J. Douglas Bremner
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 For example, vitamin E has been shown in animal studies to reduce free radicals that cause oxidative stress in animal models of atherosclerosis. Based on studies like this many scientists have had high hopes that vitamins would prevent heart disease as well as other diseases like cancer. In fact, the studies that have been done, which I discuss later in this chapter, show that, if anything, they have the opposite effect.
Most sober scientists who pay attention to the data have come to the conclusion that vitamins and supplements do not prevent heart disease and cancer. |
| In addition, scientists are not sure that removal of free radicals by antioxidant agents is necessarily a good thing; one theory is that by doing so the immune system becomes less vigilant and more likely to miss cancerous cells, thereby increasing the risk of cancer.
However, once people were convinced that antioxidants could help prevent cancer and heart disease and that antioxidants could be obtained through vitamins, it became fixed in their minds. |
Erich Grotewold
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 Green tea, black tea, and EGCG were shown to block the production of oxygen free radicals derived from the cooked meat mutagen 2-amino-3-methylimidazo[4,5-fJquinoline (IQ) in the presence of a NADPH-cytochrome P450 reductase (Hasaniya et al., 1997). These results support an antioxidant role of catechins in their direct interaction with DNA radicals. |
| Chemopreventive studies have demonstrated that the mechanisms of action of phytochemicals and nutraceuticals in the prevention of cancer go beyond the antioxidant activity scavenging of free radicals; regulation of gene expression in cell proliferation, oncogenes, and tumor suppressor genes; induction of cell cycle arrest and apoptosis; modulation of enzyme activity in detoxification, oxidation, and reduction; stimulation of the immune system; and regulation of hormone metabolism. |
Dr Ron Roberts
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 It has been recognised as an antioxidant, protecting vulnerable chemicals in the body from being destroyed by free radicals. It protects cells of the body from damage by environmental pollution.
Vitamin E is found in many foods, but wheatgerm, almonds and vegetable oils are particularly rich in it.
Zinc
Zinc is a part of many enzymes in the body and is needed for the formation of proteins and insulin. It is also an all-round valuable nutrient for the body's immune system. It stabilises the blood and maintains the acid/alkaline balance of the body. |
Jonny Bowden, Ph.D., C.N.S.
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 Remember that free radicals can and do damage collagen and connective tissue, and the antioxidant activity of vitamin C helps protect against this damage all the while helping collagen synthesis.) And a paper published in Arthritis and Rheumatism that looked at 640 human participants from the Framingham Osteoarthritis Cohort Study found a threefold reduction in the risk of osteoarthritis progression for those with higher intakes of vitamin C. This also translated into a reduced risk of cartilage loss. |
Ron Garner
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 Ionized Water
Proponents of ionized water emphasize its antioxidant properties—its ability to neutralize millions of free radicals (unpaired, unstable electrons) in the body and thus slow down the aging process. Think of "antioxidant" as an anti-rusting agent. Ionized water is also alkaline. However, ionized water lacks biophotonic activity and cannot hold its molecular structure for long. It does not meet the definition of structured and energized water. |
Tom Bohager
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 These steps include eating a well-balanced diet high in vitamins, minerals, antioxidants, and nutrients; regular exercise; stress management; nutritional support of the hormonal and immune systems; and the addition of enzymes and supplemental nutritional products to optimize digestion and absorption of nutrients and improve the body's ability to eliminate free radicals. I also strongly recommend managing calorie intake, fasting four times a year, and eating plenty of raw food (see the nearly ideal diet on page 31). |
Michael Pollan
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 Several of the body's routine processes, including cell metabolism and the defense mechanism of inflammation, produce "oxygen radicals"—atoms of oxygen with an extra unpaired electron that make them particularly eager to react with other molecules in ways that can create all kinds of trouble. free radicals have been implicated in a great many health problems, including cancer and the various problems associated with aging. (Free-radical production rises as you get older.) Antioxidants like vitamin C harmlessly absorb and stabilize these radicals before they can do their mischief. |
Bill Sardi
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 Is it pesticides, industrial chemicals, electromagnetic fields, acidity, germs, oxygen free radicals, hormones, or all of these?
An argument can be made for all of the above causes. But the pervasive factor involved in the vast majority of cancer is aging.
