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"Reduction of particle exposure by filtration of re-circulated air for only 48 hours improved the microvascular function (MVF) in healthy elderly citizens," said Professor Steffen Loft, M.D., D.M.Sc., of the Institute of Public Health in Copenhagen. "This suggests that indoor air filtration represents a feasible means of reducing cardiovascular risk." Abnormal function of the inner lining of small vessels is known to be a predictor of dangerous or possibly fatal cardiovascular events. The researchers measured MVF and ambient airborne particles in the homes of 21 non-smoking couples aged 60-75 who lived close to heavily trafficked roads. Each couple used air purifiers for two 48-hour periods. During one period, the purifier was equipped with a HEPA filter, and during the other, it ran without it, so that each individual served as his or her own control. The size distribution and number concentration of indoor air particles in each home were continuously monitored. The researchers then assessed each individual's MVF using a noninvasive finger sensor. Several secondary endpoints were studied in blood and urine samples to assess possible mechanisms of action: markers of inflammation, hemostasis, and oxidative stress. "Our main finding was a significant improvement in the function of small finger blood vessels after reduction of indoor air particles. This effect most likely indicates a general improvement in the function of the inner lining of small vessels, including those supplying the heart," said Dr. Loft. The researchers found that HEPA filtration removed about 60 percent of the ultrafine, fine and coarse air particles in homes, and was associated with an 8.1 percent improvement in individual MVF. "We expected that removing air particles with the HEPA filters would result in improvement of MVF but we were heartened and surprised by the extent it did, considering the modest levels of particles in the indoor air of the homes of the elderly," said Dr. Loft. None of the secondary endpoints considered showed significant differences after statistical corrections, suggesting that the mechanism underlying the improvement in MVF after air filtration remains unclear, and underscoring the need for further study. "The results of this study indicate that reduction of particles in re-circulated indoor air by filtration significantly improves MVF in a healthy, non-smoking, elderly population," wrote Dr. Loft. "The improvement could not be ascribed to significant reduction in inflammation or oxidative stress by means of biomarkers." Dr. Loft and his team are now studying the effect of high levels of wood smoke on MVF in healthy subjects. They hope that the mechanisms can be better understood by means of a wider range of secondary endpoints, including expression of important genes, which they are currently developing. Looking at this study I would recommend that HEPA air filters be placed in every home. It just may help prevent children and healthy young adults from heart disease and environmental illness that are so prevalent today. Source: The study was published in the second issue for February of the American Journal of Respiratory and Critical Care Medicine, published by the American Thoracic Society. American Thoracic Society (2008, February 18). Using High Efficiency Particle Air Filters May Improve Cardiovascular Health. About the authorLeslee Dru Browning is a 6th generation Medical Herbalist & Nutritionist from the ancestral line of Patty Bartlett Sessions; Pioneer Mid-Wife & Herbalist. Leslee practiced Medical Herbalism and Nutritional Healing for over 25 years and specialized in Cancer Wellness along with Chronic Illness. She now devotes her career to teaching people, through her writing, about Natural Healing from An Herbal Perspective.Related CounterThink Cartoons:
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