Low Leptin Levels Increase Risk of Age-Related Mental Decline

Sunday, December 27, 2009 by: Dr. David Jockers
Tags: leptin, mental decline, health news

eTrust Pro Certified

Most Viewed Articles
Popular on Facebook
CDC issues flu vaccine apology: this year's vaccine doesn't work!
The five biggest lies about Ebola being pushed by government and mass media
Ultraviolet light robot kills Ebola in two minutes; why doesn't every hospital have one of these?
Tetanus vaccines found spiked with sterilization chemical to carry out race-based genocide against Africans
Biologist explains how marijuana causes tumor cells to commit suicide
Companies begin planting microchips under employees' skin
The best way to help your body protect itself against Ebola (or any virus or bacteria)
NJ cops bust teenagers shoveling snow without a permit
Russia throws down the gauntlet: energy supply to Europe cut off; petrodollar abandoned as currency war escalates
McDonald's in global profit free fall as people everywhere increasingly reject chemically-altered toxic fast food
W.H.O. contradicts CDC, admits Ebola can spread via coughing, sneezing and by touching contaminated surfaces
Top ten things you need to do NOW to protect yourself from an uncontrolled Ebola outbreak
Chemotherapy kills cancer patients faster than no treatment at all
FDA targets Dr. Bronner's Magic Soaps for sharing health benefits of coconut oil
U2's Bono partners with Monsanto to destroy African agriculture with GMOs
Why flu shots are the greatest medical fraud in history
Governments seize colloidal silver being used to treat Ebola patients, says advocate
Flu vaccine kills 13 in Italy; death toll rises

(NaturalNews) Researchers at Boston University School of Medicine recently discovered that individuals with lower levels of circulating leptin had an increased risk of dementia and Alzheimer Disease (AD).

Leptin, a hormone produced by the visceral and subcutaneous adipose (fat) tissue, is critical in regulating caloric intake and fat stores. As calories are consumed this powerful hormone is secreted into the circulatory system where it makes its way up to the hypothalamus. The hypothalamus contains specialized receptors within the metabolic control center that respond to leptin. Leptin's effect is to cause feelings of satiety and to increase energy expenditure, particularly from stored body fat.

Chronic inflammation from dietary stress, heavy metal toxicity, or environmental pollutants can damage the hypothalamaic leptin receptors, causing a condition called leptin resistance. Leptin resistance is characterized by an inability for the hypothalamus to respond to high circulating insulin levels. This causes increased appetite and weight gain.

The new study suggests that leptin plays an important role in the hippocampus, a critical area that functions to facilitate memory processes. Results of the study showed that individuals with the highest levels of leptin had a 6% risk of developing AD during 12 years compared with a 25% risk for those with the lowest leptin levels.

"It's interesting and exciting because it's a new pathway that was not previously suspected to be directly involved in AD in humans," said lead author Sudha Seshadri, MD, associate professor of neurology, Boston University School of Medicine in Massachusetts.

Leptin is known to play a critical role in energy metabolism and has also been shown to stimulate angiogenesis (arterial formation). It is through this mechanism, by stimulating the hippocampus and increasing blood supply, that many believe the study results were produced.

This new pathway gives us a better understanding of some of the key mechanisms behind age related memory loss and the increase in these conditions over the last 20 years. Leptin levels are influenced heavily by diet and lifestyle, which thus far have been relatively ignored by mainstream medicine.

For example, several studies have shown that high fructose intake causes leptin resistance and elevated triglycerides in rats. High fructose corn syrup is virtually ubiquitous in the processed foods that make up much of the American diet.

Balance Leptin Levels Naturally:

1.Reduce sugar & grain consumption: Sugar, high fructose corn syrup and heavy doses of grains such as wheat, oats, rice, & starchy vegetables will increase leptin resistance, while also limiting the body's ability to stimulate leptin release.
2.Avoid High Omega 6 fats and Trans-Fats: These fats inflame the body.
3.Healing Diet: Build your meals around non-starchy vegetables and healthy fats such as avocados, extra-virgin coconut & olive oils, grass-fed meat and free-range eggs, almonds, brazil nuts, pecans, walnuts, hemp, flax, & chia seeds.
4.Train For Maximal Fat Burning: High intensity exercise for short duration stimulates large secretions of human growth hormone, which enhances fat burning mechanisms and helps to modulate leptin levels.
5.Sleep Well: Leptin levels typically rise during sleep. Studies have shown that sleep deprivation decreases circulating leptin levels and leads to insensitivity, over-eating, weight-gain and mental decline. Best to eat 3-4 hours before bed and be in bed for sure by 11pm.

1. JAMA. 2009;302:2565-2572.
5."Fructose Sets Table For Weight Gain Without Warning". Science News. Science Daily. 2008-10-19. http://www.sciencedaily.com/releases/2008/10.... Retrieved 2008-11-15.
6.Vasselli JR (November 2008). "Fructose-induced leptin resistance: discovery of an unsuspected form of the phenomenon and its significance. Focus on "Fructose-induced leptin resistance exacerbates weight gain in response to subsequent high-fat feeding," by Shapiro et al.". Am. J. Physiol. Regul. Integr. Comp. Physiol. 295 (5): R1365-9. doi:10.1152/ajpregu.90674.2008. PMID 18784330.
7.Shapiro A, Mu W, Roncal C, Cheng KY, Johnson RJ, Scarpace PJ (November 2008). "Fructose-induced leptin resistance exacerbates weight gain in response to subsequent high-fat feeding". Am. J. Physiol. Regul. Integr. Comp. Physiol. 295 (5): R1370-5. doi:10.1152/ajpregu.00195.2008. PMID 18703413.

About the author

Dr. David Jockers owns and operates Exodus Health Center in Kennesaw, Ga. He is a Maximized Living doctor. His expertise is in weight loss, customized nutrition & exercise, & structural corrective chiropractic care. For more information go to www.exodushc.com To find a Maximized Living doctor near you go to www.maximizedliving.com

Join over four million monthly readers. Your privacy is protected. Unsubscribe at any time.
comments powered by Disqus
Take Action: Support NaturalNews.com by linking back to this article from your website

Permalink to this article:

Embed article link: (copy HTML code below):

Reprinting this article:
Non-commercial use OK, cite NaturalNews.com with clickable link.

Follow Natural News on Facebook, Twitter, Google Plus, and Pinterest

Colloidal Silver

Advertise with NaturalNews...

Support NaturalNews Sponsors:

Advertise with NaturalNews...


Sign up for the FREE Natural News Email Newsletter

Receive breaking news on GMOs, vaccines, fluoride, radiation protection, natural cures, food safety alerts and interviews with the world's top experts on natural health and more.

Join over 7 million monthly readers of NaturalNews.com, the internet's No. 1 natural health news site. (Source: Alexa.com)

Your email address *

Please enter the code you see above*

No Thanks

Already have it and love it!

Natural News supports and helps fund these organizations:

* Required. Once you click submit, we will send you an email asking you to confirm your free registration. Your privacy is assured and your information is kept confidential. You may unsubscribe at anytime.