J. Douglas Bremner
See book keywords and concepts |  A drug called imipramine (Tofranil), developed in the 1940s for the treatment of tuberculosis, helped a number of the depressed patients on the tuberculosis wards in terms of their depression (if not their tuberculosis). This led psychiatrists in France, and later the U.S., to try this drug on patients hospitalized for depression. This was the birth of the tricyclic medications.
Tricyclics, which include doxepin (Sinequan), amoxapine (Asendin), and amitriptyline (Elavil), increase norepinephrine and serotonin levels in the synapses (the spaces between the nerve cells in the brain). |
Jay Joseph
See book keywords and concepts |  In his 1938 family study, Kallmann found an "enormous increase" in mortality from tuberculosis among the children of schizophrenia patients.4 In addition, he found that almost 22% of these patients had themselves died of tuberculosis. This led him to conclude that schizophrenia and tuberculosis were genetically related to each other, and that "a very particular significance must be assigned to tuberculosis in the entire heredity-circle of schizophrenia. | | Kallmann's correlation, however, was spurious because he failed to recognize that the high rate of tuberculosis among schizophrenia patients and their relatives was the result of environmental conditions common to both schizophrenia and tuberculosis patients. Had Kallmann created a "schizophrenia spectrum" in 1938, tuberculosis would have likely been a part of it ?and with greater justification than any of the non-Bl Danish-American SSDs. |
Ann M. Coulston and Carol J. Boushey
See book keywords and concepts |  In the case of tuberculosis, macrophages are activated via recognition of M. tuberculosis lipopeptides by a TLR2/1 dimer. This interaction triggers antibacterial mechanisms of the macrophage, including the production of the antibacterial peptide cathelicidin, which can kill susceptible pathogens [25]. Cathelicidin transcription is enhanced by l,25(OH)2D acting via the VDR to increase gene transcription. |
Gerald E. Markle and Frances B. McCrea
See book keywords and concepts |  Between 1900 and 1971, reductions in mortality from tuberculosis accounted for 16.5% of the total decrease in mortality. Yet most of this benefit occurred prior to the availability of antibiotics. According to calculations by the McKinleys, only 8.4% of the total decline in tuberculosis mortality can be attributed to modern treatment, and such treatment was responsible for only 1.4% of the total decline in the standardized death rate. | | Of airborne diseases, the great success story and exemplar of orthodoxy would seem to be tuberculosis. In England and Wales, the death rate from that dreaded disease declined from 2,901 per million in the mid-nineteenth century to only 13 per million in 1971, accounting for 17.5% of the total reduction in standardized death rates. The story is similar for the United States, where from 1900 to 1970, fewer fatalities from tuberculosis accounted for 16.5% of the decline in standard death rate. Yet the story is not so easily interpreted. |
Roberta Bivins
See book keywords and concepts |  Srinivasamurti then addressed the specific cases of cholera and tuberculosis, diseases closely identified with germ theory, the new pubhc health—and with medically justified compulsion in both Europe and European colonies (compulsion which met with strong pubHc resistance and condemnation in both places):
[E]ven in the case of diseases like cholera and tuberculosis, which are definitely stated to be due to specific bacteria, the chain of evidence is by no means so strong as it is generally stated to be. |
Gerald E. Markle and Frances B. McCrea
See book keywords and concepts | | Drug therapy was not introduced until the midst of World War II and not commonly used until 1948; BCG vaccine, produced from weakened bovine tuberculosis bacilli, followed a few years later. It is true that in England and Wales death from tuberculosis decreased 51% from 1948 to 1971. Yet this reduction is less significant than it might appear. Closer analysis shows that the introduction of streptomycin barely changed the slope of decline, and that, moreover, chemotherapy accounted for only 3.2% of the entire reduction of deaths since 1848 from that once dreaded disease. |
Hyla Cass
See book keywords and concepts |  ISONIAZID
This drug is used to treat tuberculosis, or to prevent it in people who are exposed to the disease. Isoniazid is sold under the brand names Lani-azid Oral and Nydrazid Injection.
Action: It's used in combination with other drugs to kill the bacteria called mycobacteria that cause tuberculosis.
Side effects: Rarely, severe liver problems that lead to hepatitis; more commonly, stomach upset, dizziness, heartburn, or nausea.
Nutrients depleted: Calcium, folic acid, vitamins B3 and B6, and vitamin D.
Needed supplements:
?Calcium: 1,000-1,200 mg daily.
