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Comfortably Numb: How Psychiatry Is Medicating a Nation Charles Barber See book keywords and concepts

Which was nothing compared to the stock options held by the CEO of bristol-myers squibb, which amounted to $227 million. And it's not just the CEOs: in 2000, the average unexercised stock options of the top executives at Merck were $73 million; at bristol-myers squibb, $65 million; at Pfizer, $54 million; at Eli Lilly, $33 million.

America Fooled: The Truth About Antidepressants, Antipsychotics and How We've Been Deceived Dr. Timothy Scott See book keywords and concepts

Wagner has received research support from Abbott, bristol-myers squibb, Eli Lilly, Forest Laboratories, GlaxoSmithKline, Organon, Pfizer, and Wyeth-Ayerst; has served as a National Institute of Mental Health consultant to Abbott, bristol-myers squibb, Cyberonics, Eli Lilly, Forest Laboratories, GlaxoSmithKline, Novartis, Otsuka, Janssen, Pfizer, and UCB Pharma; and has participated in speaker's bureaus for Abbott, Eli Lilly, GlaxoSmithKline, Forest Laboratories, Pfizer, and Novartis.2 The study's principal statistician was Dr. Ruoyong Yang. Both he and another of the study's authors, Dr.

Overtreated: Why Too Much Medicine Is Making Us Sicker and Poorer Shannon Brownlee See book keywords and concepts

Kathleen Slattery-Moschkau is a former rep who carried the bag for nine years for bristol-myers squibb and Johnson & Johnson before quitting to write and direct Side Effects, an independent film about a fictional drug rep. She recalls that the pressure on reps to hit their quotas was intense. "If Pfizer was having a dinner at a really nice restaurant, you had to come up with [Green Bay] Packers tickets—and a bus to the game," she says. As reps upped the gift-giving ante, doctors began feeling entitled to increasingly luxurious favors.

PDR for Herbal Medicines, Fourth Edition Thomson Healthcare, Inc. See book keywords and concepts

Product Information: Reyataz (atazanavir). bristol-myers squibb Company, Princeton, NJ (PI issued 6/2003) reviewed 7/2003. Product Information: Soriatane (acitretin). Roche Laboratores, Inc, Nutley, NJ; 4/2003. Product Information: Zomig (zolmitriptan tablets). Zeneca Pharmaceuticals, Wilmington, DE; 1999. Prost N. Tichadou L, Rodor F, et al: Interaction millcpcrtuis-venlafaxine (Article in French). Presse Med 29:1285-1286. 2000. Quandt J, Schmidt U, Schenk N. Ambulante Behandlung leichter und mittelschwerer depressiver Verstimmungen. Allgemeinarzt 2:97-102. 1993. Raffa RB.

Bottom Line's Health Breakthroughs 2007 Bottom Line Health See book keywords and concepts

Funding for the trial was provided by the makers and distributors of Plavix, Sanofi-Aventis and bristol-myers squibb. . , You can learn more about clopidogrel by — visiting the US National Library of Medicine's MedlinePlus Web site at www.medlineplus. gov. Click on "Drugs & Supplements." Should You Be Taking Aspirin? Anew study suggests that some people who are age 70 and older may be better off not using aspirin to protect themselves against cardiovascular disease. Theoretical calculations show that aspirin therapy could cause 57% more life-threatening hemorrhages in this age group.

America Fooled: The Truth About Antidepressants, Antipsychotics and How We've Been Deceived Dr. Timothy Scott See book keywords and concepts

Eleven of the 12 principal authors had financial ties with bristol-myers squibb as did most of the study's 17 secondary authors. Two were employees of the company. Nearly all the authors received income from the drug manufacturer in one or more ways—as consultants, advisory board members, or as honorarium or grant recipients. The study itself was paid for by bristol-myers squibb. That is not the end of the story.

Wagner has received research support from Abbott, bristol-myers squibb, Eli Lilly, Forest Laboratories, GlaxoSmithKline, Organon, Pfizer, and Wyeth-Ayerst; has served as a National Institute of Mental Health consultant to Abbott, bristol-myers squibb, Cyberonics, Eli Lilly, Forest Laboratories, GlaxoSmithKline, Novartis, Otsuka, Janssen, Pfizer, and UCB Pharma; and has participated in speaker's bureaus for Abbott, Eli Lilly, GlaxoSmithKline, Forest Laboratories, Pfizer, and Novartis.2 The study's principal statistician was Dr. Ruoyong Yang. Both he and another of the study's authors, Dr.

