Stephen T. Sinatra, M.D.
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 Raj Chopra, develops the "Biosolv" process, allowing for greater bioavailability of supplemental coq10 in the body.
1997
CoQ10 hits textbooks of mainstream cardiology.
1997-2004
Continued research into role of coq10 in cardiovascular health and mitochondrial diseases.
2004
Canadian government places ubiquinone on statin labels as a precaution.
2005
Blood levels of coq10 much higher when taken twice daily compared to once-a-day dosing of same amount.
2006
Introduction of Ubiquinol QH?by Kaneka.
Photograph of Raj Chopra, Stephen T. Sinatra, M.D., and Fred Crane, Ph.D. |
| CoQ10 in Ancona, Italy. Scientists and physicians report on a variety of medical conditions improved by CoQi0 administration. Blood levels of at least 2.5 ug/ml and preferably higher required for most medical purposes.
1996-1997
Gel-Tec, a division of Tishcon, Corp., under the leadership of Raj Chopra, develops the "Biosolv" process, allowing for greater bioavailability of supplemental coq10 in the body.
1997
CoQ10 hits textbooks of mainstream cardiology.
1997-2004
Continued research into role of coq10 in cardiovascular health and mitochondrial diseases. |
| Explosion of use of coq10 in health food industry.
1992
CoQ10 placed on formulary at Manchester Memorial Hospital, Manchester,
Connecticut.
1996
9th international conference on coq10 in Ancona, Italy. Scientists and physicians report on a variety of medical conditions improved by CoQi0 administration. Blood levels of at least 2.5 ug/ml and preferably higher required for most medical purposes.
1996-1997
Gel-Tec, a division of Tishcon, Corp., under the leadership of Raj Chopra, develops the "Biosolv" process, allowing for greater bioavailability of supplemental coq10 in the body. |
| Per Langsjoen in Texas reports the profound impact coq10 has in cardiomyopathy in double blind studies.
1990s
Explosion of use of coq10 in health food industry.
1992
CoQ10 placed on formulary at Manchester Memorial Hospital, Manchester,
Connecticut.
1996
9th international conference on coq10 in Ancona, Italy. Scientists and physicians report on a variety of medical conditions improved by CoQi0 administration. Blood levels of at least 2.5 ug/ml and preferably higher required for most medical purposes.
1996-1997
Gel-Tec, a division of Tishcon, Corp. |
Mike Adams, the Health Ranger
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 Without coq10, you would die in a matter of minutes.
Yet statin drugs, for example, inhibit the production of coq10 by interfering with the normal, healthy function of the liver. So when people try to lower their cholesterol with statin drugs, they often end up with a chronic deficiency of coq10. Many times, sadly, their doctors don't even tell them that they need to supplement coq10, which is one of the most important things a person needs to do when taking statin drugs. |
James F. Balch, M.D. and Mark Stengler, N.D.
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 Cholesterol [j)rugs and coq10 so
The cholesterol-lowering drugs known widely prescribed drugs today. Thes liver enzyme HMG CoA reductase, cholesterol. This same enzyme is al vital nutrient that's required for prorje journal of Clinical Pharmacology CoQl 0 levels by an average of 40 studies have also found coq10 depjl day of supplemental coq10 reversed as "statins" are among the most "statin" drugs work by inhibiting the jwhich acts to help the liver synthesize involved in the synthesis of coq10, a r heart function. |
Marshall Editions
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 It is even more helpful to take coq10 if you are on statins (cholesterol-lowering medications), since they decrease the levels of coq10 that may be contributors to liver and muscle abnormalities. Chromium, at 200-400 meg a day, increases HDL and lowers total cholesterol. Taking 400 IU of vitamin E a day helps with inhibiting cholesterol oxidation.
Herbs: Take 1,200 mg of red rice yeast a day with 60 mg of coq10. Red rich yeast has been shown to be effective in decreasing cholesterol. |
Patrick Holford
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 Foods said to be high in lipoic acid are liver and brewer's yeast. coq10 is a vital antioxidant helping protect cells from carcinogens and also helping recycle vitamin E. CoQ10's magical properties lie in its ability to improve the cell's use of oxygen. coq10 works by controlling the flow of oxygen, making the production of energy most efficient and preventing damage caused by these oxidants. coq10 is found in meat, fish, nuts, and seeds. |
Ray D. Strand
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 Multiple Sclerosis
My patients with MS have shown that at least 400 mg of grape-seed extract, 200-300 mg of coq10, and even some additional 500 to 1000 mg of vitamin C can be helpful in this disease. I warn my MS patients that it may be more than 6 months before they see any improvement.
Lupus and Crohn's Disease
These patients need about 300 mg of grape-seed extract and 200 mg of coq10 added to the basic supplements. Again, if these patients improve, it's usually after about 6 months.
