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The Side Effects Bible: The Dietary Solution to Unwanted Side Effects of Common Medications

Frederic Vagnini, M.D. and Barry Fox, Ph.D.
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IBUPROFEN (eye-byoo-PROE-fen) Brand Names: Actiprofen, Advil, Advil Migraine Liqui-Gels, Apo-Ibuprofen, Bayer Select Pain Relief Formula, Children's Advil Oral Suspension, Children's motrin Oral Suspension, Dynafed IB, Genpril, Haltran, IBU, Ibuprin, Ibuprohm, Junior Strength motrin, Menadol, Midol IB, motrin, motrin IB, motrin Migraine Pain, Novo-Profen, Nu-Ibuprofen, Nuprin, Saleto-200, Saleto-400, Saleto-600, Saleto-800 About Ibuprofen In 1984, ibuprofen was approved for sale over-the-counter.

The Detox Strategy: Vibrant Health in 5 Easy Steps

Brenda Watson and Leonard Smith
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For example, if you compare the official prescribing information for prescription motrin with the over-the-counter variety (Motrin IB) label, you find that many warnings and precautions are left out. Doctors read about such side effects as edema, blurred vision, nausea, heartburn, diarrhea, gastric ulcer with bleeding and/or perforation, dizziness, nervousness, rash, and tinnitus ("ringing in the ears"). On the OTC motrin IB box, side effects are not specifically listed.

Dr. Jacob Teitelbaum, author of "Pain Free 1-2-3," discusses natural pain management, without dangerous drugs

Mike Adams, the Health Ranger
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You have $3 billion being spent on just NSAIDs like motrin and billions more on Vioxx. You have $4 billion being spent on treating the side effects of Motrin-family medications when people get put in the hospital -- because, as I mentioned, there are over 16,500 deaths a year. The recent study out of the New England Journal of Medicine had a headline like this: "Natural remedies don't work for arthritis." When you look at the data for mild arthritis, Celebrex and the natural remedies are about equally effective.

Timeless Secrets of Health & Rejuvenation: Unleash The Natural Healing Power That Lies Dormant Within You

Andreas Moritz
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According to the New England Journal of Medicine, "antiinflammatory drugs (prescription and over-the-counter medications, which include Advil, motrin, Aleve, Ordus, aspirin, and over 20 others) alone cause over 16,500 deaths and over 103,000 hospitalizations per year just in the U.S." The amount of five major painkillers sold at retail establishments rose 90 percent between 1997 and 2005, according to an Associated Press analysis of statistics from the Drug Enforcement Administration.' Even the smallest amount of aspirin triggers at least some degree of intestinal bleeding.
Originally marketed as Nurofen, it is also known under the names Act-3, Advil, Brufen, Dorival, Herron Blue, Panafen, motrin, Nuprin, Ipren, Ibumetin, Ibuprom, IbuHEXAL, Moment, Ibux, Ibufen and Ibalgin, depending on the country in which it is sold. Mostly it is used for symptoms of arthritis, primary dysmenorrhoea, fever and as an analgesic, especially where there is an inflammatory component. Popping the occasional Advil can lead to years of agonizing stomach distress.
And did you know that taking ibuprofen (Advil, motrin) in combination with aspirin actually doubles your risk of death from heart-related causes! According to a study of over 7,000 patients' medical records spanning eight years, if you take ibuprofen for any reason—say, arthritis pain relief—while engaged in aspirin therapy for heart disease, you are twice as likely to die from a heart attack or stroke because of the way these two powerful drugs interact.

