Summary

Original source:
http://www.sciencedaily.com/releases/2004/12/041220023731.htm

Details

• For the first time scientists have demonstrated a model that may explain how alcohol stimulates tumor growth. says alcohol fuels the production of a growth factor that stimulates blood vessel development in tumors, and that chronic ethanol increased tumor size and levels of the angiogenic factor and levels of the angiogenic factor and vascular endothelial growth factor (VEGF) in an experimental model.
• For almost a hundred years mounting epidemiological evidence has linked alcohol use to an increased risk of cancers of the stomach, esophagus, liver, breast, and colon.
• Researchers have never developed an adequate model to explain how ethanol or a metabolite of ethanol may cause cancer.
• Hypotheses abound, and include such diverse theories as acetaldehyde carcinogenicity, dietary imbalances, and impaired nutrient metabolism and detoxification due to alcohol consumption, activation of precancerous enzymes, and suppression of the immune system.
• Recent data in a cellular model has demonstrated that ethanol increases cellular production of VEGF, an important signaling protein in blood vessel growth, particularly in tumors.
• M.D. from the University of Mississippi Medical Center and colleagues further investigated the possible mechanism between ethanol-induced blood vessel growth and VEGF using a chick embryo model.
• The investigators exposed chick embryos inoculated with fibrosarcoma cells to saline or physiologically relevant levels of ethanol for nine days.
• The investigators found that compared to the saline control group, the embryos exposed to ethanol experienced increases in tumor size, tumor blood vessel density, cancer cell infiltration of blood vessels, and VEGF levels.
• The authors say their findings "support the hypothesis that the induction of angiogenesis and VEGF expression by ethanol represent an important mechanism of cancer progression associated with alcoholic beverage consumption."

Related Articles

Popular Topics: Alcohol, Ethanol, Cancer, Diabetes, Breast cancer, Prostate cancer, Heart disease, Depression, High cholesterol, Osteoporosis, Vaccines, Autism, ADHD, Infertility, Weight loss, Cancer, Alzheimer's, Trans fats, Acrylamides, Fluoride, Mercury	Take Action: Support NaturalNews.com Email this article to a friend Share this article on: NewsVine | digg | del.icio.us Permalink to this article: http://www.NaturalNews.com/003318_alcohol_ethanol_cancer.html Reprinting this article: Non-commercial use OK, cite NaturalNews.com with clickable link. <a href = "http://www.NaturalNews.com/003318_alcohol_ethanol_cancer.html">Research shows how alcohol is linked to cancer</a>
Receive our Natural Health Newsletter for FREE Subscribe now (it's free!) to win. We randomly choose a subscriber each month to send $100 in eco-home products or a RealGoods.com gift certificate (our choice). Plus, you'll receive FREE news, articles and action alerts from NaturalNews.com editors and join over 800,000 monthly readers who report extraordinary health improvements after becoming a subscriber! Receive breaking news alerts on natural health solutions, renewable energy, the environment, global warming and more. Receive a free instant download of our $29 Secret Sources guide that reveals top sources for little-known health and diet solutions.	Your Email Address: Free Subscription Code: Enter the numbers you see: 100% free of charge. Unsubscribe anytime. Absolutely no spam. We respect your email privacy.
Recommended Special Report: Seven Words that can Change the World by Joseph R. Simonetta Read this special report now... "Seven Words That Can Change the World reveals the astonishing, simple truths that have the power to forever transform our world for the better while freeing our minds from the enslavement of limiting beliefs. This is not a text for the simple-minded; it is a guiding philosophy for the mindful, intelligent few who are wise enough to seek out -- and recognize -- the higher simplicities of truly purposeful living." - Mike Adams, the Health Ranger, editor of NaturalNews.com	More on NaturalNews.com: • Streaming Health Ranger Videos • CounterThink Cartoons • FREE Special Reports • Podcasts