Summary

Original source:
http://www.foxnews.com/story/0,2933,162663,00.html

Details

• Science doesn't yet have an indisputable answer to that question.
• But a report in July's American Journal of Gastroenterology may provide more insight.
• IBS is a functional condition of the intestine.
• While no one fully understands what causes IBS, it is not an anatomic problem.
• According to the American Academy of Gastroenterology, IBS patients have changes in bowel habits, such as constipation or diarrhea.
• They also have abdominal pain along with other symptoms including abdominal bloating and rectal urgency with diarrhea.
• Researchers tested 16 common foods on blood from 132 IBS patients and 43 people without IBS.
• IBS patients had higher levels of an antibody called IgG4 in response to five foods, compared with those without IBS.
• Those five foods were wheat, beef, lamb, pork, and soybeans.
• IgG is the major antibody in the body; another antibody called IgE is normally present in only trace amounts, but it is responsible for the symptoms of allergy.
• They included Sameer Zar, MRCP, of St. Georges Hospital Medical School in London.
• Between one-fifth and two-thirds of IBS patients attribute their symptoms to food hypersensitivity.
• By comparison, only about 5 percent of the general population claims food hypersensitivity.
• Zar's study included 52 people with diarrhea-prominent IBS, 32 with constipation-prominent IBS, and 24 with alternating IBS.
• Those with diarrhea-prominent IBS had markedly higher levels of the antibody IgG4 for wheat, beef, pork, and soybean.
• Skin prick tests were done on a smaller group of participants -- 56 with IBS and five without IBS.
• A skin prick test places a small amount of substance that triggers an allergic reaction into the skin.
• The skin test results didn't sync up with results from the blood antibody tests, write the researchers.
• Read WebMD's "Newly Diagnosed with Irritable Bowel Syndrome?

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