Dietary fats reduce effectiveness of antioxidants like vitamin C

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The anti-cancer benefits of vitamin C can be dramatically reduced by intake of dietary fats, according to a new study conducted at the University of Glasgow. The results of the study, which simulated what happens in the human stomach, were presented earlier this month at the annual meeting of the Society of Experimental Biology in Glasgow.

Researchers investigated how vitamin C affects the acidification of nitrite in the stomach. This acidification can lead to production of potentially carcinogenic N-nitroso compounds related to stomach cancer. According to the European School of Oncology, stomach cancer is the fourth most frequent cancer worldwide with 800,000 new cases diagnosed every year.

Carcinogenic compounds form when nitrite, found in saliva, and nitrate in some foods mix with stomach acids. Ascorbic acid (the active component of vitamin C) protects against the formation of these compounds. The study revealed vitamin C inhibited conversion to carcinogenic compounds by approximately 99.7 percent.

Notably, the research team also found when dietary fats were added to the mix, the antioxidant properties of vitamin C were neutralized, and the carcinogenic N-nitrosamine was formed.

"These results indicate that the presence of lipid can markedly alter the protective effects of antioxidants with respect to potentially carcinogenic nitrosative chemistry occurring in the human stomach, and illustrate how a diet rich in lipids can directly influence gastric biochemistry," said lead author Emilie Combet.

Lipids are substances of the fat group and are insoluble in water. While some lipids are necessary for storing energy, others include a class of harmful trans-fatty acids found in hydrogenated oils and partially hydrogenated oils common not only in fast food but also in many products found on grocery store shelves -- including dairy products and meat. This year major cities in the U.S. are taking steps to ban trans-fats in food served in restaurants.

"This research helps explain why high-fat diets that focus on dairy products, meat products, and processed foods are so strongly correlated with cancer and heart disease," said Mike Adams, author of Grocery Warning: How to Identify and Avoid Dangerous Food Ingredients. "Many superfoods perform best when consumed during a meal that has no fats," Adams said, "But don't forget to consume healthy, plant-based fats later. Omega-3 fatty acids are essential for a healthy heart."
About the author: Mike Adams is a natural health author and technology pioneer with a passion for sharing empowering information to help improve personal and planetary health He has authored and published thousands of articles, interviews, consumers guides, and books on topics like health and the environment, reaching millions of readers with information that is saving lives and improving personal health around the world. Adams is an honest, independent journalist and accepts no money or commissions on the third-party products he writes about or the companies he promotes. In 2007, Adams launched EcoLEDs, a maker of super bright LED light bulbs that are 1000% more energy efficient than incandescent lights. He's also a noted pioneer in the email marketing software industry, having been the first to launch an HTML email newsletter technology that has grown to become a standard in the industry. Adams also serves as the executive director of the Consumer Wellness Center, a non-profit consumer protection group, and pursues hobbies such as Pilates, Capoeira, nature macrophotography and organic gardening. Known on the 'net as 'the Health Ranger,' Adams shares his ethics, mission statements and personal health statistics at www.HealthRanger.org

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