Home
Subscribe (free)
About NaturalNews
Contact Us
Write for NaturalNews
Media Info
Advertising Info
Breast cancer

FDA Questions Effectiveness of Breast Cancer Drug

Friday, August 13, 2010 by: Megan Rostollan
Tags: breast cancer, drugs, health news

Most Viewed Articles
http://www.naturalnews.com/029454_breast_cancer_drugs.html
Delicious
diaspora
Print
Email
Share

(NewsTarget) The Food and Drug Administration went public with its doubts about the effectiveness of a relatively new breast cancer drug (1). This drug was approved in 2008 after a clinical trial showed that it slowed the progression of breast cancer tumors. Initially the drug appeared promising and it was approved for treatment of breast, lung, colon, kidney, and brain cancers. The drug was the top selling cancer treatment last year for the manufacturing company, with total sales of 5.9 billion dollars world-wide and approximately 1.2 billion of that revenue coming from its use in the treatment of breast cancer (2). Now follow-up studies are failing to show that the drug extends the lives of cancer patients and the FDA is considering withdrawing its prior recommendation of this particular drug for use in treating breast cancer.

The drug was put through an accelerated approval process back in 2008 and its continued use was contingent on later drug trials confirming its effectiveness in extending the lives of breast cancer patients. Now that this ability is in question the continued use of the drug for treating breast cancer is as well. FDA reviewers said that follow-up studies submitted to them by the pharmaceutical company failed to show that the drug extended life expectancy in breast cancer patients, saying that those studies "failed to confirm the magnitude of (progression-free survival) improvement" that was seen in earlier breast cancer trials.

Early trials showed that patients' progression-free survival rate increased by 5.5 months on the drug in question. In later studies these numbers ranged from one month to under three months, which is not considered clinically meaningful.

Additionally, patients taking the tumor-starving drug showed potentially serious side effects, which included high blood pressure, fatigue, and problems with white blood cell levels (3). Other risks include gastrointestinal perforations, blood clots, and bleeds, when the drug is combined with chemotherapy treatment; these are risks the FDA is not certain are worth the potential benefits.

The FDA asked a panel of outside experts to analyze the data on the drug, and the outcome is expected to heavily influence the FDA's final decision about the drug. It is not expected that this cancer treatment will be removed from the market entirely, but its use in treating advanced breast cancer may no longer be recommended.

References:

1.http://tinyurl.com/2dgu4uj
2.http://tinyurl.com/24x5mju
3.http://www.usatoday.com/news/health/2010-07-...


About the author

Megan Rostollan is a Certified Family Herbalist and works with her husband David, a private natural health and nutrition consultant (www.reforminghealth.com). She is also the author of a blog which can be found at NaturalHousewifery.com. Her areas of greatest interest include women's reproductive and prenatal health, as well as organic and green living and dietary and lifestyle changes.



Join the Health Ranger's FREE email newsletter
Get breaking news alerts on GMOs, fluoride, superfoods, natural cures and more...
Your privacy is protected. Unsubscribe at any time. | Learn more...

comments powered by Disqus

The War on Independent Media Has Begun

A coordinated censorship attack is being waged against the entire independent media by Google, YouTube and Facebook. After we were banned by Google for nearly a week, now Facebook is deliberately blocking the sharing of our stories to further censor our important reporting for human freedom and medical choice. Soon, the only way we will be able to reach you is via email, and Google is sometimes blocking our email delivery to gmail users.

Enter your email address below to subscribe to our email announcement list (but don't use gmail). Your privacy is protected and you can unsubscribe at any time. If you don't join our email list, you may never see our valuable content again via Facebook, Google or YouTube. CENSORSHIP has now reached EXTREME levels across the 'net. The truth is being suffocated. Subscribe now if you want to escape the delusional bubble of false reality being pushed by Google and Facebook.

Once you click subscribe, we will send you an email asking you to confirm your free subscription.