(NaturalNews) A type of omega-3 fatty acid called docosahexaenoic acid (DHA) may help prevent the abnormal clumping of certain proteins that leads to the development of Alzheimer's disease, according to a new study published in the
Journal of Neuroscience. The research was conducted by scientists from the University of California at Irvine and from Martek Biosciences, a corporation that makes commercially available DHA products.
Alzheimer's is a common neurodegenerative disease that occurs when lesions form in
the brain due to the clumping of beta-amyloid and tau
proteins. Two to 3 percent of people aged 65 exhibit signs of the
disease; by age 85, the percentage rises to 25 to 50 percent.
The researchers studied mice genetically predisposed to develop
Alzheimer's by feeding them one of four different diets. The mice in one group were fed a
diet similar to the typical US diet, low in
omega-3 fats and high in omega-6s. A second group was fed a diet rich in
omega-3s and supplemented with DHAs, while the other two groups were fed food rich in omega-3s and supplemented with both
DHA and omega-6s. After 9 months, the brains of the mice who had been fed the DHA
supplement had lower levels of beta-amyloid and tau proteins.
The researchers believe that DHA may interfere with the accumulation of these proteins by lowering levels of an enzyme needed to produce them.
Senior author Frank LaFerla says that the next step is to do clinical studies on humans in the early stages of Alzheimer's to see if DHA supplements have a positive effect in slowing the disease's progression. Such a study is being carried out by
Martek Biosciences.
DHA is naturally found primarily in fish. Animals produce very little of it on their own, but it is produced by microalgae from the genus Schizochytrium and tends to concentrate in the tissue of sea
animals.
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