Osteoarthritis
I add 1,500-2,000 mg of glucosamine sulfate and about 100-200 mg of grape-seed extract. |
| I am giving levels for the powder form in the following recommendations, You would need less CoQ1Q if you take the Q-gel or soft-gel form of CoQ10]
Specific Optimizers I Recommend Be Added to the Nutrients in Table 1 for Each of These Particular Diseases
Heart Disease
I add approximately 100 mg each of grape-seed extract and coq10 along with some additional magnesium, about 200 to 300 mg per day. |
Mike Adams, the Health Ranger
See article keywords and concepts |
 Mike: And getting back to coq10, the production of coq10 is suppressed by statin drugs, you mentioned.
Dr. Pizzorno: Yes, it is. It's suppressed by stain drugs, and also it's produced in the mitochondria, so as the mitochondria age, it's kind of like a double whammy -- they're being less functional producers of coq10, which means they're more susceptible to cell damage and they just go down quickly.
You've been reading part four of a five-part interview with Dr. Joseph Pizzorno, the founding president of Bastyr University. Dr. |
David Hoffman, FNIMH, AHG
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 Nevertheless, the body often cannot make enough for optimal function, and therefore coq10 supplements may be very helpful.
CoQI0 is highly concentrated in heart muscle cells, due to the high energy requirements of this type of cell. Congestive heart failure has been associated with low blood and tissue levels of coq10. The severity of heart failure correlates with the severity of coq10 deficiency. This coq10 deficiency may well be a primary factor in some types of heart muscle dysfunction; in others, it may be a secondary phenomenon. |
James F. Balch, M.D. and Mark Stengler, N.D.
See book keywords and concepts |
| This same enzyme is al vital nutrient that's required for prorje journal of Clinical Pharmacology CoQl 0 levels by an average of 40 studies have also found coq10 depjl day of supplemental coq10 reversed as "statins" are among the most "statin" drugs work by inhibiting the jwhich acts to help the liver synthesize involved in the synthesis of coq10, a r heart function. A 1993 study in the that the use of statin drugs reduced pjercent after three months of use. Other etion effects. In one study, 100 mg per this effect. |
Mike Adams, the Health Ranger
See article keywords and concepts |
| Mike: And getting back to coq10, the production of coq10 is suppressed by statin drugs, you mentioned.
Dr. Pizzorno: Yes, it is. It's suppressed by stain drugs, and also it's produced in the mitochondria, so as the mitochondria age, it's kind of like a double whammy -- they're being less functional producers of coq10, which means they're more susceptible to cell damage and they just go down quickly.
You've been reading part four of a five-part interview with Dr. Joseph Pizzorno, the founding president of Bastyr University. Dr. |
Patrick Holford
See book keywords and concepts |
| CoQ10 is a vital antioxidant helping protect cells from carcinogens and also helping recycle vitamin E. CoQ10's magical properties lie in its ability to improve the cell's use of oxygen. coq10 works by controlling the flow of oxygen, making the production of energy most efficient and preventing damage caused by these oxidants. coq10 is found in meat, fish, nuts, and seeds. |
Stephen T. Sinatra, M.D.
See book keywords and concepts |
| Continued research into role of coq10 in cardiovascular health and mitochondrial diseases.
2004
Canadian government places ubiquinone on statin labels as a precaution.
2005
Blood levels of coq10 much higher when taken twice daily compared to once-a-day dosing of same amount.
2006
Introduction of Ubiquinol QH?by Kaneka.
Photograph of Raj Chopra, Stephen T. Sinatra, M.D., and Fred Crane, Ph.D., taken in February 2006. which indeed turned out to be a missing link. Dr. Folkers determined its chemical structure to be 2,3-dimethyoxy-5 methyl-6 decaprenyl-1, 4 benzoquinone.
In 1957, Dr. D. E. |
Mike Adams, the Health Ranger
See article keywords and concepts |
| Yet statin drugs, for example, inhibit the production of coq10 by interfering with the normal, healthy function of the liver. So when people try to lower their cholesterol with statin drugs, they often end up with a chronic deficiency of coq10. Many times, sadly, their doctors don't even tell them that they need to supplement coq10, which is one of the most important things a person needs to do when taking statin drugs. |
Marshall Editions
See book keywords and concepts |
| Take 60-100 mg of coq10 a day for at least eight weeks. Some studies show that folic acid in a 0.1% solution used as a mouth rinse has reduced gum inflammation and bleeding. Rinse the mouth with 5 ml of solution, available from health food stores, twice a day for one to five minutes for 30-60 days. Zinc stabilizes the gum membrane, increases antioxidant activity, promotes collagen synthesis, inhibits plaque growth, and performs numerous immune activities. Take 15-30 mg of the picolinate form a day. |
Mike Adams, the Health Ranger
See article keywords and concepts |
 I've put my patients with Parkinson's on greens and coq10 and other supplements. Soon they're able to feed themselves. Did we get rid of the Parkinson's? No. But they're able to feed themselves. That counts, too.
