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In the exposed children, the average systolic blood pressure was higher than in those who were unexposed (104.0 mm Hg versus 99.4 mm Hg). An increase in diastolic pressure was not statistically significant. Hypertension among children and adolescents is defined based on a range of blood pressures in healthy children, and children above the 95th percentile are considered hypertensive. In the Pediatrics study, nine children exceeded the approximate 95th percentile of 113 mm Hg. Seven of those children had prenatal pesticide exposure.

Prenatal pesticide exposure was also associated with a decreased ability to copy figures presented to the children as part of a standardized Stanford-Binet test. Adjusted regression analysis indicated that the exposed children experienced a developmental delay on this aptitude of four years. The authors noted that the confidence interval, or range of value, for this coefficient was relatively wide but was a statistically significant finding in a study of limited size, suggesting that the effect could be substantial.

In the part of Ecuador in which the children live, malnourishment is frequent. The authors used delayed growth, or stunting, to explore the role of nutrients in the study's results. Stunting is viewed as an indicator of malnutrition and is defined according to a height-for-age scale. Stunting was associated with decreased copying ability in both exposed and non-exposed children. The researchers found that stunting had no clear effect on blood pressure. They therefore concluded that prenatal pesticide exposure may add to the already deleterious effects of malnutrition.

Current pesticide exposure was measured by excretion of pesticide metabolites in urine and was associated with increased reaction time, one of the standardized tests given for neurobehavioral function, indicating that current and prenatal exposures result in different outcomes. Effects caused by exposure in utero may last into childhood.

"These results suggest that more attention should be paid to protecting the developing brain and that we should seriously consider adopting and enforcing a greater margin of safety in protecting both fetuses and children from potential toxic exposures," said Grandjean.