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Flavanols

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Cancer & Natural Medicine: A Textbook of Basic Science and Clinical Research

John Boik
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In France, where much of the basic research on flavanols has taken place, they are termed "procyanidols" or in French "oligomeres procyanidoliques", or OPC. The abbreviation OPC is now used in many countries to refer to proanthocyanidins. The distribution of these compounds vary between plant species.

Textbook of Natural Medicine 2nd Edition Volume 2

Michael T. Murray, ND
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The different forms of catechin and epicatechin, and their glycosides and esters, constitute an interesting and clinically valuable group of flavanols. These flavan-3-ols readily undergo epimerization (interconversion between chemically identical but sterically different forms) during which interconversion of the (+) and (-) forms is possible. These compounds are very strong antioxidants, particularly against the hydroxyl radical-induced lipo-peroxidation characteristic of alloxan-induced diabetes and many hepatotoxins.

Cancer & Natural Medicine: A Textbook of Basic Science and Clinical Research

John Boik
See book keywords and concepts
The term pycnogenol means "that which creates condensation," and refers to the tendency of flavanols to create dimers (two identical compounds joined together), oligomers (a few joined together), and polymers (many joined together). One group of flavanol dimers and oligomers are termed proanthocyanidins, and are discussed below in item 5. 3) Flavones and Flavonols. Flavones and flavonols are the most widely occurring flavonoids. Although several hundred flavonol aglycones are known, only quercetin, kaempferol, and myricetin are widely distributed.

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