The Natural Pharmacy: Complete A-Z Reference to Natural Treatments for Common Health Conditions

Alan R. Gaby, M.D., Jonathan V. Wright, M.D., Forrest Batz, Pharm.D. Rick Chester, RPh., N.D., DipLAc. George Constantine, R.Ph., Ph.D. Linnea D. Thompson, Pharm.D., N.D.
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Medical treatments Over the counter nonsteroidal anti-inflammatory drugs (NSAIDs), including aspirin (Bayer, Ecotrin, Bufferin), ibuprofen (Advil, motrin, Nuprin), and naproxen (Aleve), may be adequate to treat the pain associated with bursitis. Prescription strength NSAIDs, such as celecoxib (Celebrex), valdecoxib (Bextra), ibuprofen (Motrin), naproxen (Anaprox, Naprosyn), etodolac (Lodine), and indomethacin (Indocin), are prescribed when over the counter products are ineffective.
Vitamin E (page 609) Zinc (page 614) Medical treatments Over the counter nonsteroidal anti-inflammatory drugs (NSAIDs), including aspirin (Bayer, Ecotrin, Bufferin), ibuprofen (Advil, motrin, Nuprin), and naproxen (Aleve), as well as acetaminophen (Tylenol), are commonly used for mild pain following surgery. Prescription strength NSAIDs, including ibuprofen (Motrin), naproxen (Anaprox, Naprosyn), etodolac (Lodine), and indomethacin (Indocin), are prescribed when over the counter products are ineffective.
Medical treatments Ovet the counter nonsteroidal anti-inflammatory drugs (NSAIDs), including aspirin (Bayer, Ecotrin, Bufferin), ibuprofen (Advil, motrin, Nuprin), and naproxen (Aleve), as well as acetaminophen (Tylenol), are commonly used for mild pain. Prescription strength NSAIDs, including ibuprofen (Motrin), naproxen (Anaprox, Naprosyn), etodolac (Lodine), and indomethacin (Indocin), are prescribed when over the counter products are ineffective. Narcotic pain-relievers including codeine (Tylenol with Codeine) and hydrocodone (Vicodin, Lortab) are also used to treat moderate pain.

The Most Effective Natural Cures on Earth: The Surprising, Unbiased Truth about What Treatments Work and Why

Jonny Bowden, Ph.D., C.N.S.
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In one large randomized clinical trial, SAMe reduced the pain of osteoarthritis by 20 percent (about the same as nonsteroidal antiinflammatories like ibuprofen, Advil, or motrin, but with none of the side effects). There is reliable evidence going back to published studies in the late 1980s that SAMe possesses antiinflammatory, pain-relieving, and tissue-healing properties that may help protect the health of joints.

The Food-Mood Connection: Nutrition-based and Environmental Approaches to Mental Health and Physical Wellbeing

Gary Null and Amy McDonald
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NARLENE I used to have menstrual cramps that were so painful that I was prescribed high doses of motrin. Taking it made some of the pain go away. Since I started Gary's protocols, I have had no menstrual pain and a cyst in my breast is shrinking. I have firmer breasts, more energy, have lost weight, and now I am working on ridding myself of negative thought patterns. JEAN My husband and I began to notice our bodies were not in good condition. He was a meat and potatoes man and a very picky eater.

Dr. Jacob Teitelbaum, author of "Pain Free 1-2-3," discusses natural pain management, without dangerous drugs

Mike Adams, the Health Ranger
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In human beings, all doctors have been taught is to give motrin or Celebrex medications and Tylenol -- and narcotics if you have cancer. That's all your doctor knows about pain management, and it's pathetic because there are hundreds of effective treatments. The first thing you do is treat the underlying cause of the pain. I call it, instead of the oil light, the SHIN light. You want to treat Sleep, Hormonal problems, Infections and Nutritional support.

Your Symptoms Are Real: What to Do When Your Doctor Says Nothing Is Wrong

Benjamin H. Natelson, M.D.
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A treatment plan that's limited to a single drug for pain (like Celebrex or motrin) often is inadequate because these medicines alone are less likely to bring about substantial relief than a more comprehensive plan. If your physician does not offer you more than a prescription, ask for a referral to a specialist. A doctor's lack of familiarity with illnesses like fibromyalgia does not necessarily mean that he or she is dismissing your concerns. Here again, the issue is depth of training. Internists know a great deal about common illnesses like high blood pressure, asthma, and heart disease.

