs available to Western physicians are derived from plants that have a long history of use as herbal remedies. Opinions on acceptable doses of herbs to ingest, and the appropriate quantity of plant material to use to make an infusion or decoction, vary. Dosage depends on a patient's specific symptom and its severity, personal taste, and/or the form of the plant available (for example, fresh versus dried plant material). | Connie Bennett, C.H.H.C. with Stephen T. Sinatra, M.D. See book keywords and concepts | Doctors prescribed medications to help her cope—a litany of drugs that reads like a pharmacology manual: Zoloft, Depakote, Risperidol, Imipramine, Klonopin, BuSpar, Paxil, Trazodone, Ativan, and Ambien. But the meds helped to bring about another problem. In a year and a half, the 5-foot, 10-inch Stephanie ballooned from "anorexic looking" to 215 pounds. | Thomson Healthcare, Inc. See book keywords and concepts | Recent studies on the zoopharmacognosy, pharmacology and neurotoxicology of sesquiterpene lactones. Planta Med; 61:199-203. 1995
Schaffner W. Granny's remedy explained at the molecular level: helenalin inhibits NF-kappaB. Biol Chem; 378(9): 935. 1997
Schmidt Th J et al. Sesquiterpen lactones and inositol esters from Arnica angustifolia. In: PM 61(6): 544-550. 1995
Schroder H, Losche W, Strobach H et al. Helenalin and 11-alpha, 13-dihydrohelenalin, two constituents from Arnica montana L., inhibit human platelet function via thiol-dependent pathways. Thromb Res; 57:839-845. | Jonny Bowden, Ph.D., C.N.S. See book keywords and concepts | A new study in Alimentary pharmacology & Therapeutics showed that taking antibiotics to kill H. pylori, along with medication to control stomach acid, has an 86 percent success rate, but when zinc carnosine is added to the mix, the success rate climbs to a perfect 100 percent.
NSAIDs, which also include pain relievers such as aspirin and aspirin-like compounds like ibuprofen and naproxen sodium, aren't as innocuous as they seem. | Paula Begoun and Bryan Barron See book keywords and concepts | Other sources for this article: Current Molecular Medicine, March 2005, pages 171-177; Applied Spectroscopy, July 1998, pages 1001-1007; Skin Research and Technology, November 2003, pages 306-311; Journal of the American Academy of Dermatology, March 2003, pages 352-358; Skin pharmacology and Applied Skin Physiology, November-December 1999, pages 344-351; and Dermatology, February 2005, pages 128-134.)
Essential Point: All of the elements above are prime factors that contribute to making what I (and many cosmetic ingredient researchers and chemists) consider a state-of-the-art moisturizer. | Dr. Jonathan Prousky, BPHE, BSc, ND, FRSH See book keywords and concepts | Introduction to the pharmacology of CNS drugs. In Katzung BG (ed.). Basic & Clinical pharmacology. 6th ed. Norwalk, CT: Appleton & Lange. 1995:330.
2. Braverman ER, Pfeiffer CC, Blum K, et al. The Healing Nutrients Within. 2nd ed. New Canaan, CT, Keats Publishing, i997;246-47,247-58, 290-303.
3. Mitchell WA Jr. Foundations of Natural Therapeutics: Biochemical Apologetics of Naturopathic Medicine. Tempe, AZ: Southwest College Press, 1997^05-08.
4. Daigle RD, Clark HW, Landry MIM. A primer on neurotransmitters and cocaine. J Psychoactive Drugs 1988;20:283-95.
5. Hoes MJ, Colla P, Folgering N. | Tori Hudson, N.D. See book keywords and concepts | In another study examining the pharmacology of vitex (another term for chaste tree), serum prolactin levels were reduced via vitex's natural prolactin-suppressive compounds, namely diter-penes. These diterpenes have dopaminergic properties and bind to the DA2-receptor protein, which, in turn, suppressed prolactin release.15
Chaste tree is the most important herb to normalize and regulate the menstrual cycle. Chaste tree is not a fast-acting herb; do not hesitate to use it over a long period of time. In fact, results may not be achieved until after four to six months. | Jonny Bowden, Ph.D., C.N.S. See book keywords and concepts | Hyperforin, rather than hypericin as originally thought, has emerged as one of the major constituents for antidepressant activity," one 2001 article in the Journal of Pharmacy and pharmacology pointed out.
The rich cast of active plant chemicals is undoubtedly why St. John's Wort has been found useful for such a wide variety of conditions besides depression. In fact, the Physician's Desk Reference for Herbal Medicine lists positive results in clinical trials for anxiety, cognitive function, fatigue, ear pain in children, dermatitis, and PMS, in addition to depression. | Erich Grotewold See book keywords and concepts | Shoei-Yn Lin-Shiau, Institute of pharmacology, College of Medicine, National Taiwan University for her inspiring discussion during the preparation of this article.
8. REFERENCES
Afaq, F., Adhami, V. M, Ahmad, N, and Mukhtar, H, 2003, Inhibition of ultraviolet B-mediated activation of nuclear factor KB in normal human epidermal keratinocytes by green tea constituent (-)-epigallocatechin-3-gallate, Oncogene, 22:1035-1044.
Agarwal, C, Singh, R. P., Dhanalakshmi, S., Tyagi, A. K, Tecklenburg, M., Sclafani, R. A., and Agarwal, R. | | However, a growing number of reports in the pharmacology literature characterize flavonoid interactions with cellular components implicated in neurological pathologies and cancer. As the effective flavonoid concentrations employed in pharmacological studies utilizing cell cultures are often orders of magnitude higher than the serum concentrations seen in humans, some discrimination is required when interpreting these reports. | Bottom Line Health See book keywords and concepts | | Michael White, PharmD, professor of pharmacology, University of Connecticut, Storrs.
Eric J. Jacobs, PhD, epidemiologist, American Cancer Society.
Journal of the National Cancer Institute. The Journal of the American Medical Association.
Two major studies have shown that the cholesterol-lowering drugs called statins do not reduce the risk of colon cancer.
THE FIRST STUDY
One study looked at 27 trials that included nearly 87,000 people. | Fred A. Baughman, Jr., M.D. and Craig Hovey See book keywords and concepts | A DRUG IN SEARCH OF A DISEASE
The best known of the stimulants given to children, methyl-phenidate (Ritalin), was synthesized by Ciba (a pharmaceutical company that later morphed into Novartis) in 1944, with its pharmacology described in 1954. In his excellent book, The Creation of Psychopharmacology, David Healy, M.D., [2] tells us, "Later Leon Eisenberg used Ritalin in the first randomized controlled trial involving children, to test its effects on hyperactive states. | Bottom Line Health See book keywords and concepts | | William Elliott, MD, PhD, professor of preventive medicine, internal medicine and pharmacology, Rush University Medical College, Chicago.
Acupuncture Can Be as Effective as Botox
Mary Elizabeth Wakefield, licensed acupuncturist, New York City.
Shellie Goldstein, licensed acupuncturist, New York City and East Hampton, NY.
Laurie A. Casas, MD, associate professor of surgery, Feinberg School of Medicine, Northwestern University, Chicago, and spokeswoman, American Society for Aesthetic Plastic Surgery. | Bill Sardi See book keywords and concepts | The High pH Therapy for Cancer, Tests on Mice and Humans," pharmacology Biochemistry & Behavior, Supplement Q, v. 21: 1-5, 1984] Here is how it is described:
"Mass spectrographic and isotope studies have shown that potassium, rubidium, and especially cesium are most efficiently taken up by cancer cells. This uptake was enhanced by Vitamins A and C as well as salts of zinc and selenium. The quantity of cesium taken up was sufficient to raise the cell to the 8 pH range... Tests on mice fed cesium and rubidium showed marked shrinkage in the tumor masses within two weeks. |
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