cancer

Grape seed extract targets cancer cells by damaging DNA repair pathway

Tuesday, February 07, 2012 by: John Phillip
Tags: grape seed extract, cancer cells, DNA

eTrust Pro Certified

Most Viewed Articles
Popular on Facebook
CDC issues flu vaccine apology: this year's vaccine doesn't work!
The five biggest lies about Ebola being pushed by government and mass media
Ultraviolet light robot kills Ebola in two minutes; why doesn't every hospital have one of these?
Tetanus vaccines found spiked with sterilization chemical to carry out race-based genocide against Africans
Biologist explains how marijuana causes tumor cells to commit suicide
Healthy 12-year-old girl dies shortly after receiving HPV vaccine
Companies begin planting microchips under employees' skin
The best way to help your body protect itself against Ebola (or any virus or bacteria)
NJ cops bust teenagers shoveling snow without a permit
Cannabis dissolves cancerous tumor in young infant, deemed a 'miracle baby' by physician
Russia throws down the gauntlet: energy supply to Europe cut off; petrodollar abandoned as currency war escalates
W.H.O. contradicts CDC, admits Ebola can spread via coughing, sneezing and by touching contaminated surfaces
McDonald's in global profit free fall as people everywhere increasingly reject chemically-altered toxic fast food
Top ten things you need to do NOW to protect yourself from an uncontrolled Ebola outbreak
Chemotherapy kills cancer patients faster than no treatment at all
FDA targets Dr. Bronner's Magic Soaps for sharing health benefits of coconut oil
U2's Bono partners with Monsanto to destroy African agriculture with GMOs
Why flu shots are the greatest medical fraud in history

Delicious
(NaturalNews) Researchers from the Colorado Cancer Center reporting in the prestigious journal Carcinogenesis explain the unique mechanism exerted by grape seed extract to destroy cancer cells that target the head and neck. More than half a million people worldwide will fall victim to squamous cell carcinoma involving the head and neck, and 12,000 will die in the US alone. In an experimental model using mice, scientists have found that grape seed extract triggers DNA damage in the cancer cells and inhibits the necessary repair mechanism used by the cells to regenerate and multiply.

Grape seed extract has been the subject of multiple studies that demonstrate the polyphenols ability to support brain health, improve cognition and lower the risk of dementia. Regular consumption of red grapes or supplementation with grape seed extract is now found to be an important ally in the war against cancer.

Grape Seed Extract Lowers the Growth Rate of Certain Cancers by up to 67%

The lead researcher, Dr. Rajesh Agarwal and his team determined that supplementing mice with grape seed extract (GSE) reduced the growth of certain cancers by up to 67%, lowered the rate of progression of deadly tumors and DNA damage while inducing apoptosis (programmed cell death) of the cancer cells. Mice have been used to study specific cancer cell lines because they parallel tumor progression and metastasis in a manner similar to humans.

The researchers found that GSE created an environment that is unfavorable for cancer cell growth. Cancer cells require a specific environment, blood supply and metabolic nutrients to be able to propagate. If any of these pathways are disrupted, cancer cell death occurs. The scientists commented "Cancer cells are fast-growing cells... not only that, but they are necessarily fast growing. When conditions exist in which they can't grow, they die."

The team determined that GSE both damages cancer cells' DNA (via increased reactive oxygen species) and stops the pathways that allow repair. Most important, they found there was no toxicity from supplementation. GSE killed the cancer cells by knocking out one of several vulnerable paths necessary for growth, and left the healthy tissue untouched. Dr. Agarwal concluded "I think the whole point is that cancer cells have a lot of defective pathways and they are very vulnerable if you target those pathways. The same is not true of healthy cells."

Though this study focused specifically on GSE as a therapeutic agent for cancers of the head and neck, prior research has shown the natural compound was effective against leukemia and tumors affecting the skin, breast, colon, lung, stomach and prostate. Nutrition experts recommend supplementation with an organically harvested grape seed extract (150 mg per day) to support brain health and fight cancerous tumor development.

Sources for this article include:

http://carcin.oxfordjournals.org

http://www.sciencedaily.com/releases/2012/01/120127140939.htm

http://www.nutraingredients.com

About the author:
John Phillip is a Certified Nutritional Consultant and Health Researcher and Author who writes regularly on the cutting edge use of diet, lifestyle modifications and targeted supplementation to enhance and improve the quality and length of life. John is the author of 'Your Healthy Weight Loss Plan', a comprehensive EBook explaining how to use Diet, Exercise, Mind and Targeted Supplementation to achieve your weight loss goal. Visit My Optimal Health Resource to continue reading the latest health news updates, and to download your copy of 'Your Healthy Weight Loss Plan'.

Join over four million monthly readers. Your privacy is protected. Unsubscribe at any time.
comments powered by Disqus
Take Action: Support NaturalNews.com by linking back to this article from your website

Permalink to this article:

Embed article link: (copy HTML code below):

Reprinting this article:
Non-commercial use OK, cite NaturalNews.com with clickable link.

Follow Natural News on Facebook, Twitter, Google Plus, and Pinterest

Colloidal Silver

Advertise with NaturalNews...

Support NaturalNews Sponsors:

Advertise with NaturalNews...

GET SHOW DETAILS
+ a FREE GIFT

Sign up for the FREE Natural News Email Newsletter

Receive breaking news on GMOs, vaccines, fluoride, radiation protection, natural cures, food safety alerts and interviews with the world's top experts on natural health and more.

Join over 7 million monthly readers of NaturalNews.com, the internet's No. 1 natural health news site. (Source: Alexa.com)

Your email address *

Please enter the code you see above*

No Thanks

Already have it and love it!

Natural News supports and helps fund these organizations:

* Required. Once you click submit, we will send you an email asking you to confirm your free registration. Your privacy is assured and your information is kept confidential. You may unsubscribe at anytime.