?Folic acid: 400-800 meg
? |
Dr. Sharon Moalem
See book keywords and concepts |  New research suggests that, sure enough, carrying a copy of the gene that causes cystic fibrosis seems to offer some protection from tuberculosis. tuberculosis, which has also been called consumption because of the way it seems to consume its victims from the inside out, caused 20 percent of all the deaths in Europe between 1600 and 1900, making it a very deadly disease. And making anything that helped to protect people from it look pretty attractive while lounging in the gene pool. |
Roberta Bivins
See book keywords and concepts | | Srinivasamurti then addressed the specific cases of cholera and tuberculosis, diseases closely identified with germ theory, the new pubhc health—and with medically justified compulsion in both Europe and European colonies (compulsion which met with strong pubHc resistance and condemnation in both places):
[E]ven in the case of diseases like cholera and tuberculosis, which are definitely stated to be due to specific bacteria, the chain of evidence is by no means so strong as it is generally stated to be. |
Dr. Sharon Moalem
See book keywords and concepts | | New research suggests that, sure enough, carrying a copy of the gene that causes cystic fibrosis seems to offer some protection from tuberculosis. tuberculosis, which has also been called consumption because of the way it seems to consume its victims from the inside out, caused 20 percent of all the deaths in Europe between 1600 and 1900, making it a very deadly disease. And making anything that helped to protect people from it look pretty attractive while lounging in the gene pool. |
Jay Joseph
See book keywords and concepts | | Kallmann's correlation, however, was spurious because he failed to recognize that the high rate of tuberculosis among schizophrenia patients and their relatives was the result of environmental conditions common to both schizophrenia and tuberculosis patients. Had Kallmann created a "schizophrenia spectrum" in 1938, tuberculosis would have likely been a part of it ?and with greater justification than any of the non-Bl Danish-American SSDs. |
Gerald E. Markle and Frances B. McCrea
See book keywords and concepts | | It is true that in England and Wales death from tuberculosis decreased 51% from 1948 to 1971. Yet this reduction is less significant than it might appear. Closer analysis shows that the introduction of streptomycin barely changed the slope of decline, and that, moreover, chemotherapy accounted for only 3.2% of the entire reduction of deaths since 1848 from that once dreaded disease.14
The story repeats itself in the United States. Between 1900 and 1971, reductions in mortality from tuberculosis accounted for 16.5% of the total decrease in mortality. |
Joan Liebmann-Smith, Ph. D., and Jacqueline Nardi Egan
See book keywords and concepts |  Night sweats are also a classic clue to both tuberculosis (TB) and malaria. Cough and fever are other frequent signs of TB, while malaria is often accompanied by nausea, headaches, and chills. Interestingly, sweating often accompanies the chills that are also common with these infections.
Night sweats can be an early warning sign of some forms of cancer,
SIGNIFICANT FACT
Male sweat can be a turn-on to women, according to a recent study at the University of California, Berkeley. | | Orange stools are also a common reaction to the drug rifampin, which is used to treat certain bacterial infections, especially tuberculosis, below.)
(See Golden Pee, SIGN OF THE TIMES
RED OR MAROON STOOLS
We all see red occasionally. However, seeing red in your stools may set off a red alert. Fortunately, sometimes it's just a false alarm. While what you're seeing may indeed be blood and signal a serious disorder, it can also be a harmless sign that you've eaten or drunk large amounts of something red.
It's not just leeches and maggots that have recently caught on for medical treatments. |
Brigitte Mars, A.H.G.
See book keywords and concepts |  Asparagus root is used to treat acid indigestion, AIDS, cancer and the side effects of chemotherapy, chronic fever, cystitis, diarrhea, dry cough, dry skin, dysentery, Epstein-Barr virus, erectile dysfunction, female organ weakness, frigidity, gout, herpes, infertility, jaundice, kidney stones, low libido, low sperm count, menopause symptoms, poor memory, post-hysterectomy dryness, rheumatism, sciatica, tuberculosis, ulcers, and vaginal dryness. It can be used to encourage healing during convalescence. | | Today, comfrey tea is used to treat acne, arthritis, asthma, bronchitis, burns, cough, diarrhea, dysentery, eczema, fractures, gallstones, heartburn, hemorrhage, laryngitis, pneumonia, pleurisy, tonsillitis, tuberculosis, ulcers, underweight conditions, and whooping cough.
Allantoin, a biogenic stimulator that is one of comfrey's important ingredients, is used in lotions to treat dry, rough, or wrinkled skin. | | It is used to treat asthma, bronchitis, colds, cough, diarrhea, emphysema, flu, gastritis, hoarseness, laryngitis, shortness of breath, tuberculosis, wheezing, and whooping cough. Coltsfoot is a common ingredient in cough syrups; the flowers can be soaked in honey to make a cough-relieving honey.
Topically, the leaf can be used as a poultice to treat insect bites, puffy eyes, sore feet, and wounds. As a facial toner or steam, the leaf has antiseptic and oil-reducing properties and is used to curb blemishes. The flower can be prepared as a soothing eyewash or as a hair rinse to treat dandruff. | | Chickweed is used to treat appendicitis, asthma, bladder irritation, bronchitis, constipation, cough, cysts, hoarseness, obesity, pleurisy, rheumatism, thyroid irregularities, tuberculosis, and ulcers.
Topically, chickweed can be used as a bath herb to soothe dry skin and chicken pox or as compress, poultice, or salve to treat boils, burns, diaper rash, eczema, hemorrhoids, itchy skin, nettle sting, psoriasis, rheumatism, and varicose veins. The fresh juice can be applied to eyes to treat cases of infection such as conjunctivitis.
Edible Uses
Chickweed is edible raw or cooked. |
Joan Liebmann-Smith, Ph. D., and Jacqueline Nardi Egan
See book keywords and concepts | | The hump can also be a telltale sign or tuberculosis, a spinal tumor or injury, or degenerative arthritis. (See Stiff Joints, below.)
The spine is a series of bones running down your back. You sit on one end of it and your head sits on the other.
—Anonymous
WARNING SIGN
An osteoporosis-related hip fracture is a warning sign of increased risk of death. Nearly 1 out of 4 people older than 50 who break a hip die in the year following the fracture. Many of those who survive will require long-term care because they're left with significant trouble walking. |
David W. Grotto, RD, LDN
See book keywords and concepts |  Also used as a cough expectorant, and as treatment for food poisoning, scurvy, tuberculosis, and colic. In the southern United States, horseradish rubbed on the forehead was a popular method of getting rid of headaches.
WASABI: Wasabi's antibacterial properties were first documented in a tenth-century Japanese medical encyclopedia. It was believed to be an antidote to food poisoning, making it a natural accompaniment to raw fish.
Throw Me a Lifesaver!
HEART HEALTH: A rat study found that the isothiocyanates in Wasabi inhibit platelet aggregation and deaggregation. |
Joan Liebmann-Smith, Ph. D., and Jacqueline Nardi Egan
See book keywords and concepts | | Clubbed fingers can also signal other cancers and such lung diseases as cystic fibrosis and tuberculosis. In addition, they can be markers for Crohn's disease and ulcerative colitis (see Chapter 8), and for heart disease, hyperthyroidism (see Appendix I), and liver disease.
CURLED FINGERS
CLUBBED FINGERS
SIGN OF THE TIMES
Dupuytren's disease is thought to have originated with the Vikings, who conquered the British Isles and much of northern Europe. Through intermarriage, they spread the disease throughout these areas.
Have you ever noticed someone whose fingers are always bent like a claw? |
David W. Grotto, RD, LDN
See book keywords and concepts | | Home Remedies
In India, green cardamom is used to treat a range of maladies such as periodontal infections, sore throats, lung congestion, tuberculosis, inflammation, and digestive disorders. It is also reportedly used as an antidote for both snake and scorpion venom.
The Amomum species is used extensively in traditional Indian medicine. Traditional Chinese medicine uses cardamom for treating stomachaches, constipation, diarrhea, and other digestive difficulties. Cardomon has been traditionally used as an antispasmotic.
Throw Me a Lifesaver! |
Devra Davis
See book keywords and concepts |  As open sewers stopped flowing into local rivers, refrigeration provided more fresh fruits and vegetables, and workplaces stopped burning wastes in cities, deaths from once fatal infections like tuberculosis and typhoid dropped in industrialized nations. Chronic illnesses also can have broad social roots in both developed and developing countries. Just having the bad luck to grow up in a place downstream from heavy industry can add to this cancer burden. |
Brigitte Mars, A.H.G.
See book keywords and concepts | | In addition to its ability to ward off or mitigate illness, echinacea is used in the treatment of abcess, acne, allergy, blood poisoning, boils, bronchitis, cancer, Candida, chicken pox, chronic fatigue, colds, diphtheria, ear infection, eczema, fever, flu, gangrene, herpes, laryngitis, Lyme disease, lymphatic congestion, mastitis, measles, mumps, pneumonia, prostatitis, scarlet fever, sinusitis, smallpox, snakebite, sore throat, tonsillitis, tuberculosis, typhoid, and urinary tract infection. It also can lessen the side effects of vaccinations. |
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