No matter how efficient we may become at delivering health care, we must also seek to reduce demand by keeping people from developing diseases in the first place. |
| Nutrition & Cancer 48: 1-5, 2004]
Fiber from bran contains a potent iron chelator (attaching agent) called phytate (IP6) which would negatively affect the increased acidity and iron absorption by binding the iron so it cannot create free radicals that damage tissues and create gene mutations. [Nutrition Cancer 19:1 1-9, 1993; Anticancer Research 9: 1477-82, 1989]
Oxidation (spoilage) of fats
Control Iron Saturated Saturated fat fat + iron l__I__J
It is interesting to note that beef induces, while bran prevents, the formation of intestinal polyps, as demonstrated in an animal study. |
Marshall Editions
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 Supplements: Proteolytic enzymes destroy free radicals, which inhibit healing, and proteins involved in the inflammatory process. Take three tablets or capsules between meals. Vitamin C is required for the formation of connective tissue and to combat free! radicals. Essential fatty acids such as flaxseed and fish oil reduce inflammation and promote tissue healing. Take 5 g of fish oils a day or 1-2 tbsp of flaxseed oil. Take 1,500 mg off glucosamine sulfate a day to provide the raw material for the body to manufacture ligaments and tendons. |
| Also take 400 IU of vitamin E with mixed tocopherols daily as it is a powerful antioxidant that helps destroy free radicals, which inhibit healing. By protecting the cells, vitamin E promotes immune system efficiency. Colloidal silver is another potent natural antibiotic. Take 1 tsp a day orally or use it topically around the nipple.
Herbs: Herbs can be used to increase circulation, reduce inflammation, and relieve pain due to mastitis. Ground fenugreek seeds can be applied as a hot pack to increase protein absorption and promote blood building. Fenugreek is also very beneficial as a tea. |
| Antioxidants should be taken to help the body rid cells of free radicals, which can damage healthy tissue and eventually cause more harm. Vitamin C (taken at 2,000-4,000 mg a day in divided doses), alpha lipoic acid (100-200 mg a day), coenzyme Q10 (60-100 mg a day), and vitamin E (400 IU a day) are additional supplements that may be helpful. N-acetyl cysteine (NAC) also helps to detoxify the body and rejuvenate the lungs. Take 500-1,000 mg a day. Also take 10-20 mg a day of zinc, which is another nutrient that is heavily depleted in smokers, along with 4 g of fish oils a day. |
| Several studies have suggested that treatment with antioxidants that help rid the body of free radicals (harmful by-products of the oxidative process) may protect against some types of shock. Other nutrients may also be protective. L-Carnitine may be helpful in treating cardiogenic, septic, and hypovolemic shock. Take 500 mg three times a day. Take 100 mg twice a day of coenzyme Q10 (CoQ10), an antioxidant that may be beneficial in treating hypovolemic and septic shock and may improve blood flow. |
| Supplements: Vitamin A nourishes the skin and destroys free radicals, which can harm cells in the body. Take 50,000 IU thoughout the day, but do not take more than 10,000 IU a day if you are pregnant. Vitamin E aids in tissue repair and helps heal scar tissue. Take 400 IU a day. Also take 4,000 mg of vitamin C throughout the day to help with tissue repair of the skin.
Herbs: Calendula cream has been used for many years to soothe sunburns. Apply a small amount of a cream containing calendula two to three times a day. Using oatmeal can also heal and cool the skin. |
Elaine Magee
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 Next, a free-radical "chain reaction" effect can take place: Once the lipids on the cell wall are oxidized, a door is essentially opened that allows more free radicals to enter the cell, which leads to damage of the cell's internal components.
3. DNA, the genetic code that provides the cell with instructions on how to grow and reproduce, may become damaged.
4. The cell, receiving garbled instructions from damaged DNA, becomes more likely to grow incorrectly, thus setting the stage for cancer.
5. |
| Antioxidants are nutrients that help defend the body against free radicals and the damage they cause. When confronted by a free radical, an antioxidant will pair with the oxygen molecule's extra electron, thereby rendering it harmless. |
| Once inside the cell, free radicals may damage DNA and other parts of the cell that help it function properly. Similar to the DNA damage associated with radiation, free-radical damage has been associated with cancer.
POLYPHENOL FAMILY
Polyphenols are the mother of all phytochemical families, containing a whopping 2,000-plus compounds. Polyphenols give many fruits and vegetables their blue, red-blue, or violet colors. This amazing family is basically divided into two subgroups, phenolic acids and flavonoids. |
| They also found that catechins, when combined with two other phytochemicals in apples, prevented the oxidation of free radicals five times greater than expected. The phenolic phytochemicals in apple peel account for the majority of the antioxidant and antiproliferating activity noted in apples.