Comfortably Numb: How Psychiatry Is Medicating a Nation Charles Barber See book keywords and concepts

There is a new magazine, bp (underwritten by Pfizer and bristol-myers squibb), offering hope for people suffering from bipolar disorder. Monk, a show about a detective with obsessive-compulsive disorder who uses his illness adaptively to perceive things that normal people can't, is one of the most popular programs on cable television and has received a gaggle of Screen Actors Guild, Emmy, and Edgar awards.

And it's not just the CEOs: in 2000, the average unexercised stock options of the top executives at Merck were $73 million; at bristol-myers squibb, $65 million; at Pfizer, $54 million; at Eli Lilly, $33 million.5 Even after the woes that Big Pharma experienced between 2004 and 2007—the withdrawal of Vioxx from the market, the loss of half of the injectable flu vaccines because of quality control problems, and a growing public awareness of profiteering and an all-too-cozy relationship with the Bush administration—no one should worry unduly about the industry's fortunes.

Our Daily Meds: How the Pharmaceutical Companies Transformed Themselves into Slick Marketing Machines and Hooked the Nation on Prescription Drugs Melody Petersen See book keywords and concepts

After one of Armstrong's Tour de France victories, the company paid for advertisements proclaiming, "This miracle is brought to you by bristol-myers squibb." However, the truth behind the discovery of the medicines that saved Armstrong got lost in the frenzy of international publicity as he appeared for Bristol-Myers on television shows like ABC's Good Morning America and Live with Regis and Kathie Lee.

NOTES BIBLIOGRAPHY ACKNOWLEDGMENTS INDEX NOTES Abbreviations BMJ British Medical Journal JAMA The Journal of the American Medical Association NEJM The New England journal of Medicine Introduction 4 Vaniqa: bristol-myers squibb began selling Vaniqa as a facial hair removal cream in 2000 through an aggressive marketing campaign that included ads on television and in magazines like Cosmopolitan. Controversy erupted when the public realized a drug being used to minimize the mustaches of American women was not available to people dying of sleeping sickness in Africa.

The Whistleblower: Confessions of a Healthcare Hitman Peter Rost See book keywords and concepts

In 2004 the Securities and Exchange Commission (SEC) ordered bristol-myers squibb to pay $ 150 million to settle charges that it inflated its revenue by $1.5 billion in 2000 and 2001. The penalty was one of the largest levied against a company accused of accounting fraud.26 The settlement concluded a two-year SEC investigation of the company, but the bad news for bristol-myers squibb didn't stop there. A separate criminal investigation by the U.S.

Our Daily Meds: How the Pharmaceutical Companies Transformed Themselves into Slick Marketing Machines and Hooked the Nation on Prescription Drugs Melody Petersen See book keywords and concepts

In 2001 Peter Dolan, a young executive who had made his early mark promoting Jell-O for General Foods, became the chief executive of bristol-myers squibb. The drug company Novartis hired the Pepsi marketer Thomas Ebeling and by 2000 had given him responsibility for running its global pharmaceutical business. When Randall Tobias took over as the head of Eli Lilly in 1993, he had spent most of his career as an executive for the phone company AT&T.

The Whistleblower: Confessions of a Healthcare Hitman Peter Rost See book keywords and concepts

The settlement concluded a two-year SEC investigation of the company, but the bad news for bristol-myers squibb didn't stop there. A separate criminal investigation by the U.S. Attorney General's office in New Jersey resulted in the indictment of two executives: The former senior vice president and chief financial officer, and the former executive vice president and president of the Bristol-Myers Squibb's world-wide medicines group. Both were charged with securities fraud and conspiracy to commit securities fraud, for planning and executing channel stuffing at the company.

The Food-Mood Connection: Nutrition-based and Environmental Approaches to Mental Health and Physical Wellbeing Gary Null and Amy McDonald See book keywords and concepts

In one recent case, a Louisiana judge ordered bristol-myers squibb, the company that manufactures and distributes Prolixin, to pay $2 million to a fifty-two-year-old woman who developed severe and disabling tardive dyskinesia after taking the drug for five years. Among her symptoms were muscle spasms and abnormal movements of the face, neck, shoulders, and extremities, as well as impaired speech and breathing. More than thirty years ago, according to Dr.