It's not been studied, so I don't know how you double blind study changing nutritional habits. And it's a flaw of models. You know, conventional models study a single entity to death and find out everything about it. With a natural model, nobody's ever going to say, "Okay, take this vitamin E, take this coq10, but don't eat them." It's a multi-therapeutic model. |
Jonny Bowden, Ph.D., C.N.S.
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 So What Is coq10, Anyway?
CoQ 10 isn't a vitamin; it actually belongs to a family called ubiquinones, and it's found in most tissues in the body. It's essential for the manufacture of the body's energy molecule, ATP (adenosine triphosphate). Virtually every one of the studies investigating the effect of CoQ 10 on heart muscle function have reported significant and positive results. "If there is just one thing you do to help maintain your heart's health," says Sinatra, "make sure you're taking CoQ 10 daily. |
Mike Adams, the Health Ranger
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 Jonathan Wright, the "CoQ10" raid on Highland Laboratories, the El Cajon pet food store raid (the owner committed the "crime" of saying that vitamins were good for pets) and multiple, armed "terror-style" raids against the Life Extension Foundation, among many others. The FDA has confiscated "dangerous" products like flaxseed oil, herbal tea, vitamin C and coq10, all in its quest to save the public from the terrible dangers of nutritional medicine. |
Sheldon Saul Hendler
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 CoQ10 is said by these researchers to enhance the pumping capacity of the heart and to eliminate the often major side effects associated with conventional heart-failure drugs. Heart-failure patients were said to have a relative deficiency of coq10 in their hearts and to be responsive to daily oral supplements of coq10, which, it is reported, increases the production of energy in heart-muscle cells. Some 91 percent of the patients studied showed improvement within thirty days of beginning coq10 supplementation. Certainly more investigation of this intriguing vitamin-like nutrient is warranted. |
Mike Adams, the Health Ranger
See article keywords and concepts |
 To help educate customers about the healing power of coq10, he offered to send reprints of magazine and newspaper articles describing some of the scientific findings about the nutrient.
This public education effort, of course, would not be tolerated by the FDA Gestapo. So the FDA organized an armed raid comprised of nine FDA agents, 11 U.S. Marshals and eight Oregon state police. With guns drawn, they kicked in the doors to Ken Scott's business and conducted one of the most terror-driven "vitamin" raids in U.S. history. |
David Hoffman, FNIMH, AHG
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| Each pair of electrons processed by the chain must first interact with coq10, and no other substance will substitute for coq10. Other familiar substances involved in this electron transport chain include vitamin C, riboflavin (vitamin B2), niacinamide (vitamin B3), and vitamin E.
CoQ10 is naturally present in small amounts in a wide variety of foods, but is particularly high in organ meats, such as heart, liver, and kidney, and in beef, soy oil, sardines, mackerel, and peanuts. |
Mike Adams, the Health Ranger
See article keywords and concepts |
| Ken Scott was ultimately forced to cut a deal with prosecutors, and eventually served five years on probation for his "crime" of telling the truth about coq10.
The message from the FDA to other vitamin companies couldn't be more clear: Don't you dare tell your customers the truth about vitamins, or we'll shut you down and prosecute you!
1990: The Century Clinic "chelation" raids
In Reno, Nev., 1990, the Century Clinic was raided by the FDA and Postal Service inspectors. |
David Hoffman, FNIMH, AHG
See book keywords and concepts |
| Each pair of electrons processed by the chain must first interact with coq10, and no other substance will substitute for coq10. Other familiar substances involved in this electron transport chain include vitamin C, riboflavin (vitamin B2), niacinamide (vitamin B3), and vitamin E.
CoQ10 is naturally present in small amounts in a wide variety of foods, but is particularly high in organ meats, such as heart, liver, and kidney, and in beef, soy oil, sardines, mackerel, and peanuts. |
Mike Adams, the Health Ranger
See article keywords and concepts |
 Statin drugs, of course, interfere with the production of coq10 at the cellular level, throughout the body. It interferes with the mitochondria in the cells, and as a result, people suddenly have coq10 deficiencies, and they can't manufacture cholesterol the way they used to be able to as well. Suddenly, they are lacking in sex hormones, because sex hormones are manufactured from cholesterol, and now that they are taking statin drugs they can't make cholesterol. So now they have no sex drive left.
Of course, they think this is just an aging problem. |
Mike Adams, the Health Ranger
See article keywords and concepts |
 Cholesterol-lowering statin drugs, for example, greatly interfere with Coenzyme Q10 production (a nutrient essential for cellular energy), but instead of being told to take supplemental coq10, many patients suffering from fatigue and exhaustion on statin drugs are simply diagnosed with another disease and given yet another prescription drug to take.
Antidepressant drugs, as another example, interfere with the metabolism of carbohydrates. Most people taking antidepressants are deficient in the B vitamins (especially folic acid). |
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