Eat at least an apple a day to help keep breast cancer away? In a recent lab study at Cornell, researchers found that breast tumor incidence was reduced by 17 percent when rats were fed the human equivalent of one apple a day over 24 weeks and 39 percent when fed the human equivalent of three a day. |
Jack Challem
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 They increase the production of harmful molecules known as free radicals, which play a role in virtually every disease process. Trans fats also reduce blood vessel tone and flexibility, which ends up stiffening blood vessels and reducing circulation. The same mechanism seems to interfere with how men gain erections, so trans fats are likely involved in causing erectile dysfunction. |
Tom Bohager
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| The spots tend to fade or disappear, however, when the liver and blood are cleansed or when the body's ability to remove free radicals is improved through improved immune function and enzyme production. Causes of this condition include excessive sun exposure, compromised liver function, the ingestion of rancid oils, a relatively poor diet, and lack of exercise.
Recommendations include liver detoxification, the addition of enzymes to a well-balanced diet, and supplemental nutritional products to improve one's overall digestion and absorption of nutrients. |
Bill Sardi
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| The major "players"on the opposing team are "free radicals"known as singlet oxygen, hydrogen peroxide, superoxide and hydroxyl radical. Here's how they line up, and how the human body defends against them.
The antioxidant defense force works as a team. A gap in the defense force, just like a player missing on a football team, means there is a weakness that can result in damage to DNA and eventually cause cancer. The antioxidant team has three layers of defense. |
Tom Bohager
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| Therefore, using enzymes to support digestion, the absorption of nutrients, the functioning of the immune system, the elimination of free radicals, and balanced pH levels throughout the body can help with this problem. |
| These enzymes prevent damage caused by certain types of free radicals.
Symptoms of free radical damage (necessitating dietary antioxidant therapies) can include but are not limited to headaches, frequent or chronic infections, palpitations, neck spasms, back pain, inability to relax, chronic allergies, diarrhea, nausea, heavy metal toxicity, and chronic yeast infections or candidiasis.
Laboratory studies are demonstrating that ingesting higher levels of antioxidants can increase life expectancy. |
| Purpose: To help support immune function and assist in removing viruses, fungal forms, toxins, bacteria, and heavy metals
Each capsule should contain approximately:
Enzymes can support the digestion and absorption of nutrients; fight the effects of free radicals in the body (particularly if the enzymes are proteases) improve pH balance; and reduce inflammation, which can be a side effect of free radical damage. |
Mehmet C. Oz., M.D. and Michael F. Roizen, M.D.
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 Atrial fibrillation is frequently caused by inflammation of the heart wall, and the damage is done by those oxygen free radicals produced by inefficient mitochondria. Arrhythmias can also be caused by a number of other things, including pressure on the walls of the atria or hormonal
Figure Z.3 Bftd $83t Irritation caused by inflammatory cells in the right and left atrial chambers of the heart makes the wall swell and electrical circuits short-circuit. The abnormal heart rhythms then cause blood to pool, so clots form, which can lead to strokes.
The Chelation Sensation? |
John R. Smythies
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| Technically, compounds that are short of electrons are called free radicals. The superoxide ion and the hydroxyl radical are free radicals. Thus, reactive oxygen species include both oxygen-derived free radicals and compounds like hydrogen peroxide that are not themselves free radicals but that easily generate them. Left free to react in the body's tissues, reactive oxygen species will attack and damage key molecules in the body, such as fats, proteins, and DNA?the molecule that carries genetic information. |
Jack Challem
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| Antioxidants and certain vitamins, which we'll discuss in chapter 10, can neutralize free radicals.)
What You Need to Know about Insulin
Insulin is commonly regarded as the hormone that regulates blood-sugar levels, although it does far more than this. Biologically, it's one of the most ancient of all hormones.
In fact, insulin is an extremely potent anabolic hormone, meaning that it promotes the production of new tissue. |
Mehmet C. Oz., M.D. and Michael F. Roizen, M.D.
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| By being aware and taking steps to protect yourself against many of the Major Agers that we have already discussed, such as toxins, infections, mitochondrial damage from oxygen free radicals, and genetic defects. In addition, take these steps to help prevent the birth (and spread) of cancer cells.
YOU Tip: Get the Aspirin Advantage. One of the greatest things you can do for your health takes literally a half second. If that's not incentive, we don't know what is. A half second a day can translate into extra years of life. |
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