Our Daily Meds: How the Pharmaceutical Companies Transformed Themselves into Slick Marketing Machines and Hooked the Nation on Prescription Drugs Melody Petersen See book keywords and concepts

On the afternoon of September 28, 2000, executives at bristol-myers squibb invited scores of Wall Street analysts and investors to a ballroom in a grand hotel on the East Side of Manhattan. On a stage with a multicolored backdrop, the company's top two executives, Charles Heimbold and Peter Dolan, stepped up to announce that Bristol-Myers was embarking on what they called the MegaDouble plan. The company would now focus its efforts, the executives said, on marketing only those drugs with the potential to bring in several billion dollars a year. They called these products megablockbusters.

For example, Bristol-Myers Squibb's bestselling cancer drug Taxol was discovered by scientists funded through government grants. The federal government then paid to manufacture the drug and to test it in patients, before granting a license to Bristol-Myers to sell it. In fact, of the nation's twenty-one most important drugs introduced between 1965 and 1992, fifteen were developed using knowledge from federal-funded research, according to a report in 2000 by the Joint Economic Committee of Congress, then headed by Republican senator Connie Mack.

These are the gifts and payments he has received from these companies in the last two years: January 17, dinner and drinks at Daniel, compliments of Forest Labs, value three hundred dollars; January 23, fee for speaking about a new asthma drug, compliments of GlaxoSmithKline, two thousand dollars; February 12 to 15, educational conference in Aspen, Colorado, sponsored by Pfizer, Merck, and bristol-myers squibb, value of the corporate subsidies to Dr. Jones, twenty-five hundred dollars; and so on.

Big Pharma: Exposing the Global Healthcare Agenda Jacky Law See book keywords and concepts

But others, such as bristol-myers squibb, which markets one of the least potent statins, Pravachol, insist patients glean little incremental benefit by reducing their LDL levels too much. Doctors, and their patients, are naturally interested if lower really is better. But pharma companies are usually reluctant to pit their drugs against competitors in head-to-head studies, unless they have reason to believe the results would favour their product.

Handbook of Medicinal Plants Amarjit S. Basra See book keywords and concepts

NOTES 1. bristol-myers squibb Company, . 2. Guan, W.B., Huang, W.J., Zhou, Y.C., and Gong, J. Z., 1982, Effect of artemisinin and its derivatives on Plasmodium falciparum in vitro, Acta Pharma-cologica Sinica, 3(2): 139-141. 3. Klayman, D.L., 1985. Qinghaosu (artemisinin): An antimalarial drug from China, Science, 228(4703): 1049-1055. 4. Li, Y, Yu, PL., Chen, Y.X., Li, L.Q., Gai, Y.Z., Wang, D.S., and Zheng, Y.P., 1981, Studies on analogues of artemisinin. Acta Pharmaceutica Sinica, 16(6): 429-439. 5. Brossi, A., Venugopalan, B., Gerpe, L.D., Yeh, H.J.C.

America Fooled: The Truth About Antidepressants, Antipsychotics and How We've Been Deceived Dr. Timothy Scott See book keywords and concepts

The bristol-myers squibb antidepressant Serzone (nefazodone) was first made available to both U.S. and Canadian citizens in 1994. Numerous drugs that have been approved for use by the FDA were later found to cause liver damage. (All drugs are, in one sense, poisons. It is the liver's job to filter out and break down any "poison" such as alcohol and illegal or legal drugs. Hence, regular intake of any of these has the potential to harm the liver and to a lesser extent, the kidneys, the body's other filter.) But the warnings about Serzone were particularly clear.

More Natural Cures Revealed: Previously Censored Brand Name Products That Cure Disease Kevin Trudeau See book keywords and concepts

You may recognize some of the following names: Aventis, King Pharmaceuticals, bristol-myers squibb, Bayer, GlaxoSmithKline, Novartis, Pfizer, Roche, Abbott Laboratories, Genentech, Pharmacia, Astrazeneca, Natural-Source Vitamin E Association, and several others. These are the same companies that produce drugs that kill hundreds of thousands of people each year. Only these companies have the type of money that could fund such a study, representing their own interests, and not the public's. The next question is for what purpose was this study funded?

