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Human genes

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Emphasis should be placed on developing systems that use human genes, enzymes, cells, or tissues. Since most of the present short-term tests detect DNA reactive compounds, new methods are needed for screening chemicals for nongenotoxic endpoints such as cell proliferation, hormonal effects, receptor mediated events, and effects on cell-cell interactions, gene expression, differentiation, and apoptosis (programmed cell death). Great promise exists for the use of transgenic mice.

Food Revolution: How your diet can help save your life and our world

John Robbins
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Kimbrell, like many who share his concerns, is outraged: "We didn't get to vote on whether to take human genes and put them in animals, which they're doing through genetic engineering. . . . Do we really want unlimited genetic engineering of humans, of animals, of plants? Do we really want our generation and the generations to come after us to view the entire animal kingdom as so many machines to be re-programmed, cloned, and patented?
We're taking human genes and putting them into salmon. We're taking genes from bacteria and from rats and putting them into broccoli. The Roundup Ready varieties that in 1999 made up more than half of the entire U.S. soybean crop and a third of the entire U.S. corn crop contain genes from viruses and petunias. It is this crossing of, and violation of, Nature's species barriers that makes the process unprecedented and uniquely powerful. It is also, however, what makes it uniquely dangerous. Nature has not made it easy to cross species boundaries.

Living Downstream

Sandra Steingraber
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They are biological markers, and, defined most plainly, they are indicators of physical damage caused by the interplay between human genes and environmental carcinogens. As such, biological markers serve as both signals of past exposure and predictors of future cancers. Adducts, formed by mutation-inducing chemicals that adhere to DNA, are one type of marker. As discussed in Chapter Six, the tissues of beluga whales living in contaminated stretches of the St. Lawrence River display high concentrations of benzo[a]pyrene adducts.

The Omega Diet: The Lifesaving Nutritional Program Based on the Diet of the Island of Crete

Artemis P. Simopoulos, M.D., and Jo Robinson
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During this long period of evolution, human genes became adapted to the balance of EFAs found in wild plants and game. According to an expert in the field of evolutionary nutrition, Boyd Eaton, M.D., from Emory University: "The principles of evolutionary adaptation suggest that if a dietary pattern is maintained within a lineage for nearly two million years, it must be optimal."1 The fats eaten by early humans are just as optimal for us today because our genes are virtually identical to theirs.

Dangerous Grains: Why Gluten Cereal Grains May Be Hazardous To Your Health

James Braly M.D. and Ron Hoggan M.A.
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Research into human genes now reveals that non-celiac gluten sensitivity, or immune reactions to gluten, may affect as many as 90 million Americans. The evidence suggests that these gluten-sensitive individuals face many of the same hazards associated with untreated celiac disease. They, too, have likely never suspected the underlying cause of their disease or how easily it could be prevented, halted, and often reversed. Gluten sensitivity is much more common, yet it is sought and diagnosed even less frequently than celiac disease.

Life Without Bread

Christian B. Allan and Wolfgang Lutz
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Scientists are continually discovering more and more mutations in human genes that are associated with various diseases. Could some of these be due to too much carbohydrate in our diet? The answer is almost certainly yes. Why haven't humans been able to adapt to this onslaught of high-carbohydrate nutrition? During the ice ages, humans lived on a diet consisting exclusively of meat and other parts of the animal. The rigorous conditions of selection, which prevailed during glacial periods, must have led to complete adaptation of human metabolism to a diet of animal foods.

The Green Pharmacy Anti-Aging Prescriptions: Herbs, Foods, and Natural Formulas to Keep You Young

James A. Duke, Ph.D.
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Another advantage of eating fresh foods is that you avoid synthetic preservatives, genetically engineered foods, and animal-plant cross-species hybrids, all of which are unfamiliar to human genes. It may be months, years, even decades before we realize how these high-tech foods can harm us. I suspect that healthwise, their batting averages will be about the same as those of synthetic pharmaceuticals. (As I mention in chapter 2, more than half of all medications are found to have serious side effects after they've been approved.

The Omega Diet: The Lifesaving Nutritional Program Based on the Diet of the Island of Crete

Artemis P. Simopoulos, M.D., and Jo Robinson
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Paleolithic era, a mere 40,000 to 15,000 years ago, is believed to be negligible. This means that when we're sitting down to lunch, our stone-age bodies "expect" to be fed the same types and ratios of fat that nourished our cave-dwelling ancestors. When we eat French fries cooked in partially hydrogenated vegetable oil instead of wild plants; or wolf down a fat-laden hamburger heaped with mayonnaise instead of meat from a lean, free-ranging game animal, our bodies register the insult.

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