You Don't Have to be Afraid of Cancer Anymore

Bill Sardi
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Australian Ad Drug Reactions Bulletin 20: 2, 2001] Healthy adults who use anti-inflammatory drugs like aspirin, motrin or Vioxx to prevent cancer are more likely to die of a heart attack or stroke induced by these drugs than from cancer. [British Medical Journal 330:1366, 2005] Before these drugs were taken off the market temporarily by the FDA, Celebrex and Vioxx generated $5 billion in annual sales to treat rheumatoid arthritis and osteoarthritis. A daily dose of Celebrex or Vioxx costs about $2.50 a day.

Best Choices From the People's Pharmacy

Joe Graedon, M.S. and Teresa Graedon, Ph.D.
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Like everyone else, I take motrin for sore muscles. The Pedialyte has substantially reduced the soreness that I experience, and I don't need to take motrin the next day. B Vitamins B vitamins have become the superheroes of nutrients. Not only do compounds like folic acid, B6, and B12 have cardiovascular benefits, folic acid and niacin may help reduce the risk of Alzheimer's disease. One study from Taipei offers evidence that a B-complex vitamin formulation can reduce nighttime leg cramps.

Dr. Jacob Teitelbaum, author of "Pain Free 1-2-3," discusses natural pain management, without dangerous drugs

Mike Adams, the Health Ranger
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If you go ahead and just use a natural pain formula with willow bark, boswellia and cherry, it will still be much more effective than Vioxx, motrin and those families of medications, without killing over 16,000 Americans, which is the number that die unnecessarily because the media promotes those drugs each year. Remember a couple of things here: One, pain is your body's way of saying something desperately needs attention. It's like the "oil" light on your dashboard.

Overtreated: Why Too Much Medicine Is Making Us Sicker and Poorer

Shannon Brownlee
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Another physician examined the patient at the time, found nothing wrong, and sent him home with instructions to take some motrin. The man's pain got better for a few days, but then it came back. When the young emergency physician—we'll call him Dr. Brown— examined the patient, he could not put his finger on a diagnosis. Nevertheless, Brown ordered a chest CT with contrast. "I had to wake up the CT tech to do the scan," the doctor told me. "She wasn't too happy. She said, 'You want me to do a chest CT and you can't tell me why?' I didn't really know why. The guy was basically healthy.

Body Signs: From Warning Signs to False Alarms...How to Be Your Own Diagnostic Detective

Joan Liebmann-Smith, Ph. D., and Jacqueline Nardi Egan
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WARNING SIGN People with nasal polyps can be allergic to aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen (Advil, motrin) and naproxen (Aleve). Because an allergic reaction to these drugs can be life-threatening, you should avoid them unless under the close supervision of your doctor. A DRY NOSE A dry nose can be just as irritating as a running nose. And while it's probably nothing much to worry about, it may be a sign of Sjogren's syndrome, a rare but serious autoimmune disease that interferes with the production of mucus and saliva. (See Appendix I.

Bottom Line's Health Breakthroughs 2007

Bottom Line Health
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Most of us turn to acetaminophen (Tylenol) and ibuprofen (Advil, motrin) for pain relief—but there can be more effective approaches, including combining conventional and natural pain relievers. Caution: Check with your doctor before taking any new medication or supplement. ARTHRITIS There are two types of arthritis—osteoarthritis, in which cartilage between bones wears away... and rheumatoid arthritis, an autoimmune disease that inflames joints.
Popular brands: Ibuprofen is in Advil, Ex-cedrin IB, Midol Cramp, motrin and Nuprin... naproxen is in Aleve.. .fetoprq/femsinOrudisKT. Dangers: Gastrointestinal irritation as well as bleeding.. .peptic ulcers.. .kidney complications .. .reduced effectiveness of some blood pressure-lowering medications.. .rebound headaches (the pain reliever itself can cause headaches as the medication builds up in the body). What to do: Before taking an NSAID, consult a doctor if you are older than age 60 and you are taking a prescription anticoagulant, steroid, diuretic or hypertension drug daily.
These herbs work as well as Vioxx and motrin. Take 240 mg of willow bark and 1,000 mg of Boswellia daily. It can take six weeks to work. For chronic arthritis, you may need to take these for up to a year to feel the full effect. FOR RHEUMATOID ARTHRITIS •Fish oil. Studies show that fish oil (one to two tablespoons a day for at least three months) can reduce inflammation and pain. Eskimo-3, available at health-food stores, and Nordic Naturals (800-662-2544, www.nordicnaturals.com) are two reputable brands. Keep taking the fish oil after the pain is gone as a preventive measure.
Traditionally, doctors recommended that patients "go slowly" in treating rheumatoid arthritis—start by using nonsteroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen (Advil, motrin), followed by stronger drugs, as needed, through the years. But this approach doesn't always work. In the past, up to 20% of patients who had rheumatoid arthritis were disabled two years after diagnosis, and 50% were disabled 10 years after diagnosis. Newer approach: Treatment using drugs called tumor necrosis factor (TNF) blockers.

Supplement Your Prescription: What Your Doctor Doesn't Know About Nutrition

Hyla Cass, M.D.
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For example, a patient might simultaneously be put on Lipitor for cholesterol lowering, prednisone for respiratory relief, and motrin for pain. How many of the health problems that crop up in this patient are caused by drug side effects and interactions? We just don't know, since we have no long-term studies on this. What I have seen is that patients that have been on multiple drugs over long periods of time often show an overall deterioration in their health.
At that time, COX-2 inhibitor drugs like Vioxx and Celebrex, a newer class of non-steroidal anti-inflammatory drugs (NSAIDs), were replacing the older NSAIDs like Naprosyn and Aleve, motrin and Advil, and Voltaren, Athrotec, and Cataflam. The older NSAIDs were known to cause ulcers and internal bleeding, while the new "super aspirins" were supposed to reduce that risk. One day, Anna suddenly passed out and fell to the floor. She had the presence of mind, when she awoke, to call the paramedics using her Medic Alert pendant. She had begun bleeding from a gastric ulcer.

Your Symptoms Are Real: What to Do When Your Doctor Says Nothing Is Wrong

Benjamin H. Natelson, M.D.
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Next is ibuprofen (often known by brand names like motrin or Advil). Carefully done trials of this class of drugs in fibromyalgia (FM) have not shown a clear therapeutic effect, but many of my patients swear by them. The major toxicity from this class of drugs is gastric upset. A new class of NSAIDs called Cox-2 inhibitors was developed to reduce this side effect. However, a number of large studies have found that these newer drugs have a higher rate of potentially lethal side effects, such as heart attack or stroke, than the old fashioned NSAIDs.

The Detox Strategy: Vibrant Health in 5 Easy Steps

Brenda Watson and Leonard Smith
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On the OTC motrin IB box, side effects are not specifically listed. There is a mention that "ibuprofen may cause stomach bleeding," and that people should "stop use and ask a doctor if stomach pain or upset gets worse or lasts." But research has shown that most people don't want to bother their doctors with questions about nonprescription drugs. Warnings about drug interactions are also grossly incomplete. This means you take on serious risks when you take OTCs blindly; OTCs can be just as hazardous to your health as prescription medications.

The Food-Mood Connection: Nutrition-based and Environmental Approaches to Mental Health and Physical Wellbeing

Gary Null and Amy McDonald
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Aspirin has become a motrin deficiency. Cardiac arrhythmia has become a calcium channel blocker deficiency. Hypertension has become a high blood pressure pill deficiency and depression has become a Prozac deficiency. All of the thought has been removed from medicine. It becomes a no-brainer. It's like a little receipt book of computerized flow sheets and the big emphasis is on labels. Label-itis is probably the number one cause of disease or death in the United States. Once you get a label, you are locked into it.

Before You Take that Pill: Why the Drug Industry May Be Bad for Your Health

J. Douglas Bremner
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Before Vioxx and its sister medications were developed, many people suffering from joint disease managed the accompanying pain and other symptoms by taking one of several nonsteroidal anti-inflammatory drugs (NSAIDS—pronounced £«-saids) with familiar names like ibuprofen (Advil, motrin), indomethacin (Indocin), meloxicam (Mobic), diclofenac (Cataflam, Voltaren), nabumetone (Relafen), and naproxen (Aleve, Naprosyn, Naprelan, Anaprox).

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