The Whistleblower: Confessions of a Healthcare Hitman Peter Rost See book keywords and concepts

ACSH: Pfizer, bristol-myers squibb, Merck, Abbott Laboratories, Eli Lilly, American Cyanamid, Ciba-Geigy, Hoffman-La Roche, Johnson & Johnson, Rhone-Poulenc, Sandoz, Searle, Syntex, Warner-Lambert, Upjohn, and the Pharmaceutical Manufacturers Association.4 In a way I felt honored to be officially nominated 'Whiny Whistleblower of the Year' by a front organization paid by Pfizer and Big Pharma, since I apparently competed against two real consumer heroes; Dr. David Graham, FDA, and Dr. Eric Topol, the Cleveland Clinic.

The China Study: The Most Comprehensive Study of Nutrition Ever Conducted and the Startling Implications for Diet, Weight Loss and Long-term Health T. Colin Campbell, Ph.D. and Thomas M. Campbell II See book keywords and concepts

The Dannon Institute, Egg Nutrition Board, National Cattlemen's Beef Association, National Dairy Council, Nestle Clinical Nutrition, Wyeth-Ayerst Laboratories, bristol-myers squibb Company, Baxter Healthcare Corporation and others have all joined forces to produce a Nutrition in Medicine program and the Medical Nutrition Curriculum Initiative.9'10 Do you think that this all-star team of animal foods and drug industries representatives is going to objectively judge and promote optimal nutrition, which science has shown to be a whole foods, plant-based diet that minimizes the need for drugs?

Big Pharma: Exposing the Global Healthcare Agenda Jacky Law See book keywords and concepts

Pharma company, bristol-myers squibb (BMS), was also thrown into some disarray because it had paid $2 billion for a 20% stake in ImClone plus the US marketing rights to Erbitux, the jewel in its crown. Even with all the due diligence a company the size of BMS can afford, still pharmaceuticals are a seriously risky business. All that changed, of course, when the concerns to do with the study design had been ironed out and Erbitux did get its first licence.

America Fooled: The Truth About Antidepressants, Antipsychotics and How We've Been Deceived Dr. Timothy Scott See book keywords and concepts

But when Martin Keller, a psychiatrist at Brown University, and his colleagues published a study of an antidepressant manufactured by bristol-myers squibb, the conflict-of-interest disclosures were so extensive that Dr. Angell concluded she could not print the entire list in the paper version of the journal. Instead she put the information on the New England Journal of Medicine's website and then wrote an editorial with the stinging title "Is Academic Medicine for Sale?

Big Pharma: Exposing the Global Healthcare Agenda Jacky Law See book keywords and concepts

The drug, Bristol-Myers Squibb's cholestyramine, had to be sprinkled onto food making it taste ghastly, and two-thirds of those taking it reported side effects of constipation, gas, heartburn and bloating. After seven years of this ordeal, 30 of the 1,900 people taking the drug had suffered a fatal heart attack compared to 38 in the control group. This does correlate with a 25% drop in risk because the difference, eight, is roughly 25% of 38. But it took seven years and an awful lot of effort and expense to 'save' eight lives.

Generation Rx: How Prescription Drugs are Altering American Lives, Minds, and Bodies Greg Critser See book keywords and concepts

Consider Raymond Sacchetti, the head of "compliance and persistency" at bristol-myers squibb. Sacchetti had made a study of patient compliance and what he called "adherence marketing," and he could prove that DTC resulted in better persistence. "If you do a hundred sixty days of DTC ads," he told the audience, "well, you get a thirty-five percent rate of compliance after twelve months. But if you do two hundred fifty days of DTC ads, you get sixty-five percent!

America Fooled: The Truth About Antidepressants, Antipsychotics and How We've Been Deceived Dr. Timothy Scott See book keywords and concepts

The study itself was paid for by bristol-myers squibb. That is not the end of the story. By 2002 the New England Journal of Medicine found that obtaining reviewers without financial ties to drug companies was so difficult they felt it necessary to change their conflict-of-interest policy. Today it no longer states that there cannot be any financial interest in the drugs being evaluated. Today the policy states that there cannot be any "significant" interest, meaning amounts exceeding $10,000 per year.

Generation Rx: How Prescription Drugs are Altering American Lives, Minds, and Bodies Greg Critser See book keywords and concepts

Even its manufacturer, bristol-myers squibb, claimed that Serzone was mainly for people for whom all of the other antidepressants did not work. Yet its hepatotoxicity was clear, and reports during the years immediately after its release, both at the FDA and at Squibb, indicated that people were suffering from it. Worse, Serzone was a potent liver enzyme inhibitor, which meant that it prevented the liver from processing other drugs properly, leading to further injury from everything from statins to other central nervous system drugs.

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