extract

A Mushroom Extract May Impact the Body’s Immune System (press release)

Monday, October 09, 2006 by: NaturalNews
Tags: health news, Natural News, nutrition

eTrust Pro Certified

Delicious Pin It
Can the extract of a mushroom that is commonly found in the woods of North America, Asia and Europe have a beneficial impact on the human immune system? A small study using “Turkey Tail” mushroom (Trametes versicolor) extract, has found that it may.

The “Turkey Tail” mushroom is too tough to eat, but it may be ingested in the form of liquid or powdered extracts. One such extract produced by Kureha, Inc., Tokyo, Japan, is Polysaccharide Krestin® (PSK), a protein-bound polysaccharide fraction. The PSK extract has been found to have a beneficial effect in the treatment of certain types of cancers, especially when used in conjunction with chemotherapy. In order to determine its effects on the human immune system, a team of researchers sought to use a proteomic approach to identify the immunologically relevant proteins stimulated by treatment with the mushroom extract in human immune cells.

A New Study The authors of the study “Cross Validation of Influence of Polysaccharide Krestinâ (PSK) Extract of Trametes versicolor on Protein Expression in Human Primary Peripheral Blood Lymphocytes” are John S. Finnell, M.S., Daesong Yim, Ph.D., Masa Sasagawa, N.D., and Cynthia A. Wenner, Ph.D., all from the School of Natural Health Sciences, Bastyr University, Kenmore, WA; Animesh Nandi , Ph.D., Prem Gurnani, and Kevin P. Rosenblatt, M.D., Ph.D., from the Department of Pathology, University of Texas Southwestern Medical Center, Dallas, TX.

This study was funded in part by a grant from the National Institutes of Health - National Center for Complementary and Alternative Medicine (NCCAM), as well as an Institutional Seed Grant from Bastyr University.

The team will present preliminary findings during the 21st Annual Meeting of the American Association of Naturopathic Physicians (http://www.Naturopathic.org), being held August 9-12, 2006, at the Oregon Convention Center, Portland, OR.

Methodology Immune cells were isolated from blood taken from nine healthy human volunteers and were cultured in vitro. The immune cell samples were treated under three different conditions: one set with no treatment, which served as the negative control; another set treated with the PSK mushroom extract; a third set treated with phytohemagluttin (PHA), a mitogen known to stimulate activation of immune cells; and a final set treated with both the mitogen and mushroom extract, in combination. Separate portions of cell lysates and supernatants (the liquid medium in which the cells were cultured) were collected at 0, 1 and 24 hours, flash-frozen, and stored at –80°C. Samples were analyzed at pH3 on immobilized metal affinity capture (IMAC30) ProteinChip® arrays, using both low-performance and high-performance mass spectrometry (MS). Statistical analyses of low- and high-resolution MS data were cross-validated to determine whether changes in immunologically relevant proteins occurred that were attributable to treatment with the mushroom extract.

Results Statistical analysis of the spectra showed significant differential post-translational modification or expression of proteins, in the range of 1-30 kilodalton (kDa – a unit of measure of the atomic mass of the proteins), in the treated sets of cell cultures, as compared to untreated, negative control samples. Many immunologically relevant proteins, including many known to regulate immune responses, fall within the 1-30 kDa range.

Conclusions The findings from this research study suggest that protein-bound, polysaccharide-rich fractions of Trametes versicolor PSK may modulate the post-translational modification or expression of proteins in healthy human immune cells. The next step is to extract and sequence the proteins of interest to determine their specific function in immune cells. The results invite further research to determine how selected extracts of medicinal mushrooms may be effective in strengthening the body’s immune system against diseases, such as cancer.

The American Association of Naturopathic Physicians (AANP) was founded in 1985 to provide alternative methods for healing human diseases and disorders than have been traditionally offered in the United States. Members of the AANP must have graduated from one of North America’s six accredited graduate schools of naturopathic medicine.

For more information about naturopathic physicians, log on to http://www.naturopathic.org/.

Source: American Association of Naturopathic Physicians (AANP)

Get breaking news alerts on GMOs, fluoride, superfoods, natural cures and more...
Join over four million monthly readers. Email privacy 100% protected. Unsubscribe at any time.


Have comments on this article? Post them here:

comments powered by Disqus

Take Action: Support NaturalNews.com

Email this article to a friend

Permalink to this article:

Reprinting this article: Non-commercial use OK, cite NaturalNews.com with clickable link.

Embed article link: (copy HTML code below):
Most Popular
Today | Week | Month | Year

See all Top Headlines...



GET SHOW DETAILS
+ a FREE GIFT

Now Available at ShopNaturalNews.com

O3 Essentials OraJuvenate™
A powerful, cleansing dental cream for maximum oral/dental health.
New Cancer Solutions
Over 3 hours of content covering today’s best cancer tests, how to kill cancer cells and the best diets and exercise routines.
Freeze-Dried 100% Organic Whole Corn
Our freeze-drying method preserves taste, texture and nutrients better than any other food preservation method ever invented.
Fenix TK35 Flashlight
Tough, waterproof, extremely bright and it’s touted to throw an 800+ lumen beam more than 1,000 feet into the night.
Inca Treasure Smoothie Pack
This pack of our four most popular superfoods from South America is the perfect combo pack for smoothie lovers.
Pink Himalayan Salt
This salt delivers significant levels of magnesium, zinc and selenium, with trace levels of dozens of other elements.
Pinhole Glasses - Aviator Style
Pinhole glasses are becoming famous for helping people improve their vision without the risks of laser surgery.
Oxy-Rich Facial Serum
O3 Essentials Jojoba Oxy-Rich Facial Serum is cellular nourishment for your skin. Helps smooth fine lines while enhancing tissue elasticity.
Freeze-Dried 100% Blackberry Halves
Our freeze-dried blackberry halves are grown in Serbia under strict organic standards.

Also on NaturalNews:

Health Ranger Videos
Activist music
CounterThink Cartoons
Food documentaries
FREE Special Reports
Podcasts
Colloidal Silver

Advertise with NaturalNews...

Support NaturalNews Sponsors:

Advertise with NaturalNews...

Most Popular Stories

Flu shot kills 19-year-old, but vaccine industry still has total immunity against lawsuits
Here's a nutty fact: Eating more tree nuts lowers the risk of all-cause death by up to 20 percent
Six important facts you're not being told about lost Malaysia Airlines Flight 370
Malaysia Airlines Flight 370 now clearly a government cover-up: All evidence contradicts official story
10 other companies that use the same Subway yoga mat chemical in their buns
BLM fracking racket exposed! Armed siege and cattle theft from Bundy ranch really about fracking leases
High-dose vitamin C injections shown to annihilate cancer
U.S. treating meat with ammonia, bleach and antibiotics to kill the '24-hour sickness'
USDA to allow U.S. to be overrun with contaminated chicken from China
Vaccine fraud exposed: Measles and mumps making a huge comeback because vaccines are designed to fail, say Merck virologists
Battle for humanity nearly lost: global food supply deliberately engineered to end life, not nourish it
Diet soda, aspartame linked to premature deaths in women

25 Amazing Facts About Food

This FREE downloadable report unveils a collection of astonishing and little-known facts about the food we eat very day. Click here to read it now...

 

Resveratrol and its Effects on Human Health and Longevity - Myth or Miracle.

Unlock the secrets of cellular health with the "miracle" nutrient Resveratrol Click here to read it now...

 

Nutrition Can Save America

FREE online report shows how we can save America through a nutrition health care revolution. "Eating healthy is patriotic!" Click here to read it now...

The Healing Power of Sunlight and Vitamin D

In this exclusive interview, Dr. Michael Holick reveals fascinating facts on how vitamin D is created and used in the human body to ward off chronic diseases like cancer, osteoporosis, mental disorders and more. Click here to read it now...

Vaccines: Get the Full Story

The International Medical Council on Vaccination has released, exclusively through NaturalNews.com, a groundbreaking document containing the signatures of physicians, brain surgeons and professors, all of which have signed on to a document stating that vaccines pose a significant risk of harm to the health of children. Click here to read it now...

Health Ranger Storable Organics

GMO-free, chemical-free foods and superfoods for long-term storage and preparedness. See selection at www.StorableOrganics.com



Recommended Resources On:

Natural News trends
Health Ranger news
Natural News GMOs
Mike Adams tracker
Natural News photos
Natural News Global
Natural News in focus
Natural News connect
Natural News shocking stories
Natural News radar
GMOs
Quackwatch
Vaccines
Health freedom
Dr. Paul Offit

This site is part of the Natural News Network © 2014 All Rights Reserved. Privacy | Terms All content posted on this site is commentary or opinion and is protected under Free Speech. Truth Publishing International, LTD. is not responsible for content written by contributing authors. The information on this site is provided for educational and entertainment purposes only. It is not intended as a substitute for professional advice of any kind. Truth Publishing assumes no responsibility for the use or misuse of this material. Your use of this website indicates your agreement to these terms and those published here. All trademarks, registered trademarks and servicemarks mentioned on this site are the property of their respective owners.

eTrust Pro Certified Android app on Google Play

Sign up for the FREE Natural News Email Newsletter

Receive breaking news on GMOs, vaccines, fluoride, radiation protection, natural cures, food safety alerts and interviews with the world's top experts on natural health and more.

Join over 7 million monthly readers of NaturalNews.com, the internet's No. 1 natural health news site. (Source: Alexa.com)

Your email address *

Please enter the code you see above*

No Thanks

Already have it and love it!

Natural News supports and helps fund these organizations:

* Required. Once you click submit, we will send you an email asking you to confirm your free registration. Your privacy is assured and your information is kept confidential. You may unsubscribe at anytime.