(NaturalNews) Three recent clinical studies, two about cocaine addiction and one about compulsive gambling, examine the role of a simple amino acid in normalizing brain chemistry of those with addiction. Drug addiction and various forms of pathological gambling has widely ruined personal finances, family cohesiveness and health. Relapse rates are extremely high. These studies offer much hope for an inexpensive, non-toxic option for healing.
N-acetylcysteine, a form of the sulfur-containing amino acid cysteine is a precursor to the brain neurotransmitter glutamate. There is observational evidence that low levels of glutamate in the brain will increase compulsive and addictive behaviors and intensify cravings. Taking NAC by mouth has been shown to increase glutamate concentrations in the regions of the brain (the nucleus accumbens) which, when low in glutamate, promotes addictive behavior.
In the first study, 15 volunteers with a history of cocaine addiction received either 600 mg of NAC
or placebo every 12 hours for 2 days. The test subjects taking NAC were significantly less likely to scan the internet for cocaine-related news than those on placebo, and the NAC group also revealed in a questionnaire an impressive reduction in cocaine craving (1).
A second study conducted by the same investigators, gave 23 cocaine addicts who were seeking treatment 600, 1200, or 1800 mg of NAC twice daily for 4 weeks. Sixteen patients completed this study and cocaine use dropped dramatically. The amount of NAC didn't seem to matter, and no side effects were noted. Before seeking help, the 16 patients who stuck with the 4 week program, on average, decreased their cocaine use from 8 days out of the month before starting the NAC, to only 1 day during the month taking NAC (2).
This sounds great (85% reduction in cocaine use) but keep in mind that these patients sought treatment. The will to arrest a destructive behavior is key to successful therapy. NAC may help correct brain chemistry, for less than $2 per day, and cement the desire to quit with the ability to
modify behavior.
The third study looked at offering up to 1800 mg daily of NAC to those wanting to relieve themselves of their addiction to gambling. A positive response to treatment was defined as at least a 30% decrease in parameters measured by a tool called "Yale Brown Obsessive Compulsive Scale Modified for Pathological Gambling." The average effective dose of NAC was 1500 mg daily. Sixteen gamblers completed the study and their scores improved 42% (3).
Earlier studies have suggested that there is a biochemical component to addiction. The beneficial effects of glutamine, B vitamins, lithium, and dietary modifications have been shown for people addicted to alcohol. The field of optimizing brain chemistry is in its infancy. Hopefully future research will continue to focus on safe, natural, inexpensive and effective nutrients to provide much-needed help for the millions of people who want to quit, but haven't yet.
References:
1. LaRowe SD, Myrick H, Hedden S, Mardikian P, Saladin M, McRae A, et al. Is cocaine desire reduced by N-acetylcysteine? Am J Psychiatry 2007;164:1115-1117.
2. Mardikian PN, LaRowe SD, Hedden S, Kalivas PW, Malcolm RJ. An open-label trial of N-acetylcysteine for the treatment of cocaine dependence: a pilot study. Prog Neuropsychopharmacol Biol Psychiatry 2007;31:389-394.
3. Grant JE, Kim SW, Odlaug BL. N-Acetyl cysteine, a glutamate-modulating agent, in the treatment of pathological gambling: a pilot study. Biol Psychiatry 2007;62:652-657.
About the authorDr Emily Kane is a practising naturopathic physician and licensed acupuncturist. For more info see www.DrEmilyKane.com
###
Related Articles
• New study finds common herbal supplement helps to reduce cocaine cravings (press release)
• The unauthorized history of Coca-Cola (satire)
• Anti-drug vaccination plan could immunize people from effects of cocaine, heroin and nicotine
• Army, Marines recruiters ran cocaine operation in Arizona
• Prescription pain killers involved in more drug overdose deaths than cocaine or heroin in the US (press release)
 |
Additional Resources:
cocaine
psychiatry
the brain
|
Take Action: Support NaturalNews.com
 Email this article to a friend
 Share this article on: NewsVine | digg | del.icio.us
Permalink to this article: http://www.NaturalNews.com/022492.html
Reprinting this article: Non-commercial OK, cite NaturalNews.com with clickable link.
|
 |
 |
Receive our Natural Health Newsletter for FREE
 Subscribe now (it's free!) to win. We randomly choose a subscriber each month to send $100 in eco-home products or a RealGoods.com gift certificate (our choice). Plus, you'll receive FREE news, articles and action alerts from NaturalNews.com editors and join over 800,000 monthly readers who report extraordinary health improvements after becoming a subscriber!
- Receive breaking news alerts on natural health solutions, renewable energy, the environment, global warming and more.
- Receive a free instant download of our $29 Secret Sources guide that reveals top sources for little-known health and diet solutions.
|
|
 |
 |
Recommended Special Report:
 Seven Words that can Change the World
by Joseph R. Simonetta
Read this special report now...
"Seven Words That Can Change the World reveals the astonishing, simple truths that have the power to forever transform our world for the better while freeing our minds from the enslavement of limiting beliefs. This is not a text for the simple-minded; it is a guiding philosophy for the mindful, intelligent few who are wise enough to seek out -- and recognize -- the higher simplicities of truly purposeful living." - Mike Adams, the Health Ranger, editor of NaturalNews.com
|
More on NaturalNews.com:
• Streaming Health Ranger Videos
• CounterThink Cartoons
• FREE Special Reports
• Podcasts
|
 |
|
 |
 |
NEW 6-CD audio set reveals amazing new protocol for reversing cancer, diabetes, obesity, heart disease and more. Click to learn more. |
 |
Own the first 8 Health Ranger Report audio programs on 6 CDs. Covers weight loss, ADHD, vaccinations, processed meats, bone health and more. Click to learn more. |
Featured Videos
Short clip on Aspartame
A short clip on aspartame from the documentary All Jacked Up.
Click here to view now...
Exclusive video on Aspartame
The dangers of aspartame! Exclusive interview footage from Cori Brackett of Sweet Remedy.
Click here to view now...
Exclusive Footage from All Jacked Up!
See interview footage featuring the Health Ranger in the upcoming junk food film, All Jacked Up.
Click here to view now...
Drug Ad Parody
See the Health Ranger's satire parody of Merck's cholesterol drug ad.
Click here to view now... |
Adderall vs. Meth
Sugar Addicts
Fidozac: Antidepressant Drugs for Dogs
|
|
Read recommendations on supplement companies, health food manufacturers and personal care product makers that you can trust. Our 100% independent review list tells you who to trust and who to avoid in the natural health industry. Click to read. |
|
Printable Version
