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"This PoliBlue supplement is a powerful combination of foods and nutrients for lowering cholesterol safely, naturally and with zero negative side effects," said Adams, author of "Natural Health Solutions." "Over the last three years, I have witnessed truly astounding cholesterol breakthroughs in people who simply ate blueberries. Combined with policosanol, this new concentrated supplement is, in my view, far more effective than any cholesterol medication on the market, including statin drugs, yet it has none of the side effects and is available without a prescription." According to the Wellness Resources web site, PoliBlue is made from high-quality extracts of blueberry and policosanol, both of which lower LDL (bad) cholesterol, studies indicate. This is achieved, the web site states, because the ingredients "support the natural metabolism of cholesterol and triglycerides, as well as offer nutritional support for healthy circulation." The nutrient compound pterostilbene, found in blueberries, guides cells in the human body to properly using cholesterol and tryglycerides, which supports healthy metabolism, the site says. Blueberries are also rich in anthocyanidins, antioxidants that are thought to help combat damage from free radicals. The site notes that past research suggests policosanol boosts the enzyme known as AMP-kinase. Regulation of the enzyme HMGCoA reductase is the primary means of controlling cholesterol levels, and AMP-kinase has been shown to do just that. Statin drugs, by comparison, are pharmaceuticals that inhibit the production of HMGCoA reductase in the liver, which helps clear LDL cholesterol from the blood, but unlike PoliBlue, use of the drug has numerous side effects. Adverse effects reported with statin use include muscle pain and cramps, gastrointestinal issues, renal failure (although this is rare), and liver enzyme derangements. Statins are also known to interact poorly with some other medications. A disclaimer on the site points out that health claims related to PoliBlue have not been evaluated by the FDA, and that the product is not meant as a treatment for any disease or condition. Such statements are common within the supplement industry, because, even though studies have shown that blueberries and policosanol can lower cholesterol, any supplement that claims to treat a disease must go through a series of expensive and lengthy tests and will be treated like a drug